Chemical contaminants form a vast chemical soup in the Great Lakes, and from available data, we know exposure may be cause for concern. This workshop will discuss the threat of “emerging contaminants” in the Lakes, as well as give an overview of research, policy implications and recommendations for moving forward.
10. A Biological Target: Cell Receptors Modified from: Cell-Cell Interactions Category: Basic Biology • Science Education Posted on: November 23, 2006, by Coturnix http://scienceblogs.com/clock/2006/11/cellcell_interactions.php
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13. Chemicals with potential for synergistic or additive environmental effects: Conceptual example Industry and Agriculture Pharmaceuticals and Personal Care Products (PPCPs) Action : Endocrine Disruption, Antimicrobial, etc.
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15. Evaluating impact of contaminants on the environment and human health Environmental Sciences: Contaminant Transport and Distribution Biological Sciences: Ecotoxicology Biomedical Sciences: Human Toxicology
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19. A complex relationship with the natural world ! Environmental Life-Cycle of Pharmaceuticals by CG Daughton, US EPA, 2006
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Hinweis der Redaktion
Coprostanol: cholesterol metabolite and biomarker of fecal contamination Cholesterol: N-N-diethyltoluamide: DEET Caffeine: natural pesticide; nonselective adenosine receptor antag & phoshpodiesterase inhibitor Tri(2-chloroethyl) phosphate: flame retardant Triclosan: antibacterial & antifungal agent in soap, toothpaste, mouthwash, etc. 4-Nonylphenol: degradation product from detergents 4-Nonylphenol monoethoxylate: degradation product from detergents Ethanol 2-butoxy-phosphate: pesticide 4-Octylphenol monoethoxylate: probably from detergent Bisphenol A – used to make plastics (polycarbonates); estrogenic Cotinine – nicotine metabolite; activates nicotine receptors 4-Nonylphenol diethoxylate – degradation product from detergents 5-methyl-1H-benzotriazole: Fluoranthene: polycyclic aromatic hydrocarbon (PAH); combustion; carcinogen 1,7-Dimethylxanthine: caffeine metabolite; Pyrene: Polycyclic aromatic hydrocarbon (PAH); combustion Trimethoprim: antibiotic; dihydrofolate reductase inhibitor; urinary tract infections 1,4-Dichlorobenzene: used in moth balls & urinal cakes (replaces naphthalene) Diazinon: organophosphate insecticide; inhibits acetylcholinesterase 4-Methyl phenol: cresols; used to dissolve other chemicals, make insecticides Acetominophen: Tylenol Tetrachloroethylene: dry cleaning fluid; group 2A carcinogen 4-Octylphenol diethoxylate: detergent product Erythromycin: antibiotic Estriol: produced during pregnancy by placenta; bioidentical hormone therapy NO longer used in U.S. as of 2008 Linocmycin: antibiotic Sulfamethoxazole: antibiotic (sulfonamide) Phthalic anhydride: plasticizer for plastics; probably endocrine disruptor Carbaryl: carbamate insecticide; acetylcholinesterase inhibitor; third most used insecticide in U.S. – agriculture, gardens, forestry, etc.; probable carcinogen