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Empowering Personalized Cancer Treatment 
October 2014
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 2 
Forward-Looking Statement 
This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services or Gentris, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks related to integration of the acquisitions of Gentris and BioServe and the realization of the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company's Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended June 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 3 
Focused On Personalizing Cancer Diagnosis and Treatment 
Globally Through Genomics 
 Develop & Commercialize Unique Targeted Panels For The 
Comprehensive Assessment of Cancer 
 Develop Compelling Collaborations With Leading Institutions To Support 
Genomic Test Adoption, Validation & Health Economics 
 Establish Sales, Marketing & Commercial Infrastructure In US & India 
 Serve Both the Clinical and Biopharma Communities Leveraging A 
Standardized Global Infrastructure 
 Selectively Acquire Companies & Capabilities That Further Our Mission of 
Impacting The Personalization of Cancer Diagnosis & Management
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 4 
Molecular Diagnostics are Changing our Understanding of Cancer While Providing New Tools to Diagnose & Treat Patients 
Our unique focus & approach supports the entire cancer care continuum 
Personalize therapeutic plan and treatment options 
DIAGNOSIS 
PROGNOSIS 
THERANOSIS 
Assist in patient outcome and disease management 
What drug(s) to give, how much, and when? 
What are my survival prospects? 
Do I have cancer and what type? 
Use genomics to provide an accurate and definitive typing of the cancer 
Proprietary Products Focused Oncology Lab Comprehensive Report 
Integrated Molecular Diagnostic Testing Brings Benefits 
Across the Entire Oncology Ecosystem
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 5 
CGI’s Mission is to Personalize and Improve the Success Rate in Cancer Treatment 
Integrating & Delivering Genomic Information About a Patient’s Cancer 
Can Improve Care & Reduce Cost 
Phenotypic & Physical Examination 
Morphologic & Pathological Analysis 
Large & Multiple Specimens Required 
Significant Delays to Treatment 
Traditional Approach 
Biomarkers and Companion Diagnostics 
Genomic Analysis & Proprietary Algorithms 
Reduced Size and Number of Specimens 
Improved Diagnoses & Treatment Plans 
Our Approach: Personalized Medicine 
Target For Tomorrow 
25% 
Situation Today 
Source: Clinical Trends in Molecular Medicine, Vol. 7, Issue 5 
100% 
Success Rate 
Target Success Rate
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 6 
The Acquisitions of BioServe India and Gentris Corporation Provide Significant Market Upside & Improve CGI’s Competitive Position 
•Growth potential in integrating our oncology- focused testing capabilities with Gentris’ high-value contracts. 
•Expansion of Gentris’ capabilities and portfolio to include oncology-focused pharmacogenomics services. 
•24,000 sq. foot lab space (CLIA/CAP/GLP) with NGS, genotyping, and gene expression test capabilities. 
Gentris Corporation 
[Closed 7/16/14] 
•Access to high-growth Indian diagnostics market – projected to grow at 15-20% per annum for the next decade. 
•Accelerates next-generation sequencing development and validation of targeted hot spot oncology panels. 
•Cost-effective expansion of genomic analysis & informatics capabilities with state of-the-art 14,000 sq. foot lab. 
BioServe India 
[Closed 8/18/14]
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 7 
Our Expansion is Crucial for our Global Positioning as an Industry Leader in Genomics Testing and Services 
Clinical Services and R&D 
82 Employees as of July 1st 
CGI is positioned as leader in oncology-focused genomics and is enabled to deliver 
complete solutions to the clinical and research communities. 
Clinical & Research Services 
Addition of 33 employees 
Pharmacogenomics Services 
Addition of 41 employees
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 8 
Unique, Scalable and Multifaceted Business Model With A Focus On Providing A Complete Solution 
Suite of Products and Services Provides Multiple Growth Drivers and Value to Multiple Parties: Clinical Community, Biopharma & Medtech 
CLINICAL SERVICES 
Differentiated and complete disease-focused solutions 
Superior turnaround times 
World-class expertise in genomics and cytogenetics 
Serving community hospitals and labs through unique Expand Dx™ program 
BIOPHARMA PARTNERSHIPS 
Biomarker and companion diagnostic development 
World-class genomics and bioinformatics 
Drug-specific and cancer-specific assays 
Comprehensive focus in hematologic & urogenital cancers 
PROPRIETARY PRODUCTS 
Proprietary molecular diagnostics & FISH probes 
Clinically validated 
IP-protected 
Sold globally 
Probe manufacturing leverages low-cost, high scale facility in India
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 9 
Our Target Markets in Oncology Testing Comprise Over 615,000 New Lives Annually in the U.S. 
Ability to Impact Over 615,000 New Lives Annually in the U.S. 
Source: American Cancer Society 
156,420 
2014 Estimated New Cases 
(U.S.) 
Death Rate 35% 
Hematological: 
Lymphoma, Leukemia, M. Myeloma 
371,610 2014 Estimated New Cases (U.S.) 
Death Rate 16% 
Urogenital: 
Kidney, Bladder & Prostate 
86,970 
2014 Estimated New Cases 
(U.S.) 
Death Rate 31% 
Gynecological: 
Cervical, Endometrial & Ovarian 
6 Products Launched in Target Segments Over $6Bn in Annual U.S. Spend on Lab Testing In These Categories
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 10 
6 Proprietary Diagnostic Products Commercially Launched & In Market 
Incidence 
Indication 
Hematologic Cancers 
106,770 
(Annual New Cases, Global) 
Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma 
142,360 
(Annual New Cases, Global) 
Diffuse Large B-Cell Lymphoma 
62,300 
(Annual New Cases, Global) 
Follicular Lymphoma 
17,795 
(Annual New Cases, Global) 
Mantle Cell Lymphoma 
Urogenital Cancers 
274,000 
(Annual New Cases, Global) 
Kidney Cancer 
HPV-Associated Cancers 
(FHACT®) 
1,750,000 
(Annual New Cases, US) 
HPV+ Low Grade Cervical Lesions 
Over 2.3 Mn Combined Annual New Cases Globally
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 11 
Product Pipeline 
Research & 
Discovery 
Clinical 
Development 
Commercial Development 
Launch & 
Market Entry 
Indication 
Development Stage 
Hematologic Cancers 
Multiple Myeloma 
Comprehensive Myeloid Panel 
[NGS-based] 
Comprehensive CLL Panel 
[NGS-based] 
UroGenital Cancers 
Bladder Cancer 
Comprehensive Renal Panel 
[NGS-based] 
Cervical Cancer 
HPV-Associated Cancers 
(FHACT®) 
Head & Neck Cancer
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 12 
Despite Improved Cancer Care, Case Numbers for Hematologic Cancers are Still Rising 
Genomics-Based Tests like MatBA® are Critical and Improve the Management and Cost of Hematologic Cancers 
Source: Genzyme & Nature 
Source: National Cancer Institute, National Center for Health Statistics, SEER Dataset of Incidence & Mortality, FDA 
1 
2 
5 
12 
89 
100 
80 
60 
30 
2 
Number of Years Ago 
11.1 
12.6 
15.5 
18.5 
20.0 
19.7 
20.5 
21.2 
5.6 
6.2 
7.1 
7.9 
8.7 
8.2 
6.9 
7.3 
1975 
1980 
1985 
1990 
1995 
2000 
2005 
2010 
Incidence Rate 
Survival Rate 
Identified Leukemia & Lymphoma Subtypes 
Incidence & Survival Rates for NHLs 
(US Only, per 100,000)
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 13 
MatBA®-CLL/SLL Improves Risk Stratification & Outcome Prediction 
Validated in Collaboration w/ Dr. Kanti Rai & Dr. Nicholas Chiorazzi (NSLIJ); 2 Datasets, 322 specimens 
Additional Validations being conducted w/ HUMC & Dana Farber; 2 Cohorts, 350+ specimens 
█ Favorable 
█ Intermediate 
█ Unfavorable 
█ Favorable/ 
Intermediate 
(no distinction) 
38% of cases in our study have a favorable prognosis falling under "watch & wait" approach. 
8% of cases with unfavorable prognosis missed by FISH and caught using MatBA®-CLL/SLL. 
Impact on therapy selection & clinical management of CLL patients. 
Genomic Aberrations Reported 
by FISH: 
4 
Genomic Aberrations Reported 
by MatBA®-CLL/SLL: 
20 
85% 
15% 
FISH 
23% 
39% 
38% 
(Current Method) 
(CGI Method)
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 14 
MatBA® can Group Patients into Risk Groups & Prognostication Classes 
MatBA®- CLL / SLL is a diagnostic tool and prognostic indicator for patient stratification and improved patient management 
Being actively used in clinical care, in clinical trials and in validation programs with Dana Farber, MSKCC and HUMC 
20 key genetic events/sites classify CLL patients as having the potential for Poor outcome = High risk Intermediate outcome = Intermediate risk Good outcome = Low risk Detection of specific genomic imbalance in CLL/SLL by MatBA®-CLL/SLL correlates patient risk with time to first treatment (TTFT) and shorter overall survival (OS) 
Patients classified as high risk showed a shorter TTFT compared to those classified as low or intermediate risk 
Patients classified as high risk had significantly shorter OS times than those classified as low or intermediate risk 
Provides additional risk stratification between low and intermediate risk patients, not currently available in other tests 
Time to First Treatment (TTFT) 
Time (months) 
Time (months) 
Proportion Surviving 
Proportion Treatment- Free 
– GOOD (n=74) 
– INTERMED (n=107) 
– POOR (n=47) 
– GOOD (n=74) 
– INTERMED (n=107) 
– POOR (n=47) 
P = 0.090 
P = 0.001 
P < 0.001 
P = 0.010 
Overall Survival (OS) 
Leukemia & Lymphoma – Houldsworth, et. al Sept. 18, 2013
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 15 
UroGenRA®-Kidney Can Guide Management of Patients with Renal Masses and Appropriate Treatment Selection 
Clinical Benefits Include Reduction in Number of Highly Invasive Procedures and Time to Treatment Initiation, and Better Informed Treatment Selection 
Development of diagnostic algorithm 
>600 RCC malignant subtypes (in-silico: SNP) 
>100 malignant and benign renal neoplasms (in-house: aCGH & FISH) Retrospective in-house FFPE validation (n>190) CCF 
100% diagnostic yield 
97% diagnostic sensitivity to distinguish benign from malignant renal neoplasms 
93% sensitivity to distinguish malignant RCC subtypes 
C. Magi-Galluzzi and E. Klein (Cleveland Clinic) Prospective ongoing percutaneous core needle biopsy (n>50) MSKCC 
Demonstrated ability to diagnose pathologically “unclassifiable” biopsies prior to surgical intervention 
J. Coleman and J. Durack (MSKCC) 
PROBLEM 
Men and women with renal masses often undergo unnecessary nephrectomy for accurate diagnosis and experience delay in treatment 
SOLUTION 
UroGenRA® will detect genomic aberrations in a single assay permitting accurate diagnosis (benign vs malignant, and malignant subtype) guiding appropriate management and treatment strategies
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 16 
FHACT® - A New Genomic Aid In The Screening & Management Of Cervical Cancer 
FHACT® Provides Critical Information Which Reduces 
Unnecessary and Costly Colposcopies 
Cervical cancer effects nearly 500,000 women globally each year with nearly 80% in developing countries. 
Today, all these women are referred for colposcopy. 
Women with abnormal or unclear Pap smears 
55 Million 
Pap smears per year 
3.5 Million 
Pap smears come back as unclear/abnormal 
2 Million 
biopsies performed 
12,000 
cases of cervical cancer
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 17 
FHACT® Provides Information for Developing Treatment Plans Potentially Reducing Healthcare Costs & Procedures 
FHACT® is the Only 4 Color FISH Probe that can be Used for Cervical Cancer Screening 
as Additional Testing Before Referral for Colposcopy 
Global Validation Partners 
Genomic Amplification by Disease Category 
Source: P. Luhn, J. Houldsworth, et al., Gynecologic Oncology (2013) 
5 
10 
19 
20 
0 
20 
40 
60 
80 
ptrend = 0.01 
6 
9 
9 
20 
0 
20 
40 
60 
80 
ptrend = 0.02 
6 
9 
7 
12 
0 
20 
40 
60 
80 
ptrend = 0.03 
3 
8 
12 
12 
0 
20 
40 
60 
ptrend = 0.001 
<CIN2 
& NLIM 
(n=11) 
<CIN2 & LSIL (n=20) 
CIN2 
&/or HSIL 
(n=10) 
CIN3+ 
(n=7) 
<CIN2 
& NLIM 
(n=11) 
<CIN2 
& LSIL 
(n=20) 
CIN2 
&/or HSIL 
(n=10) 
CIN3+ 
(n=7) 
FHACT® detects irreversible changes in cervical cells caused by HPV.
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 18 
IP Position and Detailed Global Strategy 
Strong and growing portfolio in molecular-focused patents for disease identification and stratification 
IP-based on unique algorithms across a broad group of chromosomal regions 
Validation of specific clinical endpoints that are associated with particular disease outcomes or decisions 
Filing and maintenance of trademark portfolio 
Tool for Diagnosis and Prognosis of Mature B-Cell Neoplasms 
US Issued Patent 8,580,713 
US Issued Patent 8,557,747 
Europe 10803548.6 
India 6657/DELNP/2012 
Canada 2,785,656 
Methods of Analyzing Chromosomal Translocations Using Fluorescence In Situ Hybridization (FISH) 
US Issued Patent 7,585,964 
US Issued Patent 7,964,345 
Canada 2,447,320 
Panel for the Detection and Differentiation of Renal Cortical Neoplasms 
US Issued Patent 8,603,948 
US 14/078,726 
Europe 08844570.5 
Methods for Detecting Human Papilloma Virus-Associated Cancers 
US 13/227,027 
US 13/474,111 
PCT/US2011/050681 
Methods and Tools for the Diagnosis of Female Gynecological Cancers and Precancers 
US 61/581,350
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 19 
Large, Targeted Market Opportunities 
Target Markets 
Commercialization Strategy 
Community Hospitals 
Regional Cancer Centers 
Oncologists and Pathologists 
Continue to growing sales force that calls on hospitals and regional laboratories 
Plan development of national footprint through Expand Dx™ 
Biotechnology Companies 
Pharmaceutical Companies 
Leverage clinical infrastructure and proprietary product portfolio for testing services that support clinical trials 
Expand sales emphasis of Select One® 
Emerging Markets 
Enhance distributor base in select emerging economies 
Partner with leading local cancer care providers and hospitals to provide probes, arrays and clinical services 
Collaborate to create and validate microarrays and other proprietary products 
Accelerate launch of large scale studies 
Universities and Research Centers
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 20 
Unique Service Offering Developed to Enable Community Hospitals to Improve Cancer Outcomes & Treat Patients Locally 
Delivers better outcomes to community hospitals and laboratories 
Enables community hospitals to bring “state-of-the-art” genomic testing to patients 
Brings personalized medicine to the community hospital vs. just at academic and teaching hospitals 
Allows community hospitals to keep patients and treat them locally 
Improving care and quality is critical to maintaining reimbursement for community hospitals 
$600,000 - $800,000 USD in Testing Opportunity on Average per Hospital 
Expanding & Developing Cancer Care is a Top Priority for Hospital CEOs & CFOs 
4,000 to 5,000 Community Hospitals & Laboratories in the U.S. 
85% Of All U.S. Cancer Patients are Initially Diagnosed in Community Hospitals & Laboratories
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 21 
Through Acquisition, Clinical Trial Services Show Strong Growth and Robust Pipeline 
Gentris Provides Pharmacogenomic Clinical Trial Services to Several Large Pharma Companies Including Merck, Novartis, Otsuka, Eisai and Bristol-Myers Squibb 
GROWTH IN CGI’s SELECT ONE® CONTRACTS ($000) 
21% 
55% 
ONCOLOGY DRUGS ASSOCIATED WITH BIOMARKER(S) 
$300 
$2,700 
$8,500 
$18,000 
2011 
2012 
2013 
2014 
Approximate value of contracts with biotech and pharma clients 
2011 
2016 
Source: Company Analysis and Management Estimates
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 22 
Over 6,800 Oncology Trials in the US Aligned with our Core Markets 
Number of Open Clinical Trials (U.S.) 
1,439 
1,453 
2,178 
1,765 
Lymphoma 
Leukemia 
Urogenital 
HPV-Associated 
Source: www.clinicaltrials.gov
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 23 
Gilead is Currently Using a Comprehensive Panel of CGI Services & Proprietary Products in National & International Trials for Hematologic Cancers 
The Gilead Relationship Exemplifies the Significant Upside Potential of 
CGI’s Select One® Offering 
Highlights 
Comprehensive, biomarker-based patient profiling will help risk stratification and response monitoring 
Improved patient profiling will result in improved trial efficacy for Gilead 
Testing will occur across several methodologies, including flow cytometry, FISH, sequencing and mutation assays, and MatBA® microarrays 
CGI provides biomarker driven insight regarding patient targeting and potential outcomes 
Trials cover both national and international locations with all patient specimens being processed in Rutherford, New Jersey 
CGIX Press Release: Cancer Genetics, Inc. Selected By Gilead Sciences, Inc. to Provide Clinical Trial Services for International Trials in Chronic Lymphocytic Leukemia
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 24 
Roche Partnership Expanding Market Presence Internationally 
“By expanding our relationship, we are strengthening our ability to provide patients the best service possible.” Alvaro Soto, Roche Servicios, Central America & Caribbean General Manager 
Highlights 
CGI provides genomic and biomarker testing services to 14 countries in Central America and the Caribbean. 
CGI won a global RFP to help a strategic personalized medicine initiative for Roche Servicios (Latin America) 
Roche sends all patient samples to the Rutherford facility where they are catalogued and processed 
CGI interacts with both Roche and the hospital staff (pathologists, oncologists and nurses) and supports delivery of reports through an online HIPAA compliant portal 
CGI and Roche expanded this relationship in 2013 and will begin developing workshops and training programs to drive adoption of biomarker-based cancer diagnostics throughout Central America and the Caribbean 
CGI and Roche recently further expanded this relationship with an exclusive multi-year deal in which CGI will develop a center of excellence for lung cancer testing utilizing Roche’s FDA-Approved cobas® platform 
CGIX Press Release: Cancer Genetics, Inc. selected by Roche Servicios S.A. to provide services for the diagnosis and personalization of oncology treatment CGIX Press Release: Cancer Genetics, Inc. expands relationship with Roche Servicios S.A.
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 25 
AstraZeneca Partnership A Testament to the Growing Global Awareness of the Value of the CGI Brand 
“We chose to partner with Cancer Genetics in this endeavor because of their experience in biomarker-based diagnostic testing and their commitment to delivering timely and accurate results to healthcare professionals and patients.” Rodrigo Fernandez, Country President of AstraZeneca CAMCAR, S.A. 
Highlights 
CGI will provide biomarker and molecular based testing services focused on select oncology categories and trials 
Services include complex testing for diagnosis and prognosis of cancer patients in Central America and the Caribbean 
CGI will work in close conjunction with AstraZeneca on exploring expansion opportunities into additional geographic territories, further oncology categories, and into select oncology trials 
The partnership will concentrate on multiple cancer categories, with lung cancer being an initial area of focus 
CGIX Press Release: Cancer Genetics, Inc. Announces Partnership with AstraZeneca to Provide Biomarker & Molecular Based Testing
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 26 
Collaborations with Premier Cancer Research Institutions Leading Differentiated Research & Driving Product Adoption 
Research Collaboration/ Licensing 
Clinical 
Services 
Partnership 
Highlights 
 
 
Kidney Cancer, DLBCL, MCL & FL 
 
Joint Venture Focused on Oncology & Next Generation Sequencing 
 
Cervical Cancer 
 
DLBCL 
 
 
CLL 
 
 
Cervical Cancer & DLBCL 
 
Cervical Cancer 
 
Kidney Cancer 
 
 
DLBCL, Head & Neck Cancers 
 
 
CLL
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 27 
Mayo Clinic Joint Venture Investing in the Future – OncoSpire Genomics 
The Value and Focus of Next Generation Sequencing is Moving from Platforms to Clinically Relevant, Disease-Specific Applications 
Highlights 
JV, based in Rochester, MN, will develop clinical diagnostic products and services on NGS platform(s) in areas of high clinical need 
Three initial projects in key oncology categories selected by the SRC (Scientific Review Committee): Lung Cancer, Multiple Myeloma, Follicular Lymphoma 
CGI commits up to $6 M over initial three year period (2013 to 2015-16 expected) 
Mayo commits to “in-kind” services and support, use of facilities, NGS capabilities and access to biorepository 
Joint Venture is exclusive in the project areas selected by CGI & Mayo 
Important company update and analyst day held November 22, 2013 
Next Generation Sequencing in Oncology
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 28 
OncoSpire Genomics Projects are Unique and Have High Value 
1.6 million 
new cases 
200,000 
new cases 
20,920 
new cases 
Informed 
Discovery 
Clinical Development 
Commercial Development 
Market Entry 
(with partners) 
Lung Cancer 
Multiple Myeloma 
Follicular Lymphoma 
Selected Projects Have Significant Clinical Value & May Yield Multiple Focused Panels to Become the Standard of Care in NGS-Based Oncology Management
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 29 
Strong History of Growth CGI Revenue & Clinical Volume Trends (2009 – 2013) 
54% Full Year 2013 Revenue Growth 
$1.67 
$2.52 
$3.02 
$4.30 
$6.61 
2009 
2010 
2011 
2012 
2013 
2,321 
3,146 
3,622 
6,610 
10,771 
2009 
2010 
2011 
2012 
2013 
Total Revenue ($Mn) 
Clinical Volume (Tests Processed)
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 30 
Strong History of Growth - Revenue & Clinical Volume Trends (Q2 Comparison 2012-2014) 
$1,148 
$1,832 
$3,231 
Q2, 2012 
Q2, 2013 
Q2, 2014 
Total Revenue ($000) 
1,623 
3,204 
2,664 
Q2, 2012 
Q2, 2013 
Q2, 2014 
Clinical Volume (Tests Processed) 
Combined CGI & Gentris Revenue
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 31 
Summary Statement of Operations (1st Half Comparison 2012-2014) 
Income Statement Item 
1H, 2012 
1H, 2013 
1H, 2014 
Combined 1H, 2014* 
Revenue 
$1,983 
$3,050 
$2,942 
$6,508 
Gross Profit 
74 
701 
149 
1,781 
Gross Margin (%) 
3.7% 
23.0% 
5.1% 
27.4% 
Research & Development (R&D) 
1,050 
951 
1,703 
2,043 
Sales & Marketing (S&M) 
716 
832 
1,667 
1,703 
General & Administrative (G&A) 
2,329 
2,961 
5,127 
7,092 
Operating Profit (Loss) 
(4,021) 
(4,043) 
(8,348) 
(9,056) 
Net Income (Loss) 
(2,933) 
(6,782) 
(6,673) 
(7,417) 
$ in thousands 
* The “Combined 1H, 2014” results are the aggregation of first half 2014 of both Cancer Genetics, Inc. and Gentris Corporation. The amounts may not be indicative of future results. 
Actual 06/30/14 
All Cash* 
$43,418 
Stockholders’ Equity 
40,463 
$ in thousands * All cash included $6,000 restricted to collateralize a credit line 
Balance Sheet Information
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 32 
Consistent Focus on Gross Profit Improvements Additional Efforts Focused Operationally in US & India 
Gross Profit Margin 
Highlights of Initiatives 
(52%) 
(39%) 
(3%) 
9% 
26% 
(1,000) 
(800) 
(600) 
(400) 
(200) 
0 
200 
400 
600 
800 
2009 
2010 
2011 
2012 
2013 
$ in Thousands 
Decrease CGI Costs for Development & Services 
Migrate DNA manufacture and NT Kits for CGI probes 
Develop remove G-Band analysis capability 
Develop remote FHACT® analysis capabilities 
Move entire probe manufacturing & assembly
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 33 
Multiple Customer Types Provide Diversified Revenue Mix With Covered Lives Already in Place 
Selected Payors 
Direct Bill Customer Types 
Biotechs 
Pharmas 
Academic 
Cancer Facilities 
Community & 
Regional Labs 
72+ million covered lives through multiple payors: 
18% 
21% 
58% 
3% 
Medicare 
3rd Party Insurance 
Companies, 
Hospitals 
& Care 
Facilities 
Payor Revenue Mix 1H, 2014 
Reimbursement Based 
Direct Bill / Pay Based 
3rd Party Insurance 
Medicare 
1H, 2014 
Probes 
Companies, Hospitals 
& Care Facilities
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 34 
Experienced and Focused Management and Boards 
Scientific Advisory Board 
Andrea Califano, Ph.D. 
Chairman of the Columbia Initiative for Systems Biology 
Associate Director for Bioinformatics, Herbert Irving Comprehensive Cancer Ctr 
Timothy A. Chan, M.D., Ph.D. 
Principal Investigator, Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center 
Riccardo Dalla-Favera, M.D. 
Director, Institute for Cancer Genetics at Columbia University 
Vundavalli V. Murty, Ph.D. 
Director, Cancer Cytogenetic Laboratory and Molecular Pathology at Columbia University 
Hans-Guido Wendel, M.D. 
Principal Investigator, Cancer Genetics Laboratory at Memorial Sloan-Kettering Cancer Center 
Howard McLeod, PharmD 
Medical Director, DeBartolo Family Personalized Medicine Institute, Moffitt Cancer Center 
Andrew D. Zelenetz, M.D., Ph.D. 
Chief of Lymphoma Service and Head of Molecular Hemo-Oncology Laboratory, Department of Medicine at MSKCC 
Raju Chaganti, Ph.D., FACMG Founder 
•35+ years in cancer research; 38 at MSKCC 
•Major discoveries in cancer genomics 
•Published 350+ articles, 4 patents 
Panna Sharma President & CEO 
•15+ years as advisor to global life science & healthcare cos. 
•Founded TSG Partners 
•Chief Strategy Officer, iXL (IIXL) 
Edward J. Sitar Chief Financial Officer & Treasurer 
•30+ yrs in finance & deal making in the healthcare industry 
•Healthagen, ActiveHealth Management, Cadent Holding, MIM Corporation (Bioscrip), Vital Signs, Zenith/Goldline Pharmaceutical, Coopers & Lybrand 
Jane Houldsworth, Ph.D. Vice President of R&D 
•25+ years in translational oncology research 
•Published 50+ articles, 4 patents 
•NIH grantee 
Chairman of the Board, 
| 
Keith Brownlie, CPA 
| 
Edmund Cannon 
| 
Raju Chaganti, Ph.D. 
John Pappajohn 
| 
Franklyn Prendergast, M.D., Ph.D. 
| 
Paul Rothman, M.D. 
| 
Panna Sharma 
Board of Directors 
Officers & Management Team
2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 35 
Consistent Achievement of Milestones Expected in Coming Quarters 
Increasing covered lives market access through additional payers & health care organizations 
Launching multi-marker NGS panel for lymphoid malignancies 
Additional international agreements with life science tools companies for DNA Probes and product distribution in key geographies 
MatBA® – Next phase of data and results from Dana Farber and HUMC studies to help support value and reimbursement 
Pursuing CE approval for IVDD use of FHACT® in E.U. 
Additional news on biopharma partners & relationships 
Pursuing additional indications for UroGenRA®-Kidney microarray 
Close of BioServe transaction (Q3, 2014) 
Migrated DNA-FISH Probe Manufacturing to India reducing cost, increasing capacity and improving operational flexibility 
Launched UroGenRA®-Kidney, a unique microarray for kidney cancer diagnosis in collaboration with MSKCC 
Collaborative Study of UroGenRA®-Kidney with Cleveland Clinic demonstrated 93% diagnostic accuracy – announced results at the AACR 105th Annual Meeting 
Launched FHACT® outside the U.S. in collaboration with the National Cancer Institute research publication and in the U.S. as an LDT under CLIA 
Promoted FHACT® at the ACOG Annual Meeting 
Received CLIA Approval for MatBA®-MCL (Mantle Cell Lymphoma) 
Finalized Agreement with Multiplan and Three Rivers which gave us access to 72+ million covered lives 
Launched OncoSpire Genomics – A Next Generation Sequencing Joint Venture with Mayo Clinic and announced initial set of projects (lung cancer, multiple myeloma & follicular lymphoma) 
Launched CALR Mutation Test – for the diagnosis of myeloproliferative neoplasms potentially evolving into acute leukemia 
Announced Multi-Year PathAdvantage Collaboration – for FHACT® (cervical cancer) 
Partnered with AstraZeneca – CGI will provide biomarker-based Dx in Central America and the Caribbean 
Acquisition of Gentris Corporation – closed on July 16, 2014 
Recent 
Accomplishments 
Upcoming Milestones and Value Drivers
For further information, please contact us at ir@cgix.com 
Cancer Genetics, Inc. 
Meadows Office Complex 
201 Route 17 North 
Rutherford, NJ 07070 
(201) 528-9200 
www.cancergenetics.com 
100214

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Cgix investor presentation Oct 2014

  • 1. Empowering Personalized Cancer Treatment October 2014
  • 2. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 2 Forward-Looking Statement This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements pertaining to future financial and/or operating results, future growth in research, technology, clinical development and potential opportunities for Cancer Genetics, Inc. products and services or Gentris, Inc. products and services, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to, statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, risks of cancellation of customer contracts or discontinuance of trials, risks related to integration of the acquisitions of Gentris and BioServe and the realization of the currently anticipated benefits, uncertainty in the results of clinical trials or regulatory approvals, need and ability to obtain future capital, maintenance of intellectual property rights and other risks discussed in the Company's Form 10-K for the year ended December 31, 2013 and 10-Q for the quarter ended June 30, 2014 along with other filings with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. Cancer Genetics disclaims any obligation to update these forward-looking statements.
  • 3. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 3 Focused On Personalizing Cancer Diagnosis and Treatment Globally Through Genomics  Develop & Commercialize Unique Targeted Panels For The Comprehensive Assessment of Cancer  Develop Compelling Collaborations With Leading Institutions To Support Genomic Test Adoption, Validation & Health Economics  Establish Sales, Marketing & Commercial Infrastructure In US & India  Serve Both the Clinical and Biopharma Communities Leveraging A Standardized Global Infrastructure  Selectively Acquire Companies & Capabilities That Further Our Mission of Impacting The Personalization of Cancer Diagnosis & Management
  • 4. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 4 Molecular Diagnostics are Changing our Understanding of Cancer While Providing New Tools to Diagnose & Treat Patients Our unique focus & approach supports the entire cancer care continuum Personalize therapeutic plan and treatment options DIAGNOSIS PROGNOSIS THERANOSIS Assist in patient outcome and disease management What drug(s) to give, how much, and when? What are my survival prospects? Do I have cancer and what type? Use genomics to provide an accurate and definitive typing of the cancer Proprietary Products Focused Oncology Lab Comprehensive Report Integrated Molecular Diagnostic Testing Brings Benefits Across the Entire Oncology Ecosystem
  • 5. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 5 CGI’s Mission is to Personalize and Improve the Success Rate in Cancer Treatment Integrating & Delivering Genomic Information About a Patient’s Cancer Can Improve Care & Reduce Cost Phenotypic & Physical Examination Morphologic & Pathological Analysis Large & Multiple Specimens Required Significant Delays to Treatment Traditional Approach Biomarkers and Companion Diagnostics Genomic Analysis & Proprietary Algorithms Reduced Size and Number of Specimens Improved Diagnoses & Treatment Plans Our Approach: Personalized Medicine Target For Tomorrow 25% Situation Today Source: Clinical Trends in Molecular Medicine, Vol. 7, Issue 5 100% Success Rate Target Success Rate
  • 6. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 6 The Acquisitions of BioServe India and Gentris Corporation Provide Significant Market Upside & Improve CGI’s Competitive Position •Growth potential in integrating our oncology- focused testing capabilities with Gentris’ high-value contracts. •Expansion of Gentris’ capabilities and portfolio to include oncology-focused pharmacogenomics services. •24,000 sq. foot lab space (CLIA/CAP/GLP) with NGS, genotyping, and gene expression test capabilities. Gentris Corporation [Closed 7/16/14] •Access to high-growth Indian diagnostics market – projected to grow at 15-20% per annum for the next decade. •Accelerates next-generation sequencing development and validation of targeted hot spot oncology panels. •Cost-effective expansion of genomic analysis & informatics capabilities with state of-the-art 14,000 sq. foot lab. BioServe India [Closed 8/18/14]
  • 7. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 7 Our Expansion is Crucial for our Global Positioning as an Industry Leader in Genomics Testing and Services Clinical Services and R&D 82 Employees as of July 1st CGI is positioned as leader in oncology-focused genomics and is enabled to deliver complete solutions to the clinical and research communities. Clinical & Research Services Addition of 33 employees Pharmacogenomics Services Addition of 41 employees
  • 8. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 8 Unique, Scalable and Multifaceted Business Model With A Focus On Providing A Complete Solution Suite of Products and Services Provides Multiple Growth Drivers and Value to Multiple Parties: Clinical Community, Biopharma & Medtech CLINICAL SERVICES Differentiated and complete disease-focused solutions Superior turnaround times World-class expertise in genomics and cytogenetics Serving community hospitals and labs through unique Expand Dx™ program BIOPHARMA PARTNERSHIPS Biomarker and companion diagnostic development World-class genomics and bioinformatics Drug-specific and cancer-specific assays Comprehensive focus in hematologic & urogenital cancers PROPRIETARY PRODUCTS Proprietary molecular diagnostics & FISH probes Clinically validated IP-protected Sold globally Probe manufacturing leverages low-cost, high scale facility in India
  • 9. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 9 Our Target Markets in Oncology Testing Comprise Over 615,000 New Lives Annually in the U.S. Ability to Impact Over 615,000 New Lives Annually in the U.S. Source: American Cancer Society 156,420 2014 Estimated New Cases (U.S.) Death Rate 35% Hematological: Lymphoma, Leukemia, M. Myeloma 371,610 2014 Estimated New Cases (U.S.) Death Rate 16% Urogenital: Kidney, Bladder & Prostate 86,970 2014 Estimated New Cases (U.S.) Death Rate 31% Gynecological: Cervical, Endometrial & Ovarian 6 Products Launched in Target Segments Over $6Bn in Annual U.S. Spend on Lab Testing In These Categories
  • 10. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 10 6 Proprietary Diagnostic Products Commercially Launched & In Market Incidence Indication Hematologic Cancers 106,770 (Annual New Cases, Global) Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma 142,360 (Annual New Cases, Global) Diffuse Large B-Cell Lymphoma 62,300 (Annual New Cases, Global) Follicular Lymphoma 17,795 (Annual New Cases, Global) Mantle Cell Lymphoma Urogenital Cancers 274,000 (Annual New Cases, Global) Kidney Cancer HPV-Associated Cancers (FHACT®) 1,750,000 (Annual New Cases, US) HPV+ Low Grade Cervical Lesions Over 2.3 Mn Combined Annual New Cases Globally
  • 11. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 11 Product Pipeline Research & Discovery Clinical Development Commercial Development Launch & Market Entry Indication Development Stage Hematologic Cancers Multiple Myeloma Comprehensive Myeloid Panel [NGS-based] Comprehensive CLL Panel [NGS-based] UroGenital Cancers Bladder Cancer Comprehensive Renal Panel [NGS-based] Cervical Cancer HPV-Associated Cancers (FHACT®) Head & Neck Cancer
  • 12. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 12 Despite Improved Cancer Care, Case Numbers for Hematologic Cancers are Still Rising Genomics-Based Tests like MatBA® are Critical and Improve the Management and Cost of Hematologic Cancers Source: Genzyme & Nature Source: National Cancer Institute, National Center for Health Statistics, SEER Dataset of Incidence & Mortality, FDA 1 2 5 12 89 100 80 60 30 2 Number of Years Ago 11.1 12.6 15.5 18.5 20.0 19.7 20.5 21.2 5.6 6.2 7.1 7.9 8.7 8.2 6.9 7.3 1975 1980 1985 1990 1995 2000 2005 2010 Incidence Rate Survival Rate Identified Leukemia & Lymphoma Subtypes Incidence & Survival Rates for NHLs (US Only, per 100,000)
  • 13. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 13 MatBA®-CLL/SLL Improves Risk Stratification & Outcome Prediction Validated in Collaboration w/ Dr. Kanti Rai & Dr. Nicholas Chiorazzi (NSLIJ); 2 Datasets, 322 specimens Additional Validations being conducted w/ HUMC & Dana Farber; 2 Cohorts, 350+ specimens █ Favorable █ Intermediate █ Unfavorable █ Favorable/ Intermediate (no distinction) 38% of cases in our study have a favorable prognosis falling under "watch & wait" approach. 8% of cases with unfavorable prognosis missed by FISH and caught using MatBA®-CLL/SLL. Impact on therapy selection & clinical management of CLL patients. Genomic Aberrations Reported by FISH: 4 Genomic Aberrations Reported by MatBA®-CLL/SLL: 20 85% 15% FISH 23% 39% 38% (Current Method) (CGI Method)
  • 14. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 14 MatBA® can Group Patients into Risk Groups & Prognostication Classes MatBA®- CLL / SLL is a diagnostic tool and prognostic indicator for patient stratification and improved patient management Being actively used in clinical care, in clinical trials and in validation programs with Dana Farber, MSKCC and HUMC 20 key genetic events/sites classify CLL patients as having the potential for Poor outcome = High risk Intermediate outcome = Intermediate risk Good outcome = Low risk Detection of specific genomic imbalance in CLL/SLL by MatBA®-CLL/SLL correlates patient risk with time to first treatment (TTFT) and shorter overall survival (OS) Patients classified as high risk showed a shorter TTFT compared to those classified as low or intermediate risk Patients classified as high risk had significantly shorter OS times than those classified as low or intermediate risk Provides additional risk stratification between low and intermediate risk patients, not currently available in other tests Time to First Treatment (TTFT) Time (months) Time (months) Proportion Surviving Proportion Treatment- Free – GOOD (n=74) – INTERMED (n=107) – POOR (n=47) – GOOD (n=74) – INTERMED (n=107) – POOR (n=47) P = 0.090 P = 0.001 P < 0.001 P = 0.010 Overall Survival (OS) Leukemia & Lymphoma – Houldsworth, et. al Sept. 18, 2013
  • 15. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 15 UroGenRA®-Kidney Can Guide Management of Patients with Renal Masses and Appropriate Treatment Selection Clinical Benefits Include Reduction in Number of Highly Invasive Procedures and Time to Treatment Initiation, and Better Informed Treatment Selection Development of diagnostic algorithm >600 RCC malignant subtypes (in-silico: SNP) >100 malignant and benign renal neoplasms (in-house: aCGH & FISH) Retrospective in-house FFPE validation (n>190) CCF 100% diagnostic yield 97% diagnostic sensitivity to distinguish benign from malignant renal neoplasms 93% sensitivity to distinguish malignant RCC subtypes C. Magi-Galluzzi and E. Klein (Cleveland Clinic) Prospective ongoing percutaneous core needle biopsy (n>50) MSKCC Demonstrated ability to diagnose pathologically “unclassifiable” biopsies prior to surgical intervention J. Coleman and J. Durack (MSKCC) PROBLEM Men and women with renal masses often undergo unnecessary nephrectomy for accurate diagnosis and experience delay in treatment SOLUTION UroGenRA® will detect genomic aberrations in a single assay permitting accurate diagnosis (benign vs malignant, and malignant subtype) guiding appropriate management and treatment strategies
  • 16. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 16 FHACT® - A New Genomic Aid In The Screening & Management Of Cervical Cancer FHACT® Provides Critical Information Which Reduces Unnecessary and Costly Colposcopies Cervical cancer effects nearly 500,000 women globally each year with nearly 80% in developing countries. Today, all these women are referred for colposcopy. Women with abnormal or unclear Pap smears 55 Million Pap smears per year 3.5 Million Pap smears come back as unclear/abnormal 2 Million biopsies performed 12,000 cases of cervical cancer
  • 17. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 17 FHACT® Provides Information for Developing Treatment Plans Potentially Reducing Healthcare Costs & Procedures FHACT® is the Only 4 Color FISH Probe that can be Used for Cervical Cancer Screening as Additional Testing Before Referral for Colposcopy Global Validation Partners Genomic Amplification by Disease Category Source: P. Luhn, J. Houldsworth, et al., Gynecologic Oncology (2013) 5 10 19 20 0 20 40 60 80 ptrend = 0.01 6 9 9 20 0 20 40 60 80 ptrend = 0.02 6 9 7 12 0 20 40 60 80 ptrend = 0.03 3 8 12 12 0 20 40 60 ptrend = 0.001 <CIN2 & NLIM (n=11) <CIN2 & LSIL (n=20) CIN2 &/or HSIL (n=10) CIN3+ (n=7) <CIN2 & NLIM (n=11) <CIN2 & LSIL (n=20) CIN2 &/or HSIL (n=10) CIN3+ (n=7) FHACT® detects irreversible changes in cervical cells caused by HPV.
  • 18. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 18 IP Position and Detailed Global Strategy Strong and growing portfolio in molecular-focused patents for disease identification and stratification IP-based on unique algorithms across a broad group of chromosomal regions Validation of specific clinical endpoints that are associated with particular disease outcomes or decisions Filing and maintenance of trademark portfolio Tool for Diagnosis and Prognosis of Mature B-Cell Neoplasms US Issued Patent 8,580,713 US Issued Patent 8,557,747 Europe 10803548.6 India 6657/DELNP/2012 Canada 2,785,656 Methods of Analyzing Chromosomal Translocations Using Fluorescence In Situ Hybridization (FISH) US Issued Patent 7,585,964 US Issued Patent 7,964,345 Canada 2,447,320 Panel for the Detection and Differentiation of Renal Cortical Neoplasms US Issued Patent 8,603,948 US 14/078,726 Europe 08844570.5 Methods for Detecting Human Papilloma Virus-Associated Cancers US 13/227,027 US 13/474,111 PCT/US2011/050681 Methods and Tools for the Diagnosis of Female Gynecological Cancers and Precancers US 61/581,350
  • 19. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 19 Large, Targeted Market Opportunities Target Markets Commercialization Strategy Community Hospitals Regional Cancer Centers Oncologists and Pathologists Continue to growing sales force that calls on hospitals and regional laboratories Plan development of national footprint through Expand Dx™ Biotechnology Companies Pharmaceutical Companies Leverage clinical infrastructure and proprietary product portfolio for testing services that support clinical trials Expand sales emphasis of Select One® Emerging Markets Enhance distributor base in select emerging economies Partner with leading local cancer care providers and hospitals to provide probes, arrays and clinical services Collaborate to create and validate microarrays and other proprietary products Accelerate launch of large scale studies Universities and Research Centers
  • 20. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 20 Unique Service Offering Developed to Enable Community Hospitals to Improve Cancer Outcomes & Treat Patients Locally Delivers better outcomes to community hospitals and laboratories Enables community hospitals to bring “state-of-the-art” genomic testing to patients Brings personalized medicine to the community hospital vs. just at academic and teaching hospitals Allows community hospitals to keep patients and treat them locally Improving care and quality is critical to maintaining reimbursement for community hospitals $600,000 - $800,000 USD in Testing Opportunity on Average per Hospital Expanding & Developing Cancer Care is a Top Priority for Hospital CEOs & CFOs 4,000 to 5,000 Community Hospitals & Laboratories in the U.S. 85% Of All U.S. Cancer Patients are Initially Diagnosed in Community Hospitals & Laboratories
  • 21. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 21 Through Acquisition, Clinical Trial Services Show Strong Growth and Robust Pipeline Gentris Provides Pharmacogenomic Clinical Trial Services to Several Large Pharma Companies Including Merck, Novartis, Otsuka, Eisai and Bristol-Myers Squibb GROWTH IN CGI’s SELECT ONE® CONTRACTS ($000) 21% 55% ONCOLOGY DRUGS ASSOCIATED WITH BIOMARKER(S) $300 $2,700 $8,500 $18,000 2011 2012 2013 2014 Approximate value of contracts with biotech and pharma clients 2011 2016 Source: Company Analysis and Management Estimates
  • 22. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 22 Over 6,800 Oncology Trials in the US Aligned with our Core Markets Number of Open Clinical Trials (U.S.) 1,439 1,453 2,178 1,765 Lymphoma Leukemia Urogenital HPV-Associated Source: www.clinicaltrials.gov
  • 23. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 23 Gilead is Currently Using a Comprehensive Panel of CGI Services & Proprietary Products in National & International Trials for Hematologic Cancers The Gilead Relationship Exemplifies the Significant Upside Potential of CGI’s Select One® Offering Highlights Comprehensive, biomarker-based patient profiling will help risk stratification and response monitoring Improved patient profiling will result in improved trial efficacy for Gilead Testing will occur across several methodologies, including flow cytometry, FISH, sequencing and mutation assays, and MatBA® microarrays CGI provides biomarker driven insight regarding patient targeting and potential outcomes Trials cover both national and international locations with all patient specimens being processed in Rutherford, New Jersey CGIX Press Release: Cancer Genetics, Inc. Selected By Gilead Sciences, Inc. to Provide Clinical Trial Services for International Trials in Chronic Lymphocytic Leukemia
  • 24. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 24 Roche Partnership Expanding Market Presence Internationally “By expanding our relationship, we are strengthening our ability to provide patients the best service possible.” Alvaro Soto, Roche Servicios, Central America & Caribbean General Manager Highlights CGI provides genomic and biomarker testing services to 14 countries in Central America and the Caribbean. CGI won a global RFP to help a strategic personalized medicine initiative for Roche Servicios (Latin America) Roche sends all patient samples to the Rutherford facility where they are catalogued and processed CGI interacts with both Roche and the hospital staff (pathologists, oncologists and nurses) and supports delivery of reports through an online HIPAA compliant portal CGI and Roche expanded this relationship in 2013 and will begin developing workshops and training programs to drive adoption of biomarker-based cancer diagnostics throughout Central America and the Caribbean CGI and Roche recently further expanded this relationship with an exclusive multi-year deal in which CGI will develop a center of excellence for lung cancer testing utilizing Roche’s FDA-Approved cobas® platform CGIX Press Release: Cancer Genetics, Inc. selected by Roche Servicios S.A. to provide services for the diagnosis and personalization of oncology treatment CGIX Press Release: Cancer Genetics, Inc. expands relationship with Roche Servicios S.A.
  • 25. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 25 AstraZeneca Partnership A Testament to the Growing Global Awareness of the Value of the CGI Brand “We chose to partner with Cancer Genetics in this endeavor because of their experience in biomarker-based diagnostic testing and their commitment to delivering timely and accurate results to healthcare professionals and patients.” Rodrigo Fernandez, Country President of AstraZeneca CAMCAR, S.A. Highlights CGI will provide biomarker and molecular based testing services focused on select oncology categories and trials Services include complex testing for diagnosis and prognosis of cancer patients in Central America and the Caribbean CGI will work in close conjunction with AstraZeneca on exploring expansion opportunities into additional geographic territories, further oncology categories, and into select oncology trials The partnership will concentrate on multiple cancer categories, with lung cancer being an initial area of focus CGIX Press Release: Cancer Genetics, Inc. Announces Partnership with AstraZeneca to Provide Biomarker & Molecular Based Testing
  • 26. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 26 Collaborations with Premier Cancer Research Institutions Leading Differentiated Research & Driving Product Adoption Research Collaboration/ Licensing Clinical Services Partnership Highlights   Kidney Cancer, DLBCL, MCL & FL  Joint Venture Focused on Oncology & Next Generation Sequencing  Cervical Cancer  DLBCL   CLL   Cervical Cancer & DLBCL  Cervical Cancer  Kidney Cancer   DLBCL, Head & Neck Cancers   CLL
  • 27. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 27 Mayo Clinic Joint Venture Investing in the Future – OncoSpire Genomics The Value and Focus of Next Generation Sequencing is Moving from Platforms to Clinically Relevant, Disease-Specific Applications Highlights JV, based in Rochester, MN, will develop clinical diagnostic products and services on NGS platform(s) in areas of high clinical need Three initial projects in key oncology categories selected by the SRC (Scientific Review Committee): Lung Cancer, Multiple Myeloma, Follicular Lymphoma CGI commits up to $6 M over initial three year period (2013 to 2015-16 expected) Mayo commits to “in-kind” services and support, use of facilities, NGS capabilities and access to biorepository Joint Venture is exclusive in the project areas selected by CGI & Mayo Important company update and analyst day held November 22, 2013 Next Generation Sequencing in Oncology
  • 28. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 28 OncoSpire Genomics Projects are Unique and Have High Value 1.6 million new cases 200,000 new cases 20,920 new cases Informed Discovery Clinical Development Commercial Development Market Entry (with partners) Lung Cancer Multiple Myeloma Follicular Lymphoma Selected Projects Have Significant Clinical Value & May Yield Multiple Focused Panels to Become the Standard of Care in NGS-Based Oncology Management
  • 29. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 29 Strong History of Growth CGI Revenue & Clinical Volume Trends (2009 – 2013) 54% Full Year 2013 Revenue Growth $1.67 $2.52 $3.02 $4.30 $6.61 2009 2010 2011 2012 2013 2,321 3,146 3,622 6,610 10,771 2009 2010 2011 2012 2013 Total Revenue ($Mn) Clinical Volume (Tests Processed)
  • 30. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 30 Strong History of Growth - Revenue & Clinical Volume Trends (Q2 Comparison 2012-2014) $1,148 $1,832 $3,231 Q2, 2012 Q2, 2013 Q2, 2014 Total Revenue ($000) 1,623 3,204 2,664 Q2, 2012 Q2, 2013 Q2, 2014 Clinical Volume (Tests Processed) Combined CGI & Gentris Revenue
  • 31. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 31 Summary Statement of Operations (1st Half Comparison 2012-2014) Income Statement Item 1H, 2012 1H, 2013 1H, 2014 Combined 1H, 2014* Revenue $1,983 $3,050 $2,942 $6,508 Gross Profit 74 701 149 1,781 Gross Margin (%) 3.7% 23.0% 5.1% 27.4% Research & Development (R&D) 1,050 951 1,703 2,043 Sales & Marketing (S&M) 716 832 1,667 1,703 General & Administrative (G&A) 2,329 2,961 5,127 7,092 Operating Profit (Loss) (4,021) (4,043) (8,348) (9,056) Net Income (Loss) (2,933) (6,782) (6,673) (7,417) $ in thousands * The “Combined 1H, 2014” results are the aggregation of first half 2014 of both Cancer Genetics, Inc. and Gentris Corporation. The amounts may not be indicative of future results. Actual 06/30/14 All Cash* $43,418 Stockholders’ Equity 40,463 $ in thousands * All cash included $6,000 restricted to collateralize a credit line Balance Sheet Information
  • 32. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 32 Consistent Focus on Gross Profit Improvements Additional Efforts Focused Operationally in US & India Gross Profit Margin Highlights of Initiatives (52%) (39%) (3%) 9% 26% (1,000) (800) (600) (400) (200) 0 200 400 600 800 2009 2010 2011 2012 2013 $ in Thousands Decrease CGI Costs for Development & Services Migrate DNA manufacture and NT Kits for CGI probes Develop remove G-Band analysis capability Develop remote FHACT® analysis capabilities Move entire probe manufacturing & assembly
  • 33. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 33 Multiple Customer Types Provide Diversified Revenue Mix With Covered Lives Already in Place Selected Payors Direct Bill Customer Types Biotechs Pharmas Academic Cancer Facilities Community & Regional Labs 72+ million covered lives through multiple payors: 18% 21% 58% 3% Medicare 3rd Party Insurance Companies, Hospitals & Care Facilities Payor Revenue Mix 1H, 2014 Reimbursement Based Direct Bill / Pay Based 3rd Party Insurance Medicare 1H, 2014 Probes Companies, Hospitals & Care Facilities
  • 34. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 34 Experienced and Focused Management and Boards Scientific Advisory Board Andrea Califano, Ph.D. Chairman of the Columbia Initiative for Systems Biology Associate Director for Bioinformatics, Herbert Irving Comprehensive Cancer Ctr Timothy A. Chan, M.D., Ph.D. Principal Investigator, Human Oncology and Pathogenesis Program at Memorial Sloan-Kettering Cancer Center Riccardo Dalla-Favera, M.D. Director, Institute for Cancer Genetics at Columbia University Vundavalli V. Murty, Ph.D. Director, Cancer Cytogenetic Laboratory and Molecular Pathology at Columbia University Hans-Guido Wendel, M.D. Principal Investigator, Cancer Genetics Laboratory at Memorial Sloan-Kettering Cancer Center Howard McLeod, PharmD Medical Director, DeBartolo Family Personalized Medicine Institute, Moffitt Cancer Center Andrew D. Zelenetz, M.D., Ph.D. Chief of Lymphoma Service and Head of Molecular Hemo-Oncology Laboratory, Department of Medicine at MSKCC Raju Chaganti, Ph.D., FACMG Founder •35+ years in cancer research; 38 at MSKCC •Major discoveries in cancer genomics •Published 350+ articles, 4 patents Panna Sharma President & CEO •15+ years as advisor to global life science & healthcare cos. •Founded TSG Partners •Chief Strategy Officer, iXL (IIXL) Edward J. Sitar Chief Financial Officer & Treasurer •30+ yrs in finance & deal making in the healthcare industry •Healthagen, ActiveHealth Management, Cadent Holding, MIM Corporation (Bioscrip), Vital Signs, Zenith/Goldline Pharmaceutical, Coopers & Lybrand Jane Houldsworth, Ph.D. Vice President of R&D •25+ years in translational oncology research •Published 50+ articles, 4 patents •NIH grantee Chairman of the Board, | Keith Brownlie, CPA | Edmund Cannon | Raju Chaganti, Ph.D. John Pappajohn | Franklyn Prendergast, M.D., Ph.D. | Paul Rothman, M.D. | Panna Sharma Board of Directors Officers & Management Team
  • 35. 2014 Cancer Genetics, Inc. | NASDAQ: CGIX | 35 Consistent Achievement of Milestones Expected in Coming Quarters Increasing covered lives market access through additional payers & health care organizations Launching multi-marker NGS panel for lymphoid malignancies Additional international agreements with life science tools companies for DNA Probes and product distribution in key geographies MatBA® – Next phase of data and results from Dana Farber and HUMC studies to help support value and reimbursement Pursuing CE approval for IVDD use of FHACT® in E.U. Additional news on biopharma partners & relationships Pursuing additional indications for UroGenRA®-Kidney microarray Close of BioServe transaction (Q3, 2014) Migrated DNA-FISH Probe Manufacturing to India reducing cost, increasing capacity and improving operational flexibility Launched UroGenRA®-Kidney, a unique microarray for kidney cancer diagnosis in collaboration with MSKCC Collaborative Study of UroGenRA®-Kidney with Cleveland Clinic demonstrated 93% diagnostic accuracy – announced results at the AACR 105th Annual Meeting Launched FHACT® outside the U.S. in collaboration with the National Cancer Institute research publication and in the U.S. as an LDT under CLIA Promoted FHACT® at the ACOG Annual Meeting Received CLIA Approval for MatBA®-MCL (Mantle Cell Lymphoma) Finalized Agreement with Multiplan and Three Rivers which gave us access to 72+ million covered lives Launched OncoSpire Genomics – A Next Generation Sequencing Joint Venture with Mayo Clinic and announced initial set of projects (lung cancer, multiple myeloma & follicular lymphoma) Launched CALR Mutation Test – for the diagnosis of myeloproliferative neoplasms potentially evolving into acute leukemia Announced Multi-Year PathAdvantage Collaboration – for FHACT® (cervical cancer) Partnered with AstraZeneca – CGI will provide biomarker-based Dx in Central America and the Caribbean Acquisition of Gentris Corporation – closed on July 16, 2014 Recent Accomplishments Upcoming Milestones and Value Drivers
  • 36. For further information, please contact us at ir@cgix.com Cancer Genetics, Inc. Meadows Office Complex 201 Route 17 North Rutherford, NJ 07070 (201) 528-9200 www.cancergenetics.com 100214