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Mobile Health:
Highlights and Future Directions
           Audie A. Atienza, PhD
      Senior Health Technology Advisor
  Department of Health and Human Services
           Office of the Secretary

             Behavior Scientist
         National Cancer Institute
        National Institutes of Health

              October 2011
       HHS New Media Webinar Series
Before there were cell phones, there
was…
Who was the real hero in Star Wars?
                              Built-In Sensor for
                              Environmental Scan




                                                    Talk with other
                                                    computer systems
                                                    and optimize
                                                    performance




                             Store and
                             communicate
                             critical information
The Tale of 2 Apps
   Electric street lamp:
    “Electricity is not in any sense a necessity, and under no conditions is it
    universally used by the people of a community. It is but a luxury enjoyed by a
    small proportion of the members of any municipality, and yet if the plant be owned
    and operated by the city, the burden of such ownership and operation must be
    borne by all the people through taxation. Now, electric light is not a necessity
    for every member of the community. It is not the business of any one to see that
    I use electricity, or gas, or oil in my house, or even that I use any form of artificial
    light at all.” (Oct. 24, 1905, Richmond, Virginia, Times-Dispatch, by Henry
    Anderson). http://publicola.com/2009/12/11/the-killer-app-of-1900-2/
   Ringtones:
    “Ringtones were super-hot in the middle of last decade, as everyone started to get
    cellphones, and have since fallen in popularity.”
    http://www.businessinsider.com/chart-of-the-day-remember-ringtones-2010-12
The Mobile Revolution




Mobile technology is everywhere!!!
“The trend is indisputable: Broadcast television viewership is declining, and it has
been for the past two decades. But since the birth of the iPhone and the Android
operating system, mobile data use has exploded. By 2015 traffic will be some 20
times its 2010 level.”

--Sources: FCC, Spectrumwiki, Nielsen, CTIA, National Association of Broadcasters,
Cisco, Rysavy Research

                         Fortune Magazine, July 27, 2011
http://tech.fortune.cnn.com/2011/07/27/spectrum-squeeze-battle-for-bandwidth/
http://www.washingtonpost.com/blogs/post-tech/post/number-of-cell-phones-
exceeds-us-population-ctia-trade-group/2011/10/11/gIQARNcEcL_blog.html?hpid=z3
http://www.ctia.org/advocacy/research/index.cfm/aid/10323
http://www.pewinternet.org/~/media//Files/Reports/2010/PIP_Mobile_Access_2010.pdf
http://www.pewinternet.org/~/media//Files/Reports/2010/PIP_Mobile_Access_2010.pdf
http://www.pewinternet.org/~/media/Files/Reports/
2010/PIP_Mobile_Health_2010.pdf




“…57% of American adults have a wireless connection and
use a laptop or a cell phone to access the internet…78% of
wireless internet users have looked online for health
information…”
www.pewinternet.org/~/media//Files/.../2010/PIP_
Mobile_Health_2010.pdf
http://www.ihealthbeat.org/articles/2011/10/21/report-
26-of-adults-use-mobile-phones-to-access-health-data.aspx
http://www.itu.int/ITU-D/ict/statistics/material/graphs/2010/Cellular_signal_03-09.jpg
http://www.itu.int/ITU-D/ict/statistics/material/graphs/2010/Mobile_cellular_00-05-10.jpg
50+ Case Studies Described




http://www.unfoundation.org/global-issues/technology/mhealth-report.html
Developing Countries




Developed Countries
Remember 2007…




         June 2007, first iPhones released
     October 2008, first Android phone released

In less than 5 years, iPhones and Android phones have
                    become prolific
2009: 1.5 Trillion Text Messages Sent in US
   4.1 billion SMS messages sent daily
                Game Changer!

  Consumer Centered & Driven Change
What is mHealth?
Definitions – Helpful???
   mHealth: Using mobile communications—such as PDAs and mobile phones—for
    health services and information (UN Foundation;
    http://www.unfoundation.org/global-issues/technology/mhealth-report.html)

   mHealth stands for mobile-based or mobile-enhanced health solutions, or the idea
    that global wireless networks and mobile devices (cellphones, smartphones,
    mobile-enabled diagnostic devices) are powerful vehicles for delivering innovative
    medical and health services to the farthest reaches of the globe (mHealth Alliance,
    http://www.mhealthalliance.org/about/frequently-asked-questions)

   mHealth: emerging mobile communications and network technologies for
    healthcare (Istepanian et al. 2005)

   (Mobile-HEALTH) An umbrella term for wireless devices that are used in
    healthcare. It includes mobile monitors worn by patients as well as smartphones
    that physicians and nurses use to obtain and disseminate information. (PC
    Magazine;
    http://www.pcmag.com/encyclopedia_term/0,2542,t=mHealth&i=61665,00.asp)

   Mobile health decouples time and space to assure the best state of health for the
    individual and the population (Group 4AM Session; http://www.scribd.com)

                                  No consensus!!
Eric Dishman on mHealth
Concepts like "home health" and "wireless" and "smart phone" and
"telehealth" are being bandied about as if they are all the same
thing, under the rubric of "mHealth," without much distinction
between these very different capabilities, value propositions, and
markets. Methinks we doth proclaim too much!

I am becoming worried that we don't really know what each other is
talking about when we say "mHealth."

If "mHealth" is all of these things and more....if "mHealth" is
everything...then it is nothing. The phrase has become so slippery,
so ubiquitous as to become almost useless. We must be more
careful in defining and aligning what we're talking about, and I
encourage these various workshops and organizers to spend some
time clarifying and specifying what's at play here.


  http://blogs.intel.com/healthcare/2010/08/the_hype_and_hope_of_mhealth.php
The critical aspects of mobile health is
    the use of MOBILE technology

 “not all mobile health is wireless” and “not all wireless
                     health is mobile”.
   Don Jones, Vice President, Business Development,
           Health & Life Sciences at Qualcomm,
  http://mobihealthnews.com/8997/2010-operators-payers-finally-interested-in-mhealth/
mHealth tools include:
   Health Text Messaging (feature & smart phones)
   Smart Phone Apps/ Tablet Apps
       Native App, Web-Based App, vs. Hybrid App
   Mobile Web
   Ambulatory Monitoring
       Heart Rate, Blood Pressure, GSR, Glucose
   Motion Sensors
       Pedometers, Accelerometers, Gyroscopes
   Body Area Networks
   Global Positioning Systems
   Portable Point of Care Diagnostic Devices
   Mobile Games for Health
HHS Higlights:
mHealth Activities
HHS Text4Health Task Force formed in November 2010




    See - http://www.hhs.gov/open/initiatives/mhealth/recommendations.html
Health Text Messaging (examples)

   CDC Mobile Tips & Alerts
       http://www.cdc.gov/mobile/
   CDC NHANES Text Message Pilot
   NCI SmokeFreeTxt
       http://smokefree.gov/smokefreetxt/
   NIH funded research
       e.g., mDiet (PI: Kevin Patrick)
   ‘text4baby’ program
       http://www.text4baby.org
HHS Mobile Apps (examples)
   AHRQ Electronic Preventive Services Selector-ePSS
       http://itunes.apple.com/us/app/ahrq-epss/id311852560?mt=8
   HRSA Find a Health Clinic
       http://www.hrsa.gov/about/mobile/
   NICHD/NLM - Embryo
       http://itunes.apple.com/app/embryo/id422337604
   NIH - My Dietary Supplements (MyDS)
       http://ods.od.nih.gov/about/mobile/aboutmyds.aspx
   NLM Mobile Apps
       http://www.nlm.nih.gov/mobile/
   SAMHSA Treatment Locator
       http://apps.usa.gov/samhsa-treatment-locator/
HHS Mobile Web (examples)
   AIDS.gov Mobile
       http://m.aids.gov/
   CDC Mobile - Hurricane Recovery
       http://www.bt.cdc.gov/mobile.asp
   HRSA Find a Health Clinic
       http://www.hrsa.gov/mobile/map.html
   NCI Breast Cancer Risk Assessment Tool for Mobile
       http://www.cancer.gov/bcrisktoolmobile/
   NLM Medline Plus Mobile
       http://m.medlineplus.gov/
Point-of-Care Diagnostics Tools
          (Examples)
A Wearable Chemical Sensor System
    for Personal Exposure Assessment

                                    http://www.airnow.gov




    Selective detection of VOCs
    (hydrocarbon and acid vapors)
   Sensitive: ppb – ppm
   Real-time: sec. – min.
   Spatially resolved
   Wearable: cell phone size
                                             Nongjian Tao, Arizona State University
   Cell phone based interface
LUCAS
  microscope                    Lens-free microscope (LUCAS)
                                for surveillance and diagnosis of
                                infectious diseases in resource-
                                limited settings




                                     Cell phone transmits      Computer software
                                     image                     automatically
                                                               interprets images at
                                                               remote site

LUCAS images of CD4+ and CD8+ T cells        Photos from Karin Nielsen and Aydogan Ozcan
compared to a regular microscope image..                                Karin Nielsen, UCLA
                                                          multidisciplinary training program
Real-time Adherence Monitoring
for HIV Antiretroviral Therapy in Uganda
David Bangsberg, Massachusetts General Hospital




                                             Est. probability of viral control




                                                                                 Parienti, et al. 2008
Future Directions
Important questions remain

   Defining mHealth: How do we reach consensus?
   How do we scale up promising pilot studies?
   CER: what do we compare mHealth against?
   How do we optimize both innovation and safety?
   What are the business models for sustainability?
   What roles should the government play?
   What is mechanisms are best for funding mHealth
    initiatives?
      Grants/Contracts
      SBIR/STTR
      Challenges
Other important issues for future
              mHealth development
   FDA – Regulation of mobile medical applications
        Guidance (draft):
         http://www.fda.gov/medicaldevices/productsandmedicalprocedures/
         ucm255978.htm
   HIPAA
        Proposed changes:
         http://www.hhs.gov/news/press/2011pres/05/20110531c.html
   Consumer Privacy & Security requirements:
        FTC: http://business.ftc.gov/privacy-and-security
   Section 508 compliance
        508 refresh (draft): http://www.access-board.gov/sec508/update-
         index.htm
HHS mHealth Groups – Get Involved!

   HHS mHealth Community of Practice
        https://list.nih.gov/cgi-bin/wa.exe?SUBED1=HHS_MHEALTH_COP


   NIH mHealth Inter-Institute Interest Group
   SAMHSA Mobile Working Group
   HRSA ‘text4baby’ Evaluation Technical Advisory Group

   Wireless Medical Technologies Working Group (led by NIBIB)
   Federal mHealth Collaborative (led by ONC & HRSA)
   Cross-Agency Telehealth Work Group
   Mobile-Gov Community of Practice (led by GSA)
THANK YOU

Audie A. Atienza, PhD
 Audie.Atienza@HHS.Gov

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Mobile Health: Highlights and Future Directions

  • 1. Mobile Health: Highlights and Future Directions Audie A. Atienza, PhD Senior Health Technology Advisor Department of Health and Human Services Office of the Secretary Behavior Scientist National Cancer Institute National Institutes of Health October 2011 HHS New Media Webinar Series
  • 2. Before there were cell phones, there was…
  • 3. Who was the real hero in Star Wars? Built-In Sensor for Environmental Scan Talk with other computer systems and optimize performance Store and communicate critical information
  • 4.
  • 5. The Tale of 2 Apps  Electric street lamp: “Electricity is not in any sense a necessity, and under no conditions is it universally used by the people of a community. It is but a luxury enjoyed by a small proportion of the members of any municipality, and yet if the plant be owned and operated by the city, the burden of such ownership and operation must be borne by all the people through taxation. Now, electric light is not a necessity for every member of the community. It is not the business of any one to see that I use electricity, or gas, or oil in my house, or even that I use any form of artificial light at all.” (Oct. 24, 1905, Richmond, Virginia, Times-Dispatch, by Henry Anderson). http://publicola.com/2009/12/11/the-killer-app-of-1900-2/  Ringtones: “Ringtones were super-hot in the middle of last decade, as everyone started to get cellphones, and have since fallen in popularity.” http://www.businessinsider.com/chart-of-the-day-remember-ringtones-2010-12
  • 6. The Mobile Revolution Mobile technology is everywhere!!!
  • 7. “The trend is indisputable: Broadcast television viewership is declining, and it has been for the past two decades. But since the birth of the iPhone and the Android operating system, mobile data use has exploded. By 2015 traffic will be some 20 times its 2010 level.” --Sources: FCC, Spectrumwiki, Nielsen, CTIA, National Association of Broadcasters, Cisco, Rysavy Research Fortune Magazine, July 27, 2011 http://tech.fortune.cnn.com/2011/07/27/spectrum-squeeze-battle-for-bandwidth/
  • 12.
  • 13. http://www.pewinternet.org/~/media/Files/Reports/ 2010/PIP_Mobile_Health_2010.pdf “…57% of American adults have a wireless connection and use a laptop or a cell phone to access the internet…78% of wireless internet users have looked online for health information…”
  • 16.
  • 19. 50+ Case Studies Described http://www.unfoundation.org/global-issues/technology/mhealth-report.html
  • 21. Remember 2007… June 2007, first iPhones released October 2008, first Android phone released In less than 5 years, iPhones and Android phones have become prolific
  • 22. 2009: 1.5 Trillion Text Messages Sent in US 4.1 billion SMS messages sent daily Game Changer! Consumer Centered & Driven Change
  • 24.
  • 25. Definitions – Helpful???  mHealth: Using mobile communications—such as PDAs and mobile phones—for health services and information (UN Foundation; http://www.unfoundation.org/global-issues/technology/mhealth-report.html)  mHealth stands for mobile-based or mobile-enhanced health solutions, or the idea that global wireless networks and mobile devices (cellphones, smartphones, mobile-enabled diagnostic devices) are powerful vehicles for delivering innovative medical and health services to the farthest reaches of the globe (mHealth Alliance, http://www.mhealthalliance.org/about/frequently-asked-questions)  mHealth: emerging mobile communications and network technologies for healthcare (Istepanian et al. 2005)  (Mobile-HEALTH) An umbrella term for wireless devices that are used in healthcare. It includes mobile monitors worn by patients as well as smartphones that physicians and nurses use to obtain and disseminate information. (PC Magazine; http://www.pcmag.com/encyclopedia_term/0,2542,t=mHealth&i=61665,00.asp)  Mobile health decouples time and space to assure the best state of health for the individual and the population (Group 4AM Session; http://www.scribd.com) No consensus!!
  • 26. Eric Dishman on mHealth Concepts like "home health" and "wireless" and "smart phone" and "telehealth" are being bandied about as if they are all the same thing, under the rubric of "mHealth," without much distinction between these very different capabilities, value propositions, and markets. Methinks we doth proclaim too much! I am becoming worried that we don't really know what each other is talking about when we say "mHealth." If "mHealth" is all of these things and more....if "mHealth" is everything...then it is nothing. The phrase has become so slippery, so ubiquitous as to become almost useless. We must be more careful in defining and aligning what we're talking about, and I encourage these various workshops and organizers to spend some time clarifying and specifying what's at play here. http://blogs.intel.com/healthcare/2010/08/the_hype_and_hope_of_mhealth.php
  • 27. The critical aspects of mobile health is the use of MOBILE technology “not all mobile health is wireless” and “not all wireless health is mobile”. Don Jones, Vice President, Business Development, Health & Life Sciences at Qualcomm, http://mobihealthnews.com/8997/2010-operators-payers-finally-interested-in-mhealth/
  • 28. mHealth tools include:  Health Text Messaging (feature & smart phones)  Smart Phone Apps/ Tablet Apps  Native App, Web-Based App, vs. Hybrid App  Mobile Web  Ambulatory Monitoring  Heart Rate, Blood Pressure, GSR, Glucose  Motion Sensors  Pedometers, Accelerometers, Gyroscopes  Body Area Networks  Global Positioning Systems  Portable Point of Care Diagnostic Devices  Mobile Games for Health
  • 30. HHS Text4Health Task Force formed in November 2010 See - http://www.hhs.gov/open/initiatives/mhealth/recommendations.html
  • 31. Health Text Messaging (examples)  CDC Mobile Tips & Alerts  http://www.cdc.gov/mobile/  CDC NHANES Text Message Pilot  NCI SmokeFreeTxt  http://smokefree.gov/smokefreetxt/  NIH funded research  e.g., mDiet (PI: Kevin Patrick)  ‘text4baby’ program  http://www.text4baby.org
  • 32. HHS Mobile Apps (examples)  AHRQ Electronic Preventive Services Selector-ePSS  http://itunes.apple.com/us/app/ahrq-epss/id311852560?mt=8  HRSA Find a Health Clinic  http://www.hrsa.gov/about/mobile/  NICHD/NLM - Embryo  http://itunes.apple.com/app/embryo/id422337604  NIH - My Dietary Supplements (MyDS)  http://ods.od.nih.gov/about/mobile/aboutmyds.aspx  NLM Mobile Apps  http://www.nlm.nih.gov/mobile/  SAMHSA Treatment Locator  http://apps.usa.gov/samhsa-treatment-locator/
  • 33. HHS Mobile Web (examples)  AIDS.gov Mobile  http://m.aids.gov/  CDC Mobile - Hurricane Recovery  http://www.bt.cdc.gov/mobile.asp  HRSA Find a Health Clinic  http://www.hrsa.gov/mobile/map.html  NCI Breast Cancer Risk Assessment Tool for Mobile  http://www.cancer.gov/bcrisktoolmobile/  NLM Medline Plus Mobile  http://m.medlineplus.gov/
  • 35. A Wearable Chemical Sensor System for Personal Exposure Assessment http://www.airnow.gov  Selective detection of VOCs (hydrocarbon and acid vapors)  Sensitive: ppb – ppm  Real-time: sec. – min.  Spatially resolved  Wearable: cell phone size Nongjian Tao, Arizona State University  Cell phone based interface
  • 36. LUCAS microscope Lens-free microscope (LUCAS) for surveillance and diagnosis of infectious diseases in resource- limited settings Cell phone transmits Computer software image automatically interprets images at remote site LUCAS images of CD4+ and CD8+ T cells Photos from Karin Nielsen and Aydogan Ozcan compared to a regular microscope image.. Karin Nielsen, UCLA multidisciplinary training program
  • 37. Real-time Adherence Monitoring for HIV Antiretroviral Therapy in Uganda David Bangsberg, Massachusetts General Hospital Est. probability of viral control Parienti, et al. 2008
  • 39. Important questions remain  Defining mHealth: How do we reach consensus?  How do we scale up promising pilot studies?  CER: what do we compare mHealth against?  How do we optimize both innovation and safety?  What are the business models for sustainability?  What roles should the government play?  What is mechanisms are best for funding mHealth initiatives?  Grants/Contracts  SBIR/STTR  Challenges
  • 40.
  • 41. Other important issues for future mHealth development  FDA – Regulation of mobile medical applications  Guidance (draft): http://www.fda.gov/medicaldevices/productsandmedicalprocedures/ ucm255978.htm  HIPAA  Proposed changes: http://www.hhs.gov/news/press/2011pres/05/20110531c.html  Consumer Privacy & Security requirements:  FTC: http://business.ftc.gov/privacy-and-security  Section 508 compliance  508 refresh (draft): http://www.access-board.gov/sec508/update- index.htm
  • 42. HHS mHealth Groups – Get Involved!  HHS mHealth Community of Practice  https://list.nih.gov/cgi-bin/wa.exe?SUBED1=HHS_MHEALTH_COP  NIH mHealth Inter-Institute Interest Group  SAMHSA Mobile Working Group  HRSA ‘text4baby’ Evaluation Technical Advisory Group  Wireless Medical Technologies Working Group (led by NIBIB)  Federal mHealth Collaborative (led by ONC & HRSA)  Cross-Agency Telehealth Work Group  Mobile-Gov Community of Practice (led by GSA)
  • 43. THANK YOU Audie A. Atienza, PhD Audie.Atienza@HHS.Gov