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KROMOSOM 17 & KROMOSOM 18 KELOMPOK 9 Rizqiani Amalia Kusumasari Satrio Wicaksono Samuel Sandy Siti Ruqayyah
CHARACTERISTICS  ,[object Object],[object Object],[object Object],[object Object]
Cont’d ,[object Object],[object Object]
Jenis-jenis kelainan terkait kromosom 17 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Genes  on chromosome 17 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Changes in conditions of Chr-17 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Scheme of  acute promyelocytic leukemia ,[object Object],[object Object],[object Object],RARα a protein    tumor suppressor blood cells are stuck at the promyelocyte stage, and they proliferate abnormally. Excess promyelocytes accumulate in the bone marrow and normal white blood cells cannot form, leading to acute promyelocytic leukemia.
[object Object],[object Object],[object Object],CHARACTERISTICS
Cont’d Normal chromosome 18
Major conditions changes in chr-18 18 p- There is a missing piece from the short arm of chromosome 18. 18q- There is a missing piece from the long arm of chromosome 18.  If the missing piece is close to the centromere, it is called proximal 18q-.  If the missing piece is close to the end of the chromosome, it is called distal 18q-.
Major conditions changes in chr-18 Ring 18 One of the copies of chromosome 18 forms a ring, and material is lost from both the long and short arm. Tetrasomy 18p An extra chromosome is present. This chromosome is made up of two copies of the short arm of chromosome 18.
Major conditions changes in chr-18 Trisomy 18 There are three copies instead of the usual two.
Genes on chromosome 18 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Jenis-jenis kelainan terkait kromosom 18 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Changes in conditions of Chr-18
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pitt-Hopkins Syndrome (PTHS)
[object Object],[object Object],[object Object],[object Object],[object Object]

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Kromosom 17 & 18

  • 1. KROMOSOM 17 & KROMOSOM 18 KELOMPOK 9 Rizqiani Amalia Kusumasari Satrio Wicaksono Samuel Sandy Siti Ruqayyah
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7.
  • 8.
  • 10. Major conditions changes in chr-18 18 p- There is a missing piece from the short arm of chromosome 18. 18q- There is a missing piece from the long arm of chromosome 18.  If the missing piece is close to the centromere, it is called proximal 18q-.  If the missing piece is close to the end of the chromosome, it is called distal 18q-.
  • 11. Major conditions changes in chr-18 Ring 18 One of the copies of chromosome 18 forms a ring, and material is lost from both the long and short arm. Tetrasomy 18p An extra chromosome is present. This chromosome is made up of two copies of the short arm of chromosome 18.
  • 12. Major conditions changes in chr-18 Trisomy 18 There are three copies instead of the usual two.
  • 13.
  • 14.
  • 15.
  • 16.
  • 18.