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Michel Sainville
Marketing Division
Background informations
Advances
in endoscopic
technology
Longer
procedures,
deeper sedation
Higher ARF risk
ARF Statistics
Every day, in each european country, the 0,01% of
the population undergoes an UE.
The 5% of those patients develops an ARF.
(P/10k)(0.07 ± ε)Time
Europe= (731mln/10k)(0.07 ± 0.02)1
3˙655 to 6˙579 ARF per day.
Italy= (61mln/10k)(0.07 ± 0.02)1
305 to 549 ARF per day
Physician’s dilemma
Treating ARF
Non invasive
ventilation
Planned
Prediction
errors
Unexpected
Procedure
interruption
Intubation
Risks
Costs
Immediate and unplanned intra-procedural ventilation
Physician’s dilemma
Treating ARF
Non invasive
ventilation
Planned
Prediction
errors
Unexpected
Procedure
interruption
immediate
ventilation
Intubation
Risks
Costs
Applications
• Tracheal intubation
Emergency
department
• FOB: fiberoptic bronchoscopy
• Gastroscopy
• Enteroscopy
• TEE: trans-esophageal echocardiography
• EBUS: endobronchial ultrasound
• ERCP: Endoscopic retrograde
cholangiopancreatography
Endoscopic
procedures
MARKET SIZE
Assumptions
• Fewest ARF scenario
• Even treatment proportions
• Intra-procedural ventilation only (- NIV, CPAP)
EU market size
219˙300 units per year
Italian estimated market size
18˙300 units per year
Thank You

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Unplanned intra-procedural NIV