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TRANSFERENCIA DE
TECNOLOXIA E FOMENTO DO

EMPRENDEMENTO
BIOTECNOLOGICO EN ISRAEL

© Kerentech SL

1
OFFICE OF THE ISRAEL CHIEF
SCIENTIST PROGRAMS

Generic
Technologies

Applied
Research

Magnet

Nofar

Magneton

Kamin

Pre-Seed
Tnufa

EarlyStage

Seed
Technological
Incubators
Program

Early-Stage
Fund

Growth
R&D
Fund

Bi-National & Multinational
Funds and agreements
2
GOVERNMENT INVOLVEMENT
The Technological Incubators
Program is a government response
to a market failure.

Warning!!! High Risk
Too Innovative

• Market Failure
–

Early stage, high risk, innovative technological companies, can not raise money from the private
sector.

• Government Response
–

Bridging the gap through the Technological Incubators Program

3
INCUBATOR’S GOAL
Technological Incubators are today private
companies for profit
Main goal: Developing innovative
technological ideas into start-ups
and leading them towards first round
investment.
4
Appropriate
facilities and
infra-structure
for R&D
Inter-tenant
synergism

Connections to
potential
customers,
partners and
investors

Financing

WHAT DOES AN INCUBATOR
OFFER TO ENTREPRENEURS?
Central
administrative
services

Professional &
Business
guidance

Management &
Technical
assistance

5
GOVERNMENT SUPPORT
• Average budget of project: $500K
– Government grant: 85% of budget
– Incubator’s investment: 15% of budget

• Payback: 3% royalties from revenue
• Incubator Term: 2-3 years
• Extended support to Biotech/Pharma & CleanTech projects (budget, optional 3rd year)
• Extended support for projects initiated in
peripheral regions
• Annual Government Budget to the Program:
~$50M
6
THE INCUBATORS FRANCHISE
MODEL

• Franchise Term: 8 years with performance
based milestones

• Tender: 1 year before Franchise end date

7
INCUBATOR APPROVAL PROCESS
• License Tender Publication
• Q&A
• Application Submittal
• Applications Review
• Applications Assessment
• Incubators Committee Decision
• Initiation
8
LICENSEE BENEFITS
• 8 Years license
• Low risk (majority of risk absorbed by the
government)
• Incentives (up to 50% shares in every
company for a 15% investment)
• Grant payback by the companies in case
of success and revenue generation only
• Certainty, Flexibility
9
PROJECT CRITERIA

Innovation
&
Uniqueness

Early Stage,
High Risk

Significant
Market
Potential

IP
Protection

Leading
Team

Feasibility
in meeting
significant
milestone

10
PROJECT APPROVAL PROCESS
Approaching
an Incubator

Incubator
Evaluation &
Approval (1%3%)

Submittal to
OCS

OCS
Evaluation &
Approval
(80%)

Project
Initiation

11
PROGRAM OBJECTIVES
• Primary Objective
– Creating new startup companies that would not start otherwise

• Secondary Objectives
–
–
–
–

Transferring technology from research institutes into the industry
Creating industrial R&D activity in peripheral regions
Providing deal flow for the venture capital industry
Creating technological entrepreneurial culture

12
Program Milestones
• 1991: Establishment of program
• 2002: Initiating the Privatization Process
• 2005: Establishing a designated biotech incubator
in Jerusalem
• 2008: Establishing 2 technology based industrial
incubators in Haifa and Arad
• 2010: End of Privatization Process
• 2011: Reforms in the basic models of the
Incubators Program
• 2012: Implementation of the tendering process for
selecting new licensees
13
Volume of Operation
• Incubators
– 22 Technological Incubators
– 1 Biotech Incubator
– 1 Technology based Industrial Incubator

• Incubated Companies
– Approximately 70 – 80 new startup companies every year
– ~175 startup companies operating at any given time, ~90%
successfully complete the incubator term

14
INCUBATORS NETWORK
Gush Segev
Haifa
Nazareth
Caesarea
Netanya

Tel Aviv

Yoq’neam

Ariel

Ashdod
Jerusalem

Ashqelon

Gush Ezion
Beersheba

15
FIELDS OF ACTIVITY |INCUBATED COMPANIES 2012
Others, 3%

ICT, 32%

Clean-Tech,
15%

Medical
Device, 42%

Bio-Pharma,
8%

16
GOVERNMENT FUNDING VS PRIVATE INVESTMENTS | 1991 2012
Government Funding

2012

2011

2010

2009

2008

2007

2006

2005

2004

2003

2002

2001

2000

1999

1998

1997

1996

1995

1994

1993

1992

1991

3,750,000
3,500,000
3,250,000
3,000,000
2,750,000
2,500,000
2,250,000
2,000,000
1,750,000
1,500,000
1,250,000
1,000,000
750,000
500,000
250,000
0

Private Investments

17
HIGHLIGHTS
•
•
•
•
•
•

The incubators program is the primary “Manufacturer”
of start-ups in Israel
The incubators program is the only opportunity for
early-stage, high-risk innovative projects that are not
yet able to raise money from the private sector
The incubators program is an important source of
deal-flow for the venture capital industry
The incubators program is especially important in times of
economic crisis
The incubators program has a significant impact on the lifescience industry in Israel
The incubators program has a crucial role in developing an
entrepreneurship culture in Israel
18
WORLD INNOVATION CLUSTERS
London
Paris

Silicon
Valley

Skolkovo

Boston

Beijing

Israel

Bangalore

Source: MIT Technology Review
19
SILICON VALLEY

*

• Venture Capital : $11.2 billion
• Top Companies: Google, Apple
• Key Facts:
– 64% Foreign Workers
– 17 IPOs in 2012

•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
20
BOSTON

*

• Venture Capital : $3.6 billion
• Top companies: Akamai, Genzyme
• Key facts:
– Most US biomedical funding
– 85 Colleges and Universities

•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
21
TECHCITY LONDON

*

• Venture Capital: $161 million
• Top CompaniesL Techstars Last.fm
• Key facts:
– Startup initiative created in 2010
– 140 Technology companies
– Tax breaks for private investors

•
•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
Government Cluster
22
PARIS SACLAY
• Government Funding: $3.25 billion
• Top Companies: EADS, Siemens
• Key Facts:
– Construction began in 2013
– Two-square-kilometer campus
– Merging Six engineering schools

•
•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
Government Cluster
23
ISRAEL

*

• Venture Capital: $1 billion
• Top Companies: Waze, Teva
• Key facts:
– 230000 high-tech workers
– Compulsory military training
– $25 billion in technology exports

•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
24
SKOLKOVO INNOVATION CITY

*

• Government funding: $2.5 billion
• Top Companies: IBM, Rusnano
• Key Facts:
– Founded in 2010
– 3.64 square kilometer innovation center
– University designed by MIT

•
•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
Government Cluster
25
BANGALORE

*

• Venture Capital: $300 million
• Top Companies: Infosys, Wipro
• Key Facts:
– Internet users up 26% per year
– $3876 per capita income ( India)
– Over 10.000 local milionaires

•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
26
BEIJING

*

• Venture Capital: $1.4 billion
• Top companies : Baidu, Lenovo
• Key facts:
– 70 Colleges and Universities
– 30% of China’s Venture Funding
– 14.5 million Internet users

•
•
•
•

Strong IP Protection ©
Good weather ☼
Liberal immigration laws m
Entrepreneurial Culture A
27
Bangalore

Beijing

GF(M)
$2500

VC(M)
$300

VC(M)
$1400

Waze,
Teva

IBM,
Rusnano

Infosys
Wipro

Baidu,
Lenovo

-230000
high-tech
workers
-Compulsory
military
training
-$25 billion in
tech. exports

-Founded
2010
-3.46 km2
campus
-University
designed by
MIT

Internet
users:Δ=26%
$3876 p.c.
income/y
Over
10000local
millionaires

70 colleges
and
Universities
30% China
VC funding
14.5M
internet users

Sillicon
Valley

Boston

TechCity Paris
London Saclay

Israel

Skolkovo

VC (M)
$11200

VC (M)
$3600

VC (M)
$161

VC(M)
$1000

Google,
Apple

Akamai,
Genzyme

Techstars EADS,
Last.fm
Siemens

-64%
Foreign
workers
-17 IPOs
in 2012

-Most US
Biomed
funding
-85
Colleges &
Universities

- Startup
initiative
created in
2010
-140 tech Cos.
-Tax breaks
for private
investors

GF(M)
$3250

Construction:
2013
- 2km2
campus
- Merging 6
engineering
schools

Innovation
City

© ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A

VC= Venture Capital; GF= Government Funds

*
28
CONTACT
19 Ha Lamed Hey
93661 Jerusalem
Israel

Muntaner 200 atico
08036 Barcelona
Spain

info@kerentech.com
www.kerentech.com

29

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Israel's Technological Incubators Program fosters biotech entrepreneurship

  • 1. TRANSFERENCIA DE TECNOLOXIA E FOMENTO DO EMPRENDEMENTO BIOTECNOLOGICO EN ISRAEL © Kerentech SL 1
  • 2. OFFICE OF THE ISRAEL CHIEF SCIENTIST PROGRAMS Generic Technologies Applied Research Magnet Nofar Magneton Kamin Pre-Seed Tnufa EarlyStage Seed Technological Incubators Program Early-Stage Fund Growth R&D Fund Bi-National & Multinational Funds and agreements 2
  • 3. GOVERNMENT INVOLVEMENT The Technological Incubators Program is a government response to a market failure. Warning!!! High Risk Too Innovative • Market Failure – Early stage, high risk, innovative technological companies, can not raise money from the private sector. • Government Response – Bridging the gap through the Technological Incubators Program 3
  • 4. INCUBATOR’S GOAL Technological Incubators are today private companies for profit Main goal: Developing innovative technological ideas into start-ups and leading them towards first round investment. 4
  • 5. Appropriate facilities and infra-structure for R&D Inter-tenant synergism Connections to potential customers, partners and investors Financing WHAT DOES AN INCUBATOR OFFER TO ENTREPRENEURS? Central administrative services Professional & Business guidance Management & Technical assistance 5
  • 6. GOVERNMENT SUPPORT • Average budget of project: $500K – Government grant: 85% of budget – Incubator’s investment: 15% of budget • Payback: 3% royalties from revenue • Incubator Term: 2-3 years • Extended support to Biotech/Pharma & CleanTech projects (budget, optional 3rd year) • Extended support for projects initiated in peripheral regions • Annual Government Budget to the Program: ~$50M 6
  • 7. THE INCUBATORS FRANCHISE MODEL • Franchise Term: 8 years with performance based milestones • Tender: 1 year before Franchise end date 7
  • 8. INCUBATOR APPROVAL PROCESS • License Tender Publication • Q&A • Application Submittal • Applications Review • Applications Assessment • Incubators Committee Decision • Initiation 8
  • 9. LICENSEE BENEFITS • 8 Years license • Low risk (majority of risk absorbed by the government) • Incentives (up to 50% shares in every company for a 15% investment) • Grant payback by the companies in case of success and revenue generation only • Certainty, Flexibility 9
  • 10. PROJECT CRITERIA Innovation & Uniqueness Early Stage, High Risk Significant Market Potential IP Protection Leading Team Feasibility in meeting significant milestone 10
  • 11. PROJECT APPROVAL PROCESS Approaching an Incubator Incubator Evaluation & Approval (1%3%) Submittal to OCS OCS Evaluation & Approval (80%) Project Initiation 11
  • 12. PROGRAM OBJECTIVES • Primary Objective – Creating new startup companies that would not start otherwise • Secondary Objectives – – – – Transferring technology from research institutes into the industry Creating industrial R&D activity in peripheral regions Providing deal flow for the venture capital industry Creating technological entrepreneurial culture 12
  • 13. Program Milestones • 1991: Establishment of program • 2002: Initiating the Privatization Process • 2005: Establishing a designated biotech incubator in Jerusalem • 2008: Establishing 2 technology based industrial incubators in Haifa and Arad • 2010: End of Privatization Process • 2011: Reforms in the basic models of the Incubators Program • 2012: Implementation of the tendering process for selecting new licensees 13
  • 14. Volume of Operation • Incubators – 22 Technological Incubators – 1 Biotech Incubator – 1 Technology based Industrial Incubator • Incubated Companies – Approximately 70 – 80 new startup companies every year – ~175 startup companies operating at any given time, ~90% successfully complete the incubator term 14
  • 15. INCUBATORS NETWORK Gush Segev Haifa Nazareth Caesarea Netanya Tel Aviv Yoq’neam Ariel Ashdod Jerusalem Ashqelon Gush Ezion Beersheba 15
  • 16. FIELDS OF ACTIVITY |INCUBATED COMPANIES 2012 Others, 3% ICT, 32% Clean-Tech, 15% Medical Device, 42% Bio-Pharma, 8% 16
  • 17. GOVERNMENT FUNDING VS PRIVATE INVESTMENTS | 1991 2012 Government Funding 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 3,750,000 3,500,000 3,250,000 3,000,000 2,750,000 2,500,000 2,250,000 2,000,000 1,750,000 1,500,000 1,250,000 1,000,000 750,000 500,000 250,000 0 Private Investments 17
  • 18. HIGHLIGHTS • • • • • • The incubators program is the primary “Manufacturer” of start-ups in Israel The incubators program is the only opportunity for early-stage, high-risk innovative projects that are not yet able to raise money from the private sector The incubators program is an important source of deal-flow for the venture capital industry The incubators program is especially important in times of economic crisis The incubators program has a significant impact on the lifescience industry in Israel The incubators program has a crucial role in developing an entrepreneurship culture in Israel 18
  • 20. SILICON VALLEY * • Venture Capital : $11.2 billion • Top Companies: Google, Apple • Key Facts: – 64% Foreign Workers – 17 IPOs in 2012 • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A 20
  • 21. BOSTON * • Venture Capital : $3.6 billion • Top companies: Akamai, Genzyme • Key facts: – Most US biomedical funding – 85 Colleges and Universities • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A 21
  • 22. TECHCITY LONDON * • Venture Capital: $161 million • Top CompaniesL Techstars Last.fm • Key facts: – Startup initiative created in 2010 – 140 Technology companies – Tax breaks for private investors • • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A Government Cluster 22
  • 23. PARIS SACLAY • Government Funding: $3.25 billion • Top Companies: EADS, Siemens • Key Facts: – Construction began in 2013 – Two-square-kilometer campus – Merging Six engineering schools • • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A Government Cluster 23
  • 24. ISRAEL * • Venture Capital: $1 billion • Top Companies: Waze, Teva • Key facts: – 230000 high-tech workers – Compulsory military training – $25 billion in technology exports • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A 24
  • 25. SKOLKOVO INNOVATION CITY * • Government funding: $2.5 billion • Top Companies: IBM, Rusnano • Key Facts: – Founded in 2010 – 3.64 square kilometer innovation center – University designed by MIT • • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A Government Cluster 25
  • 26. BANGALORE * • Venture Capital: $300 million • Top Companies: Infosys, Wipro • Key Facts: – Internet users up 26% per year – $3876 per capita income ( India) – Over 10.000 local milionaires • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A 26
  • 27. BEIJING * • Venture Capital: $1.4 billion • Top companies : Baidu, Lenovo • Key facts: – 70 Colleges and Universities – 30% of China’s Venture Funding – 14.5 million Internet users • • • • Strong IP Protection © Good weather ☼ Liberal immigration laws m Entrepreneurial Culture A 27
  • 28. Bangalore Beijing GF(M) $2500 VC(M) $300 VC(M) $1400 Waze, Teva IBM, Rusnano Infosys Wipro Baidu, Lenovo -230000 high-tech workers -Compulsory military training -$25 billion in tech. exports -Founded 2010 -3.46 km2 campus -University designed by MIT Internet users:Δ=26% $3876 p.c. income/y Over 10000local millionaires 70 colleges and Universities 30% China VC funding 14.5M internet users Sillicon Valley Boston TechCity Paris London Saclay Israel Skolkovo VC (M) $11200 VC (M) $3600 VC (M) $161 VC(M) $1000 Google, Apple Akamai, Genzyme Techstars EADS, Last.fm Siemens -64% Foreign workers -17 IPOs in 2012 -Most US Biomed funding -85 Colleges & Universities - Startup initiative created in 2010 -140 tech Cos. -Tax breaks for private investors GF(M) $3250 Construction: 2013 - 2km2 campus - Merging 6 engineering schools Innovation City © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A © ☼m A VC= Venture Capital; GF= Government Funds * 28
  • 29. CONTACT 19 Ha Lamed Hey 93661 Jerusalem Israel Muntaner 200 atico 08036 Barcelona Spain info@kerentech.com www.kerentech.com 29