Phagocytosis Hodgkin's Disease Sarcoidosis

1. Phagocytosis, hodgkin’s disease, and sarcoidosis Presented by Jamecia McFarlin

2. What is phagocytosis? Phagocytosis is a process the human body uses to destroy dead or foreign cells. Phagocytosisis a form of endocytosis. Phagocytosis can also be classified as the engulfing and ingestion of bacteria or other foreign bodies by phagocytes.

3. The process of phagocytosis In the process of phagocytosis the cell changes shape by sending out projections which are called pseudpodia (false feet). The phagocytic cell such as a macrophage may be attracted to a particle like a bacteria or virus by chemical attractant. This process is called chemotaxis (movement toward a source of chemical attractant). The phagocytic cell sends out membrane projections that make contact with some particle.

4. The process continued Some sort of receptor lagan interaction occurs between the phagocytic cell surface and the particle that will be ingested. The pseudopodia then surround the particle and when the plasma membrane of the projection meet membrane fusion occurs. This results in the formation of an intracellular vesicle.

5. Visual phagocytosis

6. What is hodgkin’sdiesease? Hodgkin's disease is a type of lymphoma. Lymphoma is cancer of lymph tissue found in the lymph nodes, spleen, liver, and bone marrow. The first sign of Hodgkin's disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver or bone marrow. Hodgkin’s disease is rare. The cause is unknown.

7. Symptoms of hodgkin’s disease Symptoms Include: painless swelling of the lymph nodes in the neck, armpits, or groin fever and chills night sweats weight loss loss of appetite itchy skin

8. What is sarcoidosis? Sarcoidosisis a disease of unknown cause that leads to inflammation. It can affect various organs in the body. Sarcoidosis can affect any organ in your body. However, it's more likely to occur in some organs than in others. The disease usually starts in the lungs, skin, and/or lymph nodes (especially the lymph nodes in your chest). The disease also often affects the eyes and the liver. Although less common, sarcoidosis can affect the heart and brain, leading to serious complications.

9. Symptoms of Sarcoidosis If many granulomas form in an organ, they can affect how the organ works. This can cause signs and symptoms. Signs and symptoms vary depending on which organs are affected. Many people who have sarcoidosis have no symptoms or mild symptoms.

10. The out come of sarcoidosis The outcome of sarcoidosis varies. Many people recover from the disease with few or no long-term problems. More than half of the people who have sarcoidosis have remission within 3 years of diagnosis. "Remission" means the disease isn't active, but it can return. Two-thirds of people who have the disease have remission within 10 years of diagnosis. Relapse (return of the disease) 1 or more years after remission occurs in less than 5 percent of patients. Sarcoidosis leads to organ damage in about one-third of the people diagnosed with the disease. Rarely, sarcoidosis can be fatal. Death usually is the result of complications with the lungs, heart, or brain.

11. Visual of sarcoidosis

12. The end!!!!