2. Female & Male Hormones
Female Sex Hormones
The ovaries secrete two hormones, oestrogen and
progesterone
Male Sex Hormones
Testosterone & determines the primary and secondary sex
characteristics.
The male reproductive system is controlled by hormones
from the hypothalamus and from the anterior pituitary
gland.
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6. Hormonal control of the female
reproductive cycle.
The two cycles are the ovarian cycle and the
uterine cycle. The cycles are interrelated and
average 28 days.
The ovarian cycle is divided into the follicular
phase and the luteal phase.
During the follicular phase the ovarian follicle
matures primarily in response to FSH. The
follicular phase ends with ovulation and is
dominated by oestrogen.
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7. The uterine cycle is divided into the menstral
phase, the proliferative phase and the secretory
phase.
Menstral – loss of part of the endometrial lining and
blood (menstruation)
Proliferative – endometrial lining thickens and becomes
vascular (primarily in response to oestrogen)
Secretory – endometrial lining becomes lush and moist
from increased secretory activity (primarily in response
to progesterone)
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11. Hormonal and
Menstrual Alterations
Polycystic ovarian syndrome
Leading cause of infertility in the United States
Oligo-ovulation or anovulation
Elevated levels of androgens or clinical signs of
hyperandrogenism and polycystic ovaries
Multifactorial
Hyperinsulinism, hypertension, dyslipidemia
Dysfunction of follicle development
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12. Infection and Inflammation
Pelvic inflammatory disease (PID)
Acute inflammatory disease caused by infection
May involve any organ of the reproductive tract
Salpingitis
Oophoritis
Sexually transmitted diseases migrate from the
vagina to the upper genital tract
Polymicrobial infection
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15. Pelvic Relaxation Disorders
The bladder, urethra, and rectum are supported
by the endopelvic fascia and perineal muscles
The muscular and fascial tissue loses tone and
strength with aging
Fails to maintain organs in proper position
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18. Benign Growths and
Proliferative Conditions
Endometriosis
Presence of functioning endometrial tissue or
implants outside the uterus
Responds to hormone fluctuations of the menstrual
cycle
Possible causes
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Retrograde menstruation, spread through vascular or
lymphatic systems, stimulation of multipotential
epithelial cells on reproductive organs or genetic
predisposition
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21. Breast Cancer
Reproductive factors
Hormonal factors
Environmental factors and lifestyle
Radiation
Diet
Chemicals (xenoestrogens)
Physical activity
Familial factors and tumor-related genes
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22. Breast Cancer
Manifestations
Painless lump, dimpling of skin, edema
Treatment
Based on stage of cancer
Surgery, radiation, chemotherapy, hormone
therapy, biologic therapy and bone marrow
transplantation
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