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Biotechnology engineering
1. Engineering: a key knowledge for boosting the
competitiveness of biotechnology-based companies:
2. PRODINTEC – Introduction
Date created:
October 2004. Formed as a private non-profit. Board
composed of private companies in Asturias, University
and Government of the Principality of Asturias.
Location:
Science and Technology Park of Gijón (Asturias)
Delegation in Madrid:
Science and Technology Park of Madrid, PC 28760
Madrid
Tarjet
Enhancing competitiveness of enterprises through the application of technological advances both
their products and their manufacturing
processes and management.
5. Innovation
Fuente: The Global Competitiveness Report 2011–2012
http://www3.weforum.org/docs/WEF_GCR_Report_2011-12.pdf
39º worldwide position
36º in Europe
6. What is the reason?
Who would go?
What steps do I follow?
How I can have functional prototype
pre-series or commercial?
How I can industrialize my idea?
7. • Improving the quality of life of individuals and society
Why innovate in Biotechnology?
Technologies, techniques, tools, equipment, devices, medical and surgical
procedures, information systems, health programs, organization forms for
the prevention, diagnosis, treatment and rehabilitation.
DEMAND AS
SOCIETY
THE ECONOMY AS
REQUIRED
TECHNOLOGY
ALLOWS
HEALTH
8. • From the research to the market
- Companie
- Research group
- Spin Off
- Hospital
- Tech Based
companies
Estrategic
Definition
Producto
definition
Conceptual
Design
Concept
generation
Detailed
design
Specification,
assembly
drawings,
prototypes
Product
Engeneering
Technical
Solution and
Manufacturing
drawings
Production
Manufacturing
Process definition
Merchandising
CD DD PE P MED
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Return
Licensee
Law firm
1. Detect potentially interested
2. Contact potential applicants
3. Negotiations and drafting
transfer agreement
Return
+
+
+
M
a
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k
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t
VIABILITY,
INTELECTUAL
PROPERTY RIGHTS
Value chain
9. • Provide technical support from invention / patent to the market.
• Provide technological muscle for design and manufacturing process to
provide "value" to the contact process, selection and negotiation with a
licensee end.
- "Convince" the licensee of the technical end.
- Checking the operating principle and development prototypes to
assist in this process.
• Cover the gap between the licensee and technical office, production and
commercialization.
- Provide tools that facilitate the industrialization and placing on the
market
Objetives
10. IVD:
Kits and diagnostic devices, sensors, microfluidics, etc..
Detection and measurement of biochemical and biological parameters, identification of toxic
substances, drugs, etc..
Biomedical engineering:
Surgical tools, implants, custom designs, accessories, new features, etc..
Food Biotechnology:
Systems for use in situ detection of contaminants or pollutants detection of biological agents.
Biosensors / Equipment / Instruments:
Prototypes (first series, enclosures, laboratory equipment, cells, interfaces, developing
analytical instrumentation, robotics).
Security and Defence:
Devices for the detection of biochemical weapons,
explosives, and drugs, etc..
Biocatalysis/ Bioreactors
Scale-up, Industrialization, bioreactors design
and manufacturing, etc.
Applications
14. Biomedical Models
Generation 3D Modeling
and CAD
Patient/Model
Choice of technology and
manufacturing
Rapid production of 3D models at low cost. Time
reduction interventions, better communication and
decision making, precise adjustment of implant training.
Applications
15. Tools, Implants, orthopedic, …
Generation 3D Modeling
and CAD
Need, implementation,
//Know how/Idea
Choice of technology and
manufacturing
16. Medical Devices, PoC, Biosensors, …
Mechanical design and
generation of CAD
Protocolo
Electrical and electronic
design of the device,
reading system, control,
+
Choice of technology and
manufacturing
Test Product
17. Equipment, Instruments, Machinery…
Mechanical design and
simulation
Need / New functionality /
Machinery ad hoc
Electrical and electronic
design of the device,
reading system, control,
...
+
Choice of technology and
manufacturing
Test Product
3D modeling and design
of components
+
19. Case Studies
Design and manufacture of a diagnostic device and electrochemical detection.
Objective: miniaturization, microfluidics [capillary electrophoresis chips], portable,
communication USD / Bluetooth.
20. Case Studies
Instrumentatión Rakes
Instrumentation rakes or combs.
- Pressure and temperature
probes
- To manufacture complex parts
- Withstands high temperatures
Manufacture:
- SLS part made by Inconel
- Polished finish
- Manufactured in one piece
21. EOSINT M-270 EOS FORMIGA P-100
Machine Fabrication of direct metal laser sintering:
Able to work with steels, stainless steels, cobalt chrome, brass,
titanium, etc.. Layered fabrication technology that can produce
finished parts from 3D CAD and metal powders. Typical
applications: complex geometric parts, tools, molds with
conformal channels, custom inserts, prosthetic devices, etc..
Manufacturing Machine direct laser sintering of plastics:
Able to work with plastics, nylons, etc.. Layered fabrication
technology that can produce finished parts from 3D CAD and
polymeric materials. Typical applications: complex geometric parts,
machinery parts and small series without making molds, etc..
EOS P-395
Equipment
EOSINT M-280
Aplications
22. OBJECT CONNEX 500EDEN 330 multijet
Rapid Prototyping:
Prototyping PolyJet technology by injection consisting of
photoresists and later cured by ultraviolet light. Direct
connection to CAD and engineering software reverse
PRODINTEC
Rapid Prototyping:
Prototyping PolyJet technology by injection consisting of
photoresists (possibility of use of 2 different polymer resins
simultaneously) and later cured by ultraviolet light. Direct
connection to CAD and engineering software reverse
PRODINTEC
Equipment
Aplications
Industries
Materials
Case Studies
23. ZCORP Z510MCP 4/04
Vacuum Casting:
Making pre-series in plastic and metal from a physical part.
Rapid prototyping, prototyping based on material by dust
and its suburbs by colored liquid. Infiltration finish with
cyanoacrylate (getting very hard piece) or epoxy resin (flexible
piece collection).
Equipment
Aplications
Industries
Case Studies
24. KERN Evo
Wittmann-Battenfeld
Microsystem50
Microinjection machine,
that allows the injection of
plastic parts, metal and ceramic
micro geometries, handling,
quality control and automatic
blister packaging clean room.
Micromilling machining by chip
removal in high speed, to obtain
absolute accuracies in the vicinity of
one micron. Applications in the field
of micro and nanotechnologies
Equipment
MicromillingMicroinjection
Deckel Maho
Milling
fully equipped robotic cell for automated
manufacturing via the machining of large
parts (measuring up to several metres), with
accuracies of tenths of a millimetre and in
materials such as resin, wood, expanded
polystyrene, etc.
We also have a high-speed 5-axis milling
machine that allows us to produce very high
precision parts with complex geometries in
any material
25. MecathronicsCemLab
Electromagnetic Compatibility Laboratory: Performing
compatibility tests or external devices developed at the Center
for CE marking
Mechatronics: Design and development of electronic circuits.
Instrumentation, control and measurement. Process
automation.
PCB prototyping equipment.
Equipment
26. In short…
1.- Full development of device from companies know how to prototype or
functional first series.
2.- Manufacturing direct piece further tools and functionalities in teams.
3.- Design and manufacture of machinery and devices for analysis, sensors and
biosensors for diagnosis.
4.- Design and manufacture of interfaces, cells supports analysis kits ...
5.- Manufacture of medical model to patient.
6.- Design and manufacture of devices for detection and sampling.
7.- Unlocking the design constraints of traditional manufacturing processes.
8.- Access to new market niches.
9.- Reduce costs in small series.
10.- "Mass customization", batch unit, as ...
EXAMPLES OF APPLICATION
medical implants, orthopedic products, support structures, surgical tools,
diagnostic devices, interfaces, flow cells, envelopes, microarrays ....
27. EKA
International Projets
ESTIIC RFID4SME
NANO4M www.nano4m.eu/
INTERREG
Frame Program
FP6: Syntex www.syntex.or.at/
FP7: Light-Rolls (coordinador)
www.light-rolls.eu/
FP7: NANOfutures (CSA)
FP7: CIS3D (NMP)
Technology Platforms
Rapid Manufacturing European
Plaftorm
Prodintec manager is a board
member
European Technology Platform
Manufuture
Platform manufacturing
technologies. In his likeness created
the regional platform PRODINTEC
Manufacturias
MINAM +NANOfutures
Micro and nanofabrication
platforms
Prodintec Manager is a board
member
Prodintec also a member of: Iberian Red RICAI Center for
Innovation, Red PYMERA, Europe InterCluster, HISPAROB Spanish
Technology Platform on Robotics and Technical IDESA Consortia
International Presence
29. Centro tecnológico para el diseño y la producción industrial
PRODINTEC
EDIFICIO CENTROS TECNOLÓGICOS
PARQUE CIENTÍFICO Y TECNOLÓGICO
33203 GIJÓN. ASTURIAS
T +34 984 390 060
F +34 984 390 061
www.prodintec.com
DELEGACION EN MADRID
T +31 667 728 947
www.prodintec.com
