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H1N1 "Swine Flu" Vaccine Market Review (Revenues, Forecasts, Lessons for
Future Pandemic Vaccines)

May 1, 2010

The H1N1 flu epidemic created a public health emergency in 2009. It also created an
opportunity for vaccine manufacturers to demonstrate that working with governments of
the US and countries around the world, they could manufacture and distribute a vaccine
for the virus strain that may have had an impact in reducing cases and deaths.

Who were the companies that performed best in this market? How did goverment
contracts play out? Most importantly, what are lessons for future pandemic and high
publicity vaccine products? Kalorama has looked at vaccine products over the past
decade and has seen the rise of interest in these products among pharmaceutical
companies. While many suggest the H1N1 was a one time event, Kalorama believes
there is something important to be gained in a market review of 2009 flu vaccine sales
that will inform executives, investors and market watchers who are interested in the
vaccine market.

This Kalorama Information report takes a detailed look at the H1N1 vaccine sales of
2009 based on available annual reports. Companies covered include AstraZeneca,
Novartis, Glaxo and CSL among others. As part of its coverage, the report includes:

      2009 H1N1 Vaccine Sales Results
      Stockpiles, Returns, Delivery Systems and other Issues and Trends in Vaccine
      Sales
      H1N1 Etiology and Statistics
      Forecasts for 2010-2013 Influenza Vaccine Market
      Trending in Government Contracts
      Seasonal and H1N1 Flu Market Interplay
      Conclusions for Future Pandemic Vaccine Sales
      Market Share of Major Companies
      Company Profiles

As part of its coverage, the following vaccine makers are profiled

      Baxter Healthcare
GlaxoSmithKline
      CSL
      Medimmune (Astra Zeneca)
      Merck & Co. Inc
      Novartis
      Sanofi Pasteur
      Sinovac
      Hualan Biological Engineering Co.
      Novovax

This Kalorama Information report was created as the result of both secondary and
primary research. Research was conducted into the annual reports of major vaccine
concerns, trade media coverage, company websites and medical and government
literature. Interviews were used to make forecasts on the vaccine market and the
influenza vaccine market for 2010-2014, which have been utilized in our estimate of the
swine flu vaccine market impact for the 2010-2014 years. Historical information for this
report was gathered from a wide variety of published sources including company reports
and filings, government documents, legal filings, trade journals, newspapers and
business press, analysts’ reports and other sources.



Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

      Vaccine Products
      Sales Results
      Forecasts
      Scope and Methodology

CHAPTER TWO: INTRODUCTION

      Vaccination For Swine Flu
      Trends Driving Vaccines
      H1N1 added to new Immunization Schedules
      Swine Flu Vaccine Manufacturing Process
      Novartis
      CSL
      Baxter Vaccines

CHAPTER THREE: MARKET TRENDS IMPACTING SWINE FLU VACCINE

      H1n1 Vaccine Returns and Redirects
      Vaccination Resistance
      DTC Advertising And Retail Clinics
H1n1 Statiscs Compared to Seasonal Flu
    Other Vaccine Revenue Earners (Stores, Doctors, Insurance Companies)
    Showcase for Intranasal Delivery
    Vaccine Supply Issues
    Next Pandemic’ Strategy

CHAPTER FOUR: MARKET ANALYSIS

    Products on the Market
    Key Drivers
    Analysis of 2009 Sales Results
    Analysis of 2009 Sales Results
    Market By Region
    Market By Delivery System
    Conclusions
    Market Forecasts
       o Gardasil as a Model
       o Gardasil/Cervarix Sales, 2006-2010(E)
       o Quadravalent Vaccine
       o H1N1 & Influenza Vaccine Market Forecast

CHAPTER FIVE: COMPANY PROFILES

    Baxter Healthcare
    GlaxoSmithKline
    CSL
    Medimmune (Astra Zeneca)
    Merck & Co. Inc
    Novartis
    Sanofi Pasteur
    Sinovac
    Hualan Biological Engineering Co.
    Novovax.

                             TABLE OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

    Table 1-1: US& Worldwide A/H1N1 Cases
    Table 1-2: H1N1 Vaccine Products on the Market
    Table 1-3: Swine Flu Vaccine Sales, 2009

CHAPTER TWO: INTRODUCTION

    Table 2-2: Previous Flu Outbreaks
    Table 2-2: WHO GAR Update on Swine Flu March 2010
Table 2-3: US& Worldwide A/H1N1 Cases
       Table 2-4: Deaths from A/H1N1
       Figure 2-1: Sales Growth of Vaccines vs. Pharmaceuticals 2004-2013

CHAPTER FOUR: MARKET ANALYSIS

       Table 4-1: Selected Government Orders for Swine Flu Vaccine
       Figure 4-1: Doses Ordered as a Percentage of Population, Select Countries
       (United States, UK, Netherlands, Brazil, Croatia, France)
       Table 4-2: Swine Flu Vaccine Sales, 2009
       Figure 4-2: Estimated Regional Swine Flu Sales, 2009 (NA, EU, ASIA, ROW)
       Figure 4-3: Delivery System Used (Injectible, Intranasal)
       Table 4-4: World Cervical CancerVaccine Market (Gardasil and Cervarix) 2004-
       2010
       Table 4-5: Market Forecast: H1N1 Vaccine sales
       Table 4-6: Market Forecast: Influenza Vaccine with H1N1 impact
       Figure 4-5: Market Forecast: Influenza Vaccine with H1N1 Impact



Available immediately for Online Download at
http://www.marketresearch.com/product/display.asp?productid=2651343




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UK +44.207.256.3920

Int'l: +1.240.747.3093

Fax: 240.747.3004

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H1N1 "Swine Flu" Vaccine Market Review (Revenues, Forecasts, Lessons for Future Pandemic Vaccines)

  • 1. Get more info on this report! H1N1 "Swine Flu" Vaccine Market Review (Revenues, Forecasts, Lessons for Future Pandemic Vaccines) May 1, 2010 The H1N1 flu epidemic created a public health emergency in 2009. It also created an opportunity for vaccine manufacturers to demonstrate that working with governments of the US and countries around the world, they could manufacture and distribute a vaccine for the virus strain that may have had an impact in reducing cases and deaths. Who were the companies that performed best in this market? How did goverment contracts play out? Most importantly, what are lessons for future pandemic and high publicity vaccine products? Kalorama has looked at vaccine products over the past decade and has seen the rise of interest in these products among pharmaceutical companies. While many suggest the H1N1 was a one time event, Kalorama believes there is something important to be gained in a market review of 2009 flu vaccine sales that will inform executives, investors and market watchers who are interested in the vaccine market. This Kalorama Information report takes a detailed look at the H1N1 vaccine sales of 2009 based on available annual reports. Companies covered include AstraZeneca, Novartis, Glaxo and CSL among others. As part of its coverage, the report includes: 2009 H1N1 Vaccine Sales Results Stockpiles, Returns, Delivery Systems and other Issues and Trends in Vaccine Sales H1N1 Etiology and Statistics Forecasts for 2010-2013 Influenza Vaccine Market Trending in Government Contracts Seasonal and H1N1 Flu Market Interplay Conclusions for Future Pandemic Vaccine Sales Market Share of Major Companies Company Profiles As part of its coverage, the following vaccine makers are profiled Baxter Healthcare
  • 2. GlaxoSmithKline CSL Medimmune (Astra Zeneca) Merck & Co. Inc Novartis Sanofi Pasteur Sinovac Hualan Biological Engineering Co. Novovax This Kalorama Information report was created as the result of both secondary and primary research. Research was conducted into the annual reports of major vaccine concerns, trade media coverage, company websites and medical and government literature. Interviews were used to make forecasts on the vaccine market and the influenza vaccine market for 2010-2014, which have been utilized in our estimate of the swine flu vaccine market impact for the 2010-2014 years. Historical information for this report was gathered from a wide variety of published sources including company reports and filings, government documents, legal filings, trade journals, newspapers and business press, analysts’ reports and other sources. Table of Contents CHAPTER ONE: EXECUTIVE SUMMARY Vaccine Products Sales Results Forecasts Scope and Methodology CHAPTER TWO: INTRODUCTION Vaccination For Swine Flu Trends Driving Vaccines H1N1 added to new Immunization Schedules Swine Flu Vaccine Manufacturing Process Novartis CSL Baxter Vaccines CHAPTER THREE: MARKET TRENDS IMPACTING SWINE FLU VACCINE H1n1 Vaccine Returns and Redirects Vaccination Resistance DTC Advertising And Retail Clinics
  • 3. H1n1 Statiscs Compared to Seasonal Flu Other Vaccine Revenue Earners (Stores, Doctors, Insurance Companies) Showcase for Intranasal Delivery Vaccine Supply Issues Next Pandemic’ Strategy CHAPTER FOUR: MARKET ANALYSIS Products on the Market Key Drivers Analysis of 2009 Sales Results Analysis of 2009 Sales Results Market By Region Market By Delivery System Conclusions Market Forecasts o Gardasil as a Model o Gardasil/Cervarix Sales, 2006-2010(E) o Quadravalent Vaccine o H1N1 & Influenza Vaccine Market Forecast CHAPTER FIVE: COMPANY PROFILES Baxter Healthcare GlaxoSmithKline CSL Medimmune (Astra Zeneca) Merck & Co. Inc Novartis Sanofi Pasteur Sinovac Hualan Biological Engineering Co. Novovax. TABLE OF EXHIBITS CHAPTER ONE: EXECUTIVE SUMMARY Table 1-1: US& Worldwide A/H1N1 Cases Table 1-2: H1N1 Vaccine Products on the Market Table 1-3: Swine Flu Vaccine Sales, 2009 CHAPTER TWO: INTRODUCTION Table 2-2: Previous Flu Outbreaks Table 2-2: WHO GAR Update on Swine Flu March 2010
  • 4. Table 2-3: US& Worldwide A/H1N1 Cases Table 2-4: Deaths from A/H1N1 Figure 2-1: Sales Growth of Vaccines vs. Pharmaceuticals 2004-2013 CHAPTER FOUR: MARKET ANALYSIS Table 4-1: Selected Government Orders for Swine Flu Vaccine Figure 4-1: Doses Ordered as a Percentage of Population, Select Countries (United States, UK, Netherlands, Brazil, Croatia, France) Table 4-2: Swine Flu Vaccine Sales, 2009 Figure 4-2: Estimated Regional Swine Flu Sales, 2009 (NA, EU, ASIA, ROW) Figure 4-3: Delivery System Used (Injectible, Intranasal) Table 4-4: World Cervical CancerVaccine Market (Gardasil and Cervarix) 2004- 2010 Table 4-5: Market Forecast: H1N1 Vaccine sales Table 4-6: Market Forecast: Influenza Vaccine with H1N1 impact Figure 4-5: Market Forecast: Influenza Vaccine with H1N1 Impact Available immediately for Online Download at http://www.marketresearch.com/product/display.asp?productid=2651343 US: 800.298.5699 UK +44.207.256.3920 Int'l: +1.240.747.3093 Fax: 240.747.3004