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Opportunities for Medical Ceramics
Nano-655

NanoMarkets, LC
October 2013

www.nanomarkets.net

© 2013 NanoMarkets, LC
2

ABOUT NANOMARKETS
• NanoMarkets provides industry analysis of advanced materials
and their application in upstream markets
• Our work includes market, company and technology analysis,
market forecasting and due diligence
• Offerings include reports, custom consulting,
seminars/webinars and in-house training. NanoMarkets is
based in U.S., with extensive contacts all over the world

www.nanomarkets.net

© 2013 NanoMarkets, LC
2

ABOUT THE REPORT
In the past, medical ceramics were represented by ceramic and clay implants that
remained inert in the host and acted as scaffolds or supports. Today the scenario has
changed remarkably due to the introduction of an entirely new generation of bioceramics.
These implants are, amazingly, structurally and functionally compatible with living tissue in
the human body and contribute to the development of new tissue. Over the past two
decades, there has been tremendous improvement in the performance of these
bioceramics, and technology advances have created a very huge market for ceramics in
the medical sector.
Although there are a few risks and ambiguities regarding the use of implants and medical
devices based on ceramics, NanoMarkets certainly believes that the market for
implantable bioceramics will continue to grow in future. This growth can possibly be
converted into profitable businesses by the companies manufacturing the medical ceramic
devices and the firms that supply the necessary raw materials.

www.nanomarkets.net

© 2013 NanoMarkets, LC
2

RELATED REPORTS
Bio-Plastics Markets
Worldwide Medical Polymer Markets 2013-2020

www.nanomarkets.net

© 2013 NanoMarkets, LC
2

THE MEDICAL CERAMICS MARKET
• Advancements in medical ceramics has supported areas such
as medical device & implant and healthcare segments
• Arrival of related products such as piezo-ceramics and nanoceramics has further boosted these sectors
• Also creating opportunities for firms supplying raw materials
to these segments

www.nanomarkets.net

© 2013 NanoMarkets, LC
www.ecisolutions.com

OPPORTUNITIES IN MEDICAL DEVICES & IMPLANT SEGMENTS
PROSTHESES & BONE
REPLACEMENTS

All-ceramic
implants preferred
over ceramic-metal
and ceramicpolymer for small &
medium bone
replacements as
they offer

www.nanomarkets.net

• Better clinical trial
results
• Biocompatibility

• High degree of
osseo integration

© 2013 NanoMarkets, LC
ADVANCED PRODUCTION
METHODS

Injection molding, engineered coatings and
metal ceramic-assemblies have made complex
joints and small precision instruments a reality

Improved manufacturing processes will enhance
the application of medical ceramics to other
medical applications

Companies like Straumann, Nobel Biocare (NB),
and Zimmer adopting CAD/CAM for production
of implants

www.nanomarkets.net

© 2013 NanoMarkets, LC
BIOACTIVE CERAMIC
COATINGS

Combination mechanical & bioactive properties
makes ceramic coatings on metal useful for
medical applications

ACP, Glass ceramic coatings on titanium & DLC
coatings are a few examples.

Development in coating process technology,
making bioactive ceramic cost-effective

www.nanomarkets.net

© 2013 NanoMarkets, LC
PIEZO-CERAMICS & NANO-CERAMICS

Piezo-Ceramics in demand due to applicability in Piezoceramic sensors and motors in the medical diagnostic
equipments
• High-strength nano-composites and superior biocompatible
coatings for implants, a reality because of nanometer-sized
biomaterials
Nano-technology and micro-technology will continue to be
used in fabrication of bio-devices

• To be used for diagnosis and treatment of cancer because
of healing ability and their potential as a next generation
drug delivery system

www.nanomarkets.net

© 2013 NanoMarkets, LC
OPPORTUNITIES IN HEALTHCARE
ORTHOPEDICS & DENTISTRY

Bone scaffolding, a new technology in which medical ceramics
are finding potential
• Bio-ceramic hip joints are already a hit as these longer
lasting joints offer patients relatively active life.

Demand is likely to come from USA, as FDA has approved
ceramic-based implants
• Aging global population will heavily drive demand

www.nanomarkets.net

© 2013 NanoMarkets, LC
SCAFFOLD-GUIDED BONE
REGENERATION

Medical ceramicsare the perfect material for scaffold
guided bone regeneration

• Wound healing is another application area in which
many companies are active
In addition to knee and hip replacements, small bone
replacements are likely to see growth

• A number of regenerative solutions now being offered
by companies like Zimmer

www.nanomarkets.net

© 2013 NanoMarkets, LC
INJECT ABLE CERAMIC &
REGENERATION

Immediate pain relief, durability, full weight-bearing recovery,
bone consolidation, and maintenance of the structural
integrity of the bone favors injectable ceramics for
reconstructive foot and back-filling procedures
• Bonesupport, curasan (DE) and covalent Materials
Corporation (JP) are active in this area
Injectable ceramics that can be injected with minimal invasion
has potential to enter bone reconstruction, drug delivery
system and other medical applications
• Such bone substitute solutions have trong business
potential and firms that have recognized this will benefit in
future

www.nanomarkets.net

© 2013 NanoMarkets, LC
OPPORTUNITIES FOR MATERIAL FIRMS
KEYS TO SUCCESS

Time
Reduction

• Through adoption of innovative
manufacturing processes

Attaining
scalability

• In a cost-effective manner, without
impacting biocompatibility

Reliable
Process

www.nanomarkets.net

• Adoption for manufacturing of
large bone replacement implants
to reduce pricing disparity

© 2013 NanoMarkets, LC
FACTORS AFFECTING
MANUFACTURERS

Clinical Trials:Result will have an
influence on the
demand for medical
ceramics

Environmental
Regulations:By overcoming such
regulations firms can
get advantage

Trade Barriers:Both tariff & non-tariff
barriers likely to impact
this industry negatively

Globalization:Either lead to
innovative products or
may allow penetration
of low quality products

R & D needs:Significant amount of
R & D needed in order
to be innovative in this
industry

www.nanomarkets.net

© 2013 NanoMarkets, LC
KEY FIRMS IN MEDICAL CERAMICS INDUSTRY
Orthopedic Implant Manufacturers
Company
DePuy(US)

Description
Innovative product line up
Regularly launching new products

Zimmer Holdings (US)

Strong distribution network
Adopts acquisition strategy for growth

Stryker Corp. (US)

Dominance in the orthopedic segment particularly in
cranio-maxillofacial market
Strong presence in Asian market
Acquisition strategy for growth
Strong product portfolio

Biomet 3I (US)
Well established in hip implant segment
Synthes (US)

www.nanomarkets.net

Leadership in cranio-maxillofacial market particularly in
Japan

© 2013 NanoMarkets, LC
Dental Implant Manufacturers
Company

Description
Soft tissue level implant is considered a benchmark in
commercial and clinical applications.

Straumann (Switzerland)

A large portfolio of dental products
CAD/CAM based solutions
Unique tip and thread design of its Nobel Active implants

Nobel Biocare
(Switzerland)

Dental products based on wide variety of materials, such
as acrylics, alumina, zirconia, titanium, and cobalt
chromium.
CAD/CAM based solutions

Zimmer (US)

Well established in dental space & strong product
portfolio
CAD/CAM based high precision manufacturing technique
Comprehensive range of dental implants

Biomet 3I (US)

www.nanomarkets.net

Pioneered the development of biological driven implants

© 2013 NanoMarkets, LC
Materials & Injectable Ceramics Suppliers
Company

Description
At the forefront of several ceramic innovations

Morgan Technical
Ceramics (UK)
CeramTec(DE)
Kyocera (JP)

Ability to customize product
Strong presence in medical equipment segment
Specializes in small ceramic components for implanted
electronic medical devices
CAD/CAM-based dental restoration solution

3M (US)
Reliable aesthetics, strength of products for dental
applications
CoorsTek (US)
Bonesupport (Sweden)

www.nanomarkets.net

Strong presence in labware, precision instruments, and
pump components
Patented CERAMENT technology, that helps to
remodel bone using their osteoconductive property

© 2013 NanoMarkets, LC
SUMMARY: MARKET PREDICTION FOR 2013-2020

Global Medical Ceramics Market
© NanoMarkets 2013

Ceramic market is
likely to more than
double in terms of
revenue

3,500
3,000

Growing at a
CAGR of 15.54%
through the
forecasting
period

To reach $ 3
billion in
revenues by
2020

US$ Millions

2,500
2,000
1,500
1,000
500
0
2013

www.nanomarkets.net

2014

2015

2016

2017

2018

2019

2020

© 2013 NanoMarkets, LC
LEADING MATERIAL SEGMENTS
Leading Material Segments
3,000

2,500

Alumina to
dominate
the materials
segment
US$ Millions

2,000

Bioglass to
grow faster
than other
segments

Zirconia to
be the
second most
used
material

1,500

1,000

500

0
2013
Alumina

2014

2015
Zirconia

2016

2017

2018

Hydroxyapatite

2019

2020

Bioglass
3

CONTACT US
Address:
NanoMarkets, LC
PO Box 3840
Glen Allen, VA 23058
Telephone / Fax
804-270-1718
804-360-7259

facebook.com/pages/NanoMarkets/
twitter.com/nanomarkets

Email / Web
info@nanomarkets.net
www.nanomarkets.net

linkedin.com/in/nanomarkets
nanomarkets.net/rssfeeds

www.nanomarkets.net

© 2013 NanoMarkets, LC

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PowerPoint Slides from NanoMarkets Report on Medical Ceramics

  • 1. www.ecisolutions.com Opportunities for Medical Ceramics Nano-655 NanoMarkets, LC October 2013 www.nanomarkets.net © 2013 NanoMarkets, LC
  • 2. 2 ABOUT NANOMARKETS • NanoMarkets provides industry analysis of advanced materials and their application in upstream markets • Our work includes market, company and technology analysis, market forecasting and due diligence • Offerings include reports, custom consulting, seminars/webinars and in-house training. NanoMarkets is based in U.S., with extensive contacts all over the world www.nanomarkets.net © 2013 NanoMarkets, LC
  • 3. 2 ABOUT THE REPORT In the past, medical ceramics were represented by ceramic and clay implants that remained inert in the host and acted as scaffolds or supports. Today the scenario has changed remarkably due to the introduction of an entirely new generation of bioceramics. These implants are, amazingly, structurally and functionally compatible with living tissue in the human body and contribute to the development of new tissue. Over the past two decades, there has been tremendous improvement in the performance of these bioceramics, and technology advances have created a very huge market for ceramics in the medical sector. Although there are a few risks and ambiguities regarding the use of implants and medical devices based on ceramics, NanoMarkets certainly believes that the market for implantable bioceramics will continue to grow in future. This growth can possibly be converted into profitable businesses by the companies manufacturing the medical ceramic devices and the firms that supply the necessary raw materials. www.nanomarkets.net © 2013 NanoMarkets, LC
  • 4. 2 RELATED REPORTS Bio-Plastics Markets Worldwide Medical Polymer Markets 2013-2020 www.nanomarkets.net © 2013 NanoMarkets, LC
  • 5. 2 THE MEDICAL CERAMICS MARKET • Advancements in medical ceramics has supported areas such as medical device & implant and healthcare segments • Arrival of related products such as piezo-ceramics and nanoceramics has further boosted these sectors • Also creating opportunities for firms supplying raw materials to these segments www.nanomarkets.net © 2013 NanoMarkets, LC
  • 6. www.ecisolutions.com OPPORTUNITIES IN MEDICAL DEVICES & IMPLANT SEGMENTS PROSTHESES & BONE REPLACEMENTS All-ceramic implants preferred over ceramic-metal and ceramicpolymer for small & medium bone replacements as they offer www.nanomarkets.net • Better clinical trial results • Biocompatibility • High degree of osseo integration © 2013 NanoMarkets, LC
  • 7. ADVANCED PRODUCTION METHODS Injection molding, engineered coatings and metal ceramic-assemblies have made complex joints and small precision instruments a reality Improved manufacturing processes will enhance the application of medical ceramics to other medical applications Companies like Straumann, Nobel Biocare (NB), and Zimmer adopting CAD/CAM for production of implants www.nanomarkets.net © 2013 NanoMarkets, LC
  • 8. BIOACTIVE CERAMIC COATINGS Combination mechanical & bioactive properties makes ceramic coatings on metal useful for medical applications ACP, Glass ceramic coatings on titanium & DLC coatings are a few examples. Development in coating process technology, making bioactive ceramic cost-effective www.nanomarkets.net © 2013 NanoMarkets, LC
  • 9. PIEZO-CERAMICS & NANO-CERAMICS Piezo-Ceramics in demand due to applicability in Piezoceramic sensors and motors in the medical diagnostic equipments • High-strength nano-composites and superior biocompatible coatings for implants, a reality because of nanometer-sized biomaterials Nano-technology and micro-technology will continue to be used in fabrication of bio-devices • To be used for diagnosis and treatment of cancer because of healing ability and their potential as a next generation drug delivery system www.nanomarkets.net © 2013 NanoMarkets, LC
  • 10. OPPORTUNITIES IN HEALTHCARE ORTHOPEDICS & DENTISTRY Bone scaffolding, a new technology in which medical ceramics are finding potential • Bio-ceramic hip joints are already a hit as these longer lasting joints offer patients relatively active life. Demand is likely to come from USA, as FDA has approved ceramic-based implants • Aging global population will heavily drive demand www.nanomarkets.net © 2013 NanoMarkets, LC
  • 11. SCAFFOLD-GUIDED BONE REGENERATION Medical ceramicsare the perfect material for scaffold guided bone regeneration • Wound healing is another application area in which many companies are active In addition to knee and hip replacements, small bone replacements are likely to see growth • A number of regenerative solutions now being offered by companies like Zimmer www.nanomarkets.net © 2013 NanoMarkets, LC
  • 12. INJECT ABLE CERAMIC & REGENERATION Immediate pain relief, durability, full weight-bearing recovery, bone consolidation, and maintenance of the structural integrity of the bone favors injectable ceramics for reconstructive foot and back-filling procedures • Bonesupport, curasan (DE) and covalent Materials Corporation (JP) are active in this area Injectable ceramics that can be injected with minimal invasion has potential to enter bone reconstruction, drug delivery system and other medical applications • Such bone substitute solutions have trong business potential and firms that have recognized this will benefit in future www.nanomarkets.net © 2013 NanoMarkets, LC
  • 13. OPPORTUNITIES FOR MATERIAL FIRMS KEYS TO SUCCESS Time Reduction • Through adoption of innovative manufacturing processes Attaining scalability • In a cost-effective manner, without impacting biocompatibility Reliable Process www.nanomarkets.net • Adoption for manufacturing of large bone replacement implants to reduce pricing disparity © 2013 NanoMarkets, LC
  • 14. FACTORS AFFECTING MANUFACTURERS Clinical Trials:Result will have an influence on the demand for medical ceramics Environmental Regulations:By overcoming such regulations firms can get advantage Trade Barriers:Both tariff & non-tariff barriers likely to impact this industry negatively Globalization:Either lead to innovative products or may allow penetration of low quality products R & D needs:Significant amount of R & D needed in order to be innovative in this industry www.nanomarkets.net © 2013 NanoMarkets, LC
  • 15. KEY FIRMS IN MEDICAL CERAMICS INDUSTRY Orthopedic Implant Manufacturers Company DePuy(US) Description Innovative product line up Regularly launching new products Zimmer Holdings (US) Strong distribution network Adopts acquisition strategy for growth Stryker Corp. (US) Dominance in the orthopedic segment particularly in cranio-maxillofacial market Strong presence in Asian market Acquisition strategy for growth Strong product portfolio Biomet 3I (US) Well established in hip implant segment Synthes (US) www.nanomarkets.net Leadership in cranio-maxillofacial market particularly in Japan © 2013 NanoMarkets, LC
  • 16. Dental Implant Manufacturers Company Description Soft tissue level implant is considered a benchmark in commercial and clinical applications. Straumann (Switzerland) A large portfolio of dental products CAD/CAM based solutions Unique tip and thread design of its Nobel Active implants Nobel Biocare (Switzerland) Dental products based on wide variety of materials, such as acrylics, alumina, zirconia, titanium, and cobalt chromium. CAD/CAM based solutions Zimmer (US) Well established in dental space & strong product portfolio CAD/CAM based high precision manufacturing technique Comprehensive range of dental implants Biomet 3I (US) www.nanomarkets.net Pioneered the development of biological driven implants © 2013 NanoMarkets, LC
  • 17. Materials & Injectable Ceramics Suppliers Company Description At the forefront of several ceramic innovations Morgan Technical Ceramics (UK) CeramTec(DE) Kyocera (JP) Ability to customize product Strong presence in medical equipment segment Specializes in small ceramic components for implanted electronic medical devices CAD/CAM-based dental restoration solution 3M (US) Reliable aesthetics, strength of products for dental applications CoorsTek (US) Bonesupport (Sweden) www.nanomarkets.net Strong presence in labware, precision instruments, and pump components Patented CERAMENT technology, that helps to remodel bone using their osteoconductive property © 2013 NanoMarkets, LC
  • 18. SUMMARY: MARKET PREDICTION FOR 2013-2020 Global Medical Ceramics Market © NanoMarkets 2013 Ceramic market is likely to more than double in terms of revenue 3,500 3,000 Growing at a CAGR of 15.54% through the forecasting period To reach $ 3 billion in revenues by 2020 US$ Millions 2,500 2,000 1,500 1,000 500 0 2013 www.nanomarkets.net 2014 2015 2016 2017 2018 2019 2020 © 2013 NanoMarkets, LC
  • 19. LEADING MATERIAL SEGMENTS Leading Material Segments 3,000 2,500 Alumina to dominate the materials segment US$ Millions 2,000 Bioglass to grow faster than other segments Zirconia to be the second most used material 1,500 1,000 500 0 2013 Alumina 2014 2015 Zirconia 2016 2017 2018 Hydroxyapatite 2019 2020 Bioglass
  • 20. 3 CONTACT US Address: NanoMarkets, LC PO Box 3840 Glen Allen, VA 23058 Telephone / Fax 804-270-1718 804-360-7259 facebook.com/pages/NanoMarkets/ twitter.com/nanomarkets Email / Web info@nanomarkets.net www.nanomarkets.net linkedin.com/in/nanomarkets nanomarkets.net/rssfeeds www.nanomarkets.net © 2013 NanoMarkets, LC