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© 2015 MapR Technologies 1© 2015 MapR Technologies
Hadoop for Genome Sequencing
© 2015 MapR Technologies 2
Why is Hadoop Considered the Best Platform for
Genomics?
This is an exciting time for those who work in
clinical genomics, as the genomics
sequencing market is experiencing
exponential growth. However, this growth
brings new challenges, especially in terms of
how to properly manage the massive amount
of sequenced human genome data.
© 2015 MapR Technologies 3
Sequencing Costs are Dramatically Decreasing
© 2015 MapR Technologies 4
DNA Sequencing Architecture pre-Hadoop
Storage
write-only
read/write
High-Performance Compute Cluster
Coordinator /
Edge Node
Sequencer
© 2015 MapR Technologies 5
DNA Sequencing Architecture post-Hadoop
Storage
write-only
read/write
High-Performance Compute Cluster
Coordinator /
Edge Node
DNA Sequencer Cluster (e.g. Illumina X-Ten)
HPC bottleneck
Sequencer
back-pressure
© 2015 MapR Technologies 6
Secondary Analytics Can Now Scale Out
HPC
Analytics
Hadoop / Spark
Analytics
© 2015 MapR Technologies 7
Benefits of Hadoop
• Storage and compute on a cost- effective platform
• Overcome bottleneck associated with current HPC( High
Performance Computing) and NAS( Network Attached
Storage) architecture for large scale data processing
• Minimize delays to actual production operations for DNA
sequencing
© 2015 MapR Technologies 8
The MapR Advantage
• Scale Reliability Across the Enterprise
– Advanced multi-tenancy
– Business continuity – HA, DR
• Speed
– 2-7x faster than other Hadoop distributions
– Ultra-fast data ingest (100M data points per sec)
– NFS & R/W file system
• Real-time & Self-Service Data Exploration
– On-the-fly SQL without up-front schema
– Fast lookups and queries
Best Hadoop Platform for Genome Sequencing
Security
Streaming
NoSQL & Search
Provisioning
&
coordination
ML, Graph
W orkflow
& Data Governance
Batch
SQL
INTEGRATED
COMMERCIAL
ENGINES
TOOLSCOMPUTE
ENGINES
Batch
Interactive
Real-time
Online
Others
Management
Operations
Governance
Audits
Security
MapR-FS MapR-DB
MapR Data Platform
© 2015 MapR Technologies 9
Learn More in Our White Paper
Download the Next Generation Genome Sequencing Using MapR white
paper to discover how scale-out Internet architectures can be applied to
clinical genomics.
You’ll learn:
• Why Hadoop is the ideal platform for genomics workflow
processing
• The benefits of moving from academic-style projects to more
commercial platforms in order to achieve scale and economics
• Why the unique capabilities of MapR make it the best solution for
data processing and analytics in genomics
Download Now!

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Hadoop for Genome Sequencing

  • 1. © 2015 MapR Technologies 1© 2015 MapR Technologies Hadoop for Genome Sequencing
  • 2. © 2015 MapR Technologies 2 Why is Hadoop Considered the Best Platform for Genomics? This is an exciting time for those who work in clinical genomics, as the genomics sequencing market is experiencing exponential growth. However, this growth brings new challenges, especially in terms of how to properly manage the massive amount of sequenced human genome data.
  • 3. © 2015 MapR Technologies 3 Sequencing Costs are Dramatically Decreasing
  • 4. © 2015 MapR Technologies 4 DNA Sequencing Architecture pre-Hadoop Storage write-only read/write High-Performance Compute Cluster Coordinator / Edge Node Sequencer
  • 5. © 2015 MapR Technologies 5 DNA Sequencing Architecture post-Hadoop Storage write-only read/write High-Performance Compute Cluster Coordinator / Edge Node DNA Sequencer Cluster (e.g. Illumina X-Ten) HPC bottleneck Sequencer back-pressure
  • 6. © 2015 MapR Technologies 6 Secondary Analytics Can Now Scale Out HPC Analytics Hadoop / Spark Analytics
  • 7. © 2015 MapR Technologies 7 Benefits of Hadoop • Storage and compute on a cost- effective platform • Overcome bottleneck associated with current HPC( High Performance Computing) and NAS( Network Attached Storage) architecture for large scale data processing • Minimize delays to actual production operations for DNA sequencing
  • 8. © 2015 MapR Technologies 8 The MapR Advantage • Scale Reliability Across the Enterprise – Advanced multi-tenancy – Business continuity – HA, DR • Speed – 2-7x faster than other Hadoop distributions – Ultra-fast data ingest (100M data points per sec) – NFS & R/W file system • Real-time & Self-Service Data Exploration – On-the-fly SQL without up-front schema – Fast lookups and queries Best Hadoop Platform for Genome Sequencing Security Streaming NoSQL & Search Provisioning & coordination ML, Graph W orkflow & Data Governance Batch SQL INTEGRATED COMMERCIAL ENGINES TOOLSCOMPUTE ENGINES Batch Interactive Real-time Online Others Management Operations Governance Audits Security MapR-FS MapR-DB MapR Data Platform
  • 9. © 2015 MapR Technologies 9 Learn More in Our White Paper Download the Next Generation Genome Sequencing Using MapR white paper to discover how scale-out Internet architectures can be applied to clinical genomics. You’ll learn: • Why Hadoop is the ideal platform for genomics workflow processing • The benefits of moving from academic-style projects to more commercial platforms in order to achieve scale and economics • Why the unique capabilities of MapR make it the best solution for data processing and analytics in genomics Download Now!