The document summarizes key points about human biology and oncology: 1. It defines cancer terminology and distinguishes between characteristics of benign and malignant tumors. 2. It lists the main categories of cancer etiology as environmental factors, viruses, and lifestyle factors like smoking, diet, alcohol, medical drugs and hormones, and heredity. 3. It provides cancer statistics for 2000, noting the most common cancer types and that rates have declined since 1989, in part due to decreased tobacco use.

1. Human Biology III Oncology I Ken Bauer [email_address]

10. Leading Sites of New Cancer Cases and Deaths—2000 Estimates

11. Age-Adjusted Cancer Death Rates,* Females by Site, US, 1930-1996

12. Age-Adjusted Cancer Death Rates,* Males by Site, US, 1930-1996

26. Cell Cycle Entry to Death: Regulation Growth Factor Receptor Activation Intracellular Kinase Cascade Early Nuclear Proteins (myc, fos, jun etc.) Cell Cycle Activators (cyclins) Regulators (Rb) Genome Checkers (p53) Apoptosis: Cell Cycle Balancers (bcl-2 family)

28. Questions?