Hypoglycemia and hyperglycemia in the pregnanat patient
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ClinicalStudy Myo-Inositol in the Treatment of Teenagers Affected by PCOS
LaliPkhaladze,LudmilaBarbakadze,andNanaKvashilava ArchilKhomasuridzeInstituteofReproductology,0112Tbilisi,Georgia CorrespondenceshouldbeaddressedtoLaliPkhaladze;lpkhaladze@yahoo.com Received3June2016;Revised28July2016;Accepted1August2016 AcademicEditor:FabioFacchinetti Copyright©2016LaliPkhaladzeetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Objective. To compare the effectiveness of myo-inositol (MI) and oral contraceptive pills (OCPs) in monotherapy and MI in combinationwithOCPsinthetreatmentofteenagersaffectedbypolycysticovarysyndrome(PCOS).Methods.61adolescentgirls aged 13â19 years, with PCOS, were involved in the prospective, open-label study. Patients were randomized into three groups: I group, 20 patients receiving drospirenone 3mg/ethinyl estradiol 30íg; II group, 20 patients receiving 4g myo-inositol plus 400mg folic acid; III group, 21 patients receiving both medications. Results. After receiving MI significant reduction in weight, BMI, glucose, C-peptide, insulin, HOMA-IR, FT, and LH was detected. The levels of SHBG, TT, FAI, DHEA-S, and AMH did not change statistically significantly. After receiving OCPs weight and BMI slightly increased, but metabolic parameters did not change.CombinationofMIandOCPsdidnotchangeweightandBMI,butreductioninC-peptide,insulin,andHOMA-IRwas detected.TT,FT,FAI,DHEA-S,LH,andAMHlevelsdecreasedandSHBGincreased.Conclusions.AdministrationofMIisasafe andeffectivemethodtopreventandcorrectmetabolicdisordersinteenagersaffectedbyPCOS.WithcombinationofMIandOCPs antiandrogeniceffectsareenhanced,negativeimpactofOCPsonweightgainisbalanced,andmetabolicprofileisimproved.
Clinical study myo inositol in the treatment of teenagers affected by pcos
Clinical study myo inositol in the treatment of teenagers affected by pcosAl-YAQIN DIAGNOSTIC ULTRASONIC CLINIC BAGHDAD
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Was ist angesagt?
ClinicalStudy Myo-Inositol in the Treatment of Teenagers Affected by PCOS
LaliPkhaladze,LudmilaBarbakadze,andNanaKvashilava ArchilKhomasuridzeInstituteofReproductology,0112Tbilisi,Georgia CorrespondenceshouldbeaddressedtoLaliPkhaladze;lpkhaladze@yahoo.com Received3June2016;Revised28July2016;Accepted1August2016 AcademicEditor:FabioFacchinetti Copyright©2016LaliPkhaladzeetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttributionLicense, whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperlycited. Objective. To compare the effectiveness of myo-inositol (MI) and oral contraceptive pills (OCPs) in monotherapy and MI in combinationwithOCPsinthetreatmentofteenagersaffectedbypolycysticovarysyndrome(PCOS).Methods.61adolescentgirls aged 13â19 years, with PCOS, were involved in the prospective, open-label study. Patients were randomized into three groups: I group, 20 patients receiving drospirenone 3mg/ethinyl estradiol 30íg; II group, 20 patients receiving 4g myo-inositol plus 400mg folic acid; III group, 21 patients receiving both medications. Results. After receiving MI significant reduction in weight, BMI, glucose, C-peptide, insulin, HOMA-IR, FT, and LH was detected. The levels of SHBG, TT, FAI, DHEA-S, and AMH did not change statistically significantly. After receiving OCPs weight and BMI slightly increased, but metabolic parameters did not change.CombinationofMIandOCPsdidnotchangeweightandBMI,butreductioninC-peptide,insulin,andHOMA-IRwas detected.TT,FT,FAI,DHEA-S,LH,andAMHlevelsdecreasedandSHBGincreased.Conclusions.AdministrationofMIisasafe andeffectivemethodtopreventandcorrectmetabolicdisordersinteenagersaffectedbyPCOS.WithcombinationofMIandOCPs antiandrogeniceffectsareenhanced,negativeimpactofOCPsonweightgainisbalanced,andmetabolicprofileisimproved.
Clinical study myo inositol in the treatment of teenagers affected by pcos
Clinical study myo inositol in the treatment of teenagers affected by pcosAl-YAQIN DIAGNOSTIC ULTRASONIC CLINIC BAGHDAD
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Was ist angesagt? (20)
Clinical study myo inositol in the treatment of teenagers affected by pcos
Clinical study myo inositol in the treatment of teenagers affected by pcos
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Estimation of Fetal Size and Weight using Various Formulas
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Recurrent pregnancy loss Presentation by Dr.Laxmi Shrikhande
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