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An Introduction to the Human Body
• Anatomy
  – science of structure
  – relationships revealed by dissection (cutting apart)
  – imaging techniques
• Physiology
  – science of body functions
  – normal adult physiology is studied in this class
  – some genetic variations occur
ANATOMY AND PHYSIOLOGY
           DEFINED

• Anatomy
  – the study of structure and the relationships
    among structures.
• Subdivisions
  – surface anatomy, gross anatomy, systemic
    anatomy, regional anatomy, radiographic
    anatomy, developmental anatomy, embryology,
    cytology, and pathological anatomy
ANATOMY AND PHYSIOLOGY
           DEFINED

• Physiology
  – the study of how body structures function
• Subdivisions of physiology include
  – cell physiology, systems physiology,
    pathophysiology, exercise physiology,
    neurophysiology, endocrinology,
    cardiovascular physiology, immunophysiology,
     respiratory physiology, renal physiology, and
    reproductive physiology
Structural Organization of Matter
1. Chemical Level
   a. Atoms
   (Proton, Neutron, electrons)
   b. Molecules
   (Two or more atoms joined
   together by either covalent or
   ionic bonds)
   Four biologically important
   organic molecules in the
   human body
   a. Proteins which are made
       from 20 different Amino
   Acids
Structural Organization of Matter
   Four Biologically-Important
   Organic molecules:
   b. Complex Carbohydrates
      made from simple sugars
   c. Nucleic Acids made for
   nucleotides
   d. Lipids made from fatty
   acids and glycerol

2. Cells
   (Smallest structural and
   functional units of the human
   body)
Structural Organization of Matter
1. Tissues
   (group of cells and the
   materials surrounding them
   that work together to
   perform a particular
   function)
3. Organs
   (composed of two or more
   tissues work together to
   provide specific functions and
   they usually have specific
   shapes)
Structural Organization of Matter
1. Organ systems
   (consist of one or more
   organs that provide a
   common function) Examples
   covered in Anatomy &
   Physiology 242:
   a. Integumentary system
   b. Skeletal system
   c. Muscular system
   d. Nervous system
Structural Organization of Matter
Anatomy & Physiology 243:
e. Endocrine system
f. Cardiovascular system
g. Lymphatic system
h. Respiratory system
I. Digestive system
j. Urinary system
k. Reproductive system
Basic Life Processes

1. Metabolism
   Sum of all biochemical
   processes of cells, tissues,
   organs, and organ systems
3. Responsiveness
   Ability to detect and respond to
   changes in the internal and
   external environment
5. Movement
   Occurs at the intracellular,
   cellular, organ levels
Basic Life Processes

1. Growth
    Increase in number of cells, size of cells,
    tissues, organs, and the body. Single cell
    to multicellular complex organism
3. Differentiation
    Process a cell undergoes to develop from a
    unspecialized to a specialized cell
5. Reproduction
   Formation of new cells for growth,
    repair, or replacement, or the production
    of a new individual.
Basic Life Processes

• Homeostasis
  Equilibrium of the body’s internal
  environment produced by the
  interaction of organ systems and
  regulatory processes (feedback
  systems).
  Homeostasis is a dynamic condition in
  response to changing conditions.
  The two body systems that largely
  control the body’s homeostatic state:
       1. Nervous system
       2. Endocrine system
Control of Homeostasis

• Homeostasis is continually being disrupted by
   – external stimuli
       • intense heat, cold , and lack of oxygen
   – internal stimuli
       • psychological stresses
       • exercise
• Disruptions are usually mild & temporary
• If homeostasis is not maintained, death may result
CONTROL OF HOMEOSTASIS

• Homeostatic imbalances occur because of disruptions
  from the external or internal environments.
   – Homeostasis is regulated by the nervous system and
     endocrine system, acting together or independently.
   – The nervous system detects changes and sends nerve
     impulses to counteract the disruption.
   – The endocrine system regulates homeostasis by
     secreting hormones.
• Whereas nerve impulses cause rapid changes, hormones
  usually work more slowly.
• Examples: CO2, O2, temperature, pH, blood pressure, …
Example of Homeostasis
         Fluid balance in the Body

•  Compartments
   for Body Fluids
2. Intracellular
3. Extracellular
   a. Interstitial
   b. Plasma
Components of Feedback Loop

       • Receptor
          – monitors a controlled condition
       • Control center
          – determines next action
       • Effector
          – receives directions from the control
            center
          – produces a response that changes the
            controlled condition
Basic Components
  of a Negative
Feedback System
Basic Components of
a Positive Feedback
      System
Homeostatic Imbalances

• Disruption of homeostasis can lead to disease and death.

• Disorder is a general term for any change or abnormality
  of function.
• Disease is a more specific term for an illness characterized
  by a recognizable set of signs and symptoms.
   – A local disease is one that affects one part or a limited
      region of the body.
   – A systemic disease affects either the entire body or
      several parts.
Homeostatic Imbalances

• Disease is a more specific term for an illness characterized
  by a recognizable set of signs and symptoms.
   – Signs are objective changes that a clinician can observe
      and measure; e.g., fever or rash.
   – Symptoms are subjective changes in body functions
      that are not apparent to an observer; e.g., headache or
      nausea.
• Diagnosis is the art of distinguishing one disease from
  another or determining the nature of a disease; a diagnosis
  is generally arrived at after the taking of a medical history
  and the administration of a physical examination.
Anatomical Position

• The anatomical position is a standardized
  method of observing or imaging the body
  that allows precise and consistent
  anatomical references.
• When in the anatomical position, the subject
  stands (Figure 1.5).
   – standing upright
   – facing the observer, head level
   – eyes facing forward
   – feet flat on the floor
   – arms at the sides
   – palms turned forward (ventral)
Basic
Anatomical
Terminology
Basic
Anatomical
Terminology
Reclining Position

• If the body is lying face down, it is in the prone position.

• If the body is lying face up, it is in the supine position.
Basic body
    planes or
     sections

These terms are used
for planes or sections
that cut the body,
organs, tissues, or cells
Example of how planes
 would cut the brain
Two
 Principal
   Body
Cavities and
   their
Subdivisions
Directional Terms Used to Describe the
  Position of one Structure to Another
Superior/Inferior
(Cephalic/Caudal)
Anterior/Posterior
(Ventral/Dorsal)
Medial/Lateral
Intermediate: Between
Ipsilateral/Contralateral
Proximal/Distal
Superficial/Deep
Methods of dividing the
Abdominopelvic cavity

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Anatomy terminology

  • 1. An Introduction to the Human Body • Anatomy – science of structure – relationships revealed by dissection (cutting apart) – imaging techniques • Physiology – science of body functions – normal adult physiology is studied in this class – some genetic variations occur
  • 2. ANATOMY AND PHYSIOLOGY DEFINED • Anatomy – the study of structure and the relationships among structures. • Subdivisions – surface anatomy, gross anatomy, systemic anatomy, regional anatomy, radiographic anatomy, developmental anatomy, embryology, cytology, and pathological anatomy
  • 3. ANATOMY AND PHYSIOLOGY DEFINED • Physiology – the study of how body structures function • Subdivisions of physiology include – cell physiology, systems physiology, pathophysiology, exercise physiology, neurophysiology, endocrinology, cardiovascular physiology, immunophysiology, respiratory physiology, renal physiology, and reproductive physiology
  • 4. Structural Organization of Matter 1. Chemical Level a. Atoms (Proton, Neutron, electrons) b. Molecules (Two or more atoms joined together by either covalent or ionic bonds) Four biologically important organic molecules in the human body a. Proteins which are made from 20 different Amino Acids
  • 5. Structural Organization of Matter Four Biologically-Important Organic molecules: b. Complex Carbohydrates made from simple sugars c. Nucleic Acids made for nucleotides d. Lipids made from fatty acids and glycerol 2. Cells (Smallest structural and functional units of the human body)
  • 6. Structural Organization of Matter 1. Tissues (group of cells and the materials surrounding them that work together to perform a particular function) 3. Organs (composed of two or more tissues work together to provide specific functions and they usually have specific shapes)
  • 7. Structural Organization of Matter 1. Organ systems (consist of one or more organs that provide a common function) Examples covered in Anatomy & Physiology 242: a. Integumentary system b. Skeletal system c. Muscular system d. Nervous system
  • 8. Structural Organization of Matter Anatomy & Physiology 243: e. Endocrine system f. Cardiovascular system g. Lymphatic system h. Respiratory system I. Digestive system j. Urinary system k. Reproductive system
  • 9. Basic Life Processes 1. Metabolism Sum of all biochemical processes of cells, tissues, organs, and organ systems 3. Responsiveness Ability to detect and respond to changes in the internal and external environment 5. Movement Occurs at the intracellular, cellular, organ levels
  • 10. Basic Life Processes 1. Growth Increase in number of cells, size of cells, tissues, organs, and the body. Single cell to multicellular complex organism 3. Differentiation Process a cell undergoes to develop from a unspecialized to a specialized cell 5. Reproduction Formation of new cells for growth, repair, or replacement, or the production of a new individual.
  • 11. Basic Life Processes • Homeostasis Equilibrium of the body’s internal environment produced by the interaction of organ systems and regulatory processes (feedback systems). Homeostasis is a dynamic condition in response to changing conditions. The two body systems that largely control the body’s homeostatic state: 1. Nervous system 2. Endocrine system
  • 12. Control of Homeostasis • Homeostasis is continually being disrupted by – external stimuli • intense heat, cold , and lack of oxygen – internal stimuli • psychological stresses • exercise • Disruptions are usually mild & temporary • If homeostasis is not maintained, death may result
  • 13. CONTROL OF HOMEOSTASIS • Homeostatic imbalances occur because of disruptions from the external or internal environments. – Homeostasis is regulated by the nervous system and endocrine system, acting together or independently. – The nervous system detects changes and sends nerve impulses to counteract the disruption. – The endocrine system regulates homeostasis by secreting hormones. • Whereas nerve impulses cause rapid changes, hormones usually work more slowly. • Examples: CO2, O2, temperature, pH, blood pressure, …
  • 14. Example of Homeostasis Fluid balance in the Body • Compartments for Body Fluids 2. Intracellular 3. Extracellular a. Interstitial b. Plasma
  • 15. Components of Feedback Loop • Receptor – monitors a controlled condition • Control center – determines next action • Effector – receives directions from the control center – produces a response that changes the controlled condition
  • 16. Basic Components of a Negative Feedback System
  • 17. Basic Components of a Positive Feedback System
  • 18. Homeostatic Imbalances • Disruption of homeostasis can lead to disease and death. • Disorder is a general term for any change or abnormality of function. • Disease is a more specific term for an illness characterized by a recognizable set of signs and symptoms. – A local disease is one that affects one part or a limited region of the body. – A systemic disease affects either the entire body or several parts.
  • 19. Homeostatic Imbalances • Disease is a more specific term for an illness characterized by a recognizable set of signs and symptoms. – Signs are objective changes that a clinician can observe and measure; e.g., fever or rash. – Symptoms are subjective changes in body functions that are not apparent to an observer; e.g., headache or nausea. • Diagnosis is the art of distinguishing one disease from another or determining the nature of a disease; a diagnosis is generally arrived at after the taking of a medical history and the administration of a physical examination.
  • 20. Anatomical Position • The anatomical position is a standardized method of observing or imaging the body that allows precise and consistent anatomical references. • When in the anatomical position, the subject stands (Figure 1.5). – standing upright – facing the observer, head level – eyes facing forward – feet flat on the floor – arms at the sides – palms turned forward (ventral)
  • 23. Reclining Position • If the body is lying face down, it is in the prone position. • If the body is lying face up, it is in the supine position.
  • 24. Basic body planes or sections These terms are used for planes or sections that cut the body, organs, tissues, or cells
  • 25. Example of how planes would cut the brain
  • 26. Two Principal Body Cavities and their Subdivisions
  • 27. Directional Terms Used to Describe the Position of one Structure to Another Superior/Inferior (Cephalic/Caudal) Anterior/Posterior (Ventral/Dorsal) Medial/Lateral Intermediate: Between Ipsilateral/Contralateral Proximal/Distal Superficial/Deep
  • 28. Methods of dividing the Abdominopelvic cavity