Professor Emily Banks, 45 and Up Scientific Director, Sax Institute, gave an update on the 45 and Up Study at our 2012 Annual Collaborators' Meeting. This meeting is an annual event that offers our research partners, supporters and other interested parties the opportunity to receive a comprehensive update on the Study’s progress and updates on research projects that are using the Study resource. The meeting is also an opportunity for researchers, health decision makers and evaluators to engage and discuss the potential for maximising the Study’s value. For more information, visit www.saxinstitute.org.au

1. The 45 and Up Study Update
Professor Emily Banks
In partnership with

2. Today
• Brief background
• Study progress
• Highlights
• Priorities

3. The 45 and Up Study
• The largest long term study of ageing in Australia
• A collaborative resource available for use by
researchers and policy makers
• Core funding from major partner Cancer Council NSW
and partners the National Heart Foundation of Australia
(NSW Division); beyondblue: the national depression
initiative; NSW Health; Ageing, Disability and
Home Care, Department of Human Services, NSW; Red
Cross Blood Service and UnitingCare Ageing

4. Recruitment
• 267,153 men and women
aged 45 years and over
recruited from 2006 to 2008
• Over 1 in 10 people in this
age group
• Sampled through Medicare
Australia
• Baseline questionnaire and
consent for long term
follow-up

5. 0y 5y 10y
recruitment follow-up follow-up
ROUTINE DATA
OTHER DATA LINKAGE
resurvey of selected individuals
NESTED STUDIES

6. Data
• Moving to use of the SURE facility
• Full cohort included in the Master Linkage Key for the CHeReL
• Linked PBS and MBS data on the cohort available:
use through SURE
• More detailed survey data received from 60,000 participants:
available following exclusive use period
• Follow up questionnaire

7. Data linkage
• CHeReL data from 267,153 matched participants,
mid 2000-mid 2011:
– 1,290,692 hospitalisations
– 347,799 emergency department presentations
– 11,028 deaths
– 28,955 cancer registrations
• National Death Index data – available soon through AIHW

8. Research overview
• 126 project applications
– 114 projects approved to use the data
– 74 active, 13 completed
• 447 researchers
– 41 institutions
– 61 early career researchers

9. 14000 60
cumulative peer-reviewed publications
12000 cumulative project funding ($, '000s)
50
10000
40
8000
30
6000
20
4000
2000 10
0 0
2007 2008 2009 2010 2011 2012
Year

10. Highlights since last meeting
• grant success, especially health services research
• publications in leading international journals
– sitting time and mortality
– prospective study of pertussis
– body mass index and hospitalisation
– smoking and social interaction
• media
• methodological work

11. Sitting time and mortality

13. Major initiatives
• cancer
• CVD
• diabetes
• mental health
• healthy ageing
• social inequalities
• health services: primary care, acute care, medicines, prevention
• Aboriginal health

14. Priorities
• Follow-up survey
• 41,000 sent out

15. Priorities
• Continuing follow-up
• Transition to SURE
• Streamlining data provision
• Increase profile
• Cohort retention and tracking
• Biobank

16. Masterclass
• 3.30 to 4.30 pm this afternoon
• Applying for grants using the 45 and Up Study
• Optional

17. Thank you ...
In partnership with