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Getting Published in Science

      Professor David Male
Why do you publish ?
• If you do not publish, no-one knows what you have done
• Publications are a key component of your CV

•   A laboratory needs to publish, in order to get funding
•   Writing papers is a good basis for writing a thesis
•   Planning for a paper is a good way to plan experiments
•   Referees often provide useful advice on what is expected
Where do you publish ?
• Academic Journals – Peer reviewed
  – Print and electronic (sometimes require payment)
  – Electronic, open access (usually requires payment)

• Books/ Review articles (sometimes commissioned)
• Conference abstracts (sometimes reviewed)
Authors

• First author – the person who has done the most lab-work
  or fieldwork and produced the most figures/tables of data.
• Last author – the project director ie the person who has
  got the money (PI).
• Middle authors – people who have contributed data or
  unique reagents.

• Corresponding author – the person that submits the
  paper and communicates with the journal.

 However the normal practice varies between subjects
The actual author(s)

• Usually the first author, but it may be the PI with
  contributions from other authors


 All authors are jointly responsible for the publication
 All authors should have read all of the manuscript and agreed to it before
 submission
 All authors should be able to answer questions on the paper if they are asked
 to do so – eg at a meeting.
When are you ready to publish ?

• Typically a PhD needs 2-3 publications (but it depends
  on the subject area)
• Needs to be a complete piece of work, not a progress
  report
• The level of detail in a publication is much less than in
  a thesis – background and pilot experiments are not
  usually included.
• Negative results are often difficult to publish unless
  they support positive findings, and they then require
  excellent positive controls.
A scientific paper has a narrative

• What you investigated and why      Introduction
• What other people think about
  this subject and why
• What are the key questions
• What you did                       Materials and methods
• What you saw                       Results
• How did you interpret your
  observations?
• How does it answer the questions   Discussion
• How does this relate to previous
  findings
Writing

  Abstract & Keywords

  Introduction            Selective editing       1st year report


     Methods

                                              Figures and legends
     Results            Narrative text
                                              Tables and footnotes

  Discussion

 Acknowledgements

 References
Title
• Sending signals: how bacteria communicate with plants

Or

The mechanisms of NodD1-mediated transcription at
 Nod gene promoters.



 Ten times more people will read the title than read the abstract
 Ten times more people will read the abstract than the paper
 ….give yourself the best chance.
Which Journal ?
• Chose Journal on the readership – what journals
  are in your reference list?

• Select by impact factor – quality generally counts for
  more than quantity. – impact factors are subject
  dependent.
• What type of publications do they accept?
  - rapid publications, short reports, standard papers


 Read the instructions for authors carefully
Writing the paper
• Start by reading CAREFULLY Journal regulations – or
  you will be rewriting after all other work.

• Word/page limit
• Number of figures - Black and white in print vs colour
  format (tif/jpg) resolution (dpi) fonts (size/consistency)
• Layout and headings, column widths
• Submission format – word/pdf/html
• References how labelled and recorded ?
Style: Active or passive

• We cultured the cells for 48h at 37°C.
• The cells were cultured for 48h at 37°C.

                      Be consistent


 The cells were cultured for 48h, after which we added the cytokine and
 the cells were then cultured for a further 48h, before extracting the
 nuclear proteins.
Tenses
• Species of the genus Eleonaceae were found in areas
  of highest humidity
• Species of the genus Eleonaceae are found in areas of
  highest humidity

              Be aware of what you are writing


  The particles were detected using a beta-counter and have energy 25mev.
  Macrophages are normally found in all tissues of the body, however we did
  not detect them in our samples.
  The compound was found to have a molecular weight of 187Da but it is not
  present in smoke from car tyres.
Avoid ambiguity

• The protein may be phosphorylated on amino acid
  serine-27 or serine-42.



  The protein is phosphorylated on either amino acid serine-27 or serine-42.
  The protein is phosphorylated on amino acid serine-27 and/or serine-42.
  The protein may be phosphorylated on either of these amino acids, but our
  results do not tell us which it is.
  Under specific conditions, either one or the other or both amino acids may
  become phosphorylated.
Qualified statements

• Qualify statements only once
• Aim for precision even in qualified statements

 The data may suggest that the molecular weight of the protein could be
 approximately 147kDa.
 The data indicate that the molecular weight of the protein is approximately
 147kDa.


The boiling point of the compound is approximately 67°C.
The boiling point of the compound is in the range 65.5°C - 68°C.
Response from the journal

• Many excellent papers are rejected – this is not an
  affront to your dignity or intelligence.
• Referees take a deal of time to review your paper –
  sometimes they get it wrong or fail to understand what
  you have written, but mostly their points are valid.
• Wait 24 hours before firing off a reply to the journal.
• Consult all of your fellow authors.
• Do what is asked, if it is reasonable…………..
• Make point by point responses when resubmitting.
Questions and discussion

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Getting Published in Science Tips

  • 1. Getting Published in Science Professor David Male
  • 2. Why do you publish ? • If you do not publish, no-one knows what you have done • Publications are a key component of your CV • A laboratory needs to publish, in order to get funding • Writing papers is a good basis for writing a thesis • Planning for a paper is a good way to plan experiments • Referees often provide useful advice on what is expected
  • 3. Where do you publish ? • Academic Journals – Peer reviewed – Print and electronic (sometimes require payment) – Electronic, open access (usually requires payment) • Books/ Review articles (sometimes commissioned) • Conference abstracts (sometimes reviewed)
  • 4.
  • 5. Authors • First author – the person who has done the most lab-work or fieldwork and produced the most figures/tables of data. • Last author – the project director ie the person who has got the money (PI). • Middle authors – people who have contributed data or unique reagents. • Corresponding author – the person that submits the paper and communicates with the journal. However the normal practice varies between subjects
  • 6. The actual author(s) • Usually the first author, but it may be the PI with contributions from other authors All authors are jointly responsible for the publication All authors should have read all of the manuscript and agreed to it before submission All authors should be able to answer questions on the paper if they are asked to do so – eg at a meeting.
  • 7. When are you ready to publish ? • Typically a PhD needs 2-3 publications (but it depends on the subject area) • Needs to be a complete piece of work, not a progress report • The level of detail in a publication is much less than in a thesis – background and pilot experiments are not usually included. • Negative results are often difficult to publish unless they support positive findings, and they then require excellent positive controls.
  • 8. A scientific paper has a narrative • What you investigated and why Introduction • What other people think about this subject and why • What are the key questions • What you did Materials and methods • What you saw Results • How did you interpret your observations? • How does it answer the questions Discussion • How does this relate to previous findings
  • 9. Writing Abstract & Keywords Introduction Selective editing 1st year report Methods Figures and legends Results Narrative text Tables and footnotes Discussion Acknowledgements References
  • 10. Title • Sending signals: how bacteria communicate with plants Or The mechanisms of NodD1-mediated transcription at Nod gene promoters. Ten times more people will read the title than read the abstract Ten times more people will read the abstract than the paper ….give yourself the best chance.
  • 11. Which Journal ? • Chose Journal on the readership – what journals are in your reference list? • Select by impact factor – quality generally counts for more than quantity. – impact factors are subject dependent. • What type of publications do they accept? - rapid publications, short reports, standard papers Read the instructions for authors carefully
  • 12. Writing the paper • Start by reading CAREFULLY Journal regulations – or you will be rewriting after all other work. • Word/page limit • Number of figures - Black and white in print vs colour format (tif/jpg) resolution (dpi) fonts (size/consistency) • Layout and headings, column widths • Submission format – word/pdf/html • References how labelled and recorded ?
  • 13. Style: Active or passive • We cultured the cells for 48h at 37°C. • The cells were cultured for 48h at 37°C. Be consistent The cells were cultured for 48h, after which we added the cytokine and the cells were then cultured for a further 48h, before extracting the nuclear proteins.
  • 14. Tenses • Species of the genus Eleonaceae were found in areas of highest humidity • Species of the genus Eleonaceae are found in areas of highest humidity Be aware of what you are writing The particles were detected using a beta-counter and have energy 25mev. Macrophages are normally found in all tissues of the body, however we did not detect them in our samples. The compound was found to have a molecular weight of 187Da but it is not present in smoke from car tyres.
  • 15. Avoid ambiguity • The protein may be phosphorylated on amino acid serine-27 or serine-42. The protein is phosphorylated on either amino acid serine-27 or serine-42. The protein is phosphorylated on amino acid serine-27 and/or serine-42. The protein may be phosphorylated on either of these amino acids, but our results do not tell us which it is. Under specific conditions, either one or the other or both amino acids may become phosphorylated.
  • 16. Qualified statements • Qualify statements only once • Aim for precision even in qualified statements The data may suggest that the molecular weight of the protein could be approximately 147kDa. The data indicate that the molecular weight of the protein is approximately 147kDa. The boiling point of the compound is approximately 67°C. The boiling point of the compound is in the range 65.5°C - 68°C.
  • 17. Response from the journal • Many excellent papers are rejected – this is not an affront to your dignity or intelligence. • Referees take a deal of time to review your paper – sometimes they get it wrong or fail to understand what you have written, but mostly their points are valid. • Wait 24 hours before firing off a reply to the journal. • Consult all of your fellow authors. • Do what is asked, if it is reasonable………….. • Make point by point responses when resubmitting.