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Lecture14 teratology

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Lecture 14 ESS_2nd semester ,[object Object],[object Object],[object Object],[object Object],[object Object]
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Etiologal factors inducing congenital malformations are usually classified as follows: a) environmental - 7-10 % , environmental factors inducing anomalies are called teratogens, b) genetic - 10-15%, CM are caused by numerical chromosomal abnormalities or by mutant genes c) multifactorial - 20 25 %, CM are caused by action of both previous factors together for cca 50% of CM, the causes are unknown
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[object Object],[object Object],[object Object],[object Object],[object Object],Due an enlargement of the amniotic sac, the extraembryonic coelom disappears and amnion lies to close vicinity of the chorionic sac , b oth membranes ultimately fuse in one common layer known as amniochorionic membrane
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[object Object],[object Object],[object Object],[object Object],the cavities posses a parietal wall lined by mesothelium derived from the somatic mesoderm, and a splanchnic (visceral) wall covered by mesothelium derived from the splanchnic mesoderm
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[object Object],[object Object],[object Object],[object Object],[object Object],DEVELOPMENT OF THE DIGESTIVE SYSTEM: THE STOMODEUM, THE PRIMITIVE GUT AND THE PROCTODEUM
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DE RIVATIVES OF THE PRIMITIVE GUT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Lecture14 teratology

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  • 3. Etiologal factors inducing congenital malformations are usually classified as follows: a) environmental - 7-10 % , environmental factors inducing anomalies are called teratogens, b) genetic - 10-15%, CM are caused by numerical chromosomal abnormalities or by mutant genes c) multifactorial - 20 25 %, CM are caused by action of both previous factors together for cca 50% of CM, the causes are unknown
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