Este documento resume la enfermedad trofoblástica gestacional, incluyendo molas hidatiformes completas y parciales, coriocarcinoma e invasión trofoblástica. Describe las características clínicas, histopatológicas, factores de riesgo, diagnóstico, tratamiento y pronóstico de estas afecciones relacionadas con la placenta.
1. UNIVERSIDAD DE CARTAGENA FACULTAD DE MEDICINA DEPARTAMENTO DE GINECOLOGIA Y OBSTETRICIA ENFERMEDAD TROFOBLASTICA GESTACIONAL Docente: Dr. JHON SAMPER Presentado: JOSE CHICO TOLOSA RESIDENTE II AÑO
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7. BIOLOGIA MOLECULAR DE LA ENFERMEDAD TROFOBLASTICA GESTACIONAL Epidemiology and etiology of Gestational trophoblastic Disease. The Lancet Oncology. Volume 4, Number11, November2003 Upregulated None Upregulated RB Upregulated None Upregulated p21 Upregulated None Upregulated p53 Tumor suppressor genes Upregulated None Upregulated BCL2 Upregulated None Upregulated c-ERBB2 Upregulated Upregulated Upregulated MDM2 Oncogenes Choriocarcinoma Partial mole Complete mole None, no difference with normal trophoblasts; RB, retinoblastoma; EGF, epidermal growth factor. Table 2. Oncogens, tumor suppressor genes, and other molecular features possibly involved in the pathogenesis of complete and partial mole, and choriocarcinoma
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11. MOLA COMPLETA IMAGEN MACROSCOPICA, MICROSCOPICA, MECANISMO BASICO Choriocarcinoma and Gestacional Trophoblastic Disease. Obstet Gynecol Clin N Am 32(2005)661-684
24. MOLA COMPLETA Y PARCIAL TABLA COMPARATIVA Diagnosis and Treatment of Gestational trophoblastic Disease:ACOG Practice Bulletin N 53. Gynecologyc Oncology. Issue3, June 2004,(575-585).
43. SISTEMA DE PUNTUACION RESPUESTA A QUIMIOTERAPIA <4 Bajo riesgo; 5-7 Riesgo Medio; >8 Riesgo Alto The new FIGO 2000 staging and risk factor scoring system for Gestational Trophoblastic Gestational Disease: Description and critical assesment. Int J Gynecol Cancer 2001;11(1):73-7