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Structural formulas of 20 amino acids common in proteins

                                 _
                           COO
                       +                                          Non-polar groups
    Glycine      H3N       CH         H
    Gly
    G
                                 _
                           COO
                       +
    Alanine      H3N       CH         CH3
    Ala
    A
                                 _
                           COO        CH3
                       +
    Valine       H3N       CH         CH    CH3
    Val
    V
                                 _
                           COO                  CH3
                       +
    Leucine      H3N       CH         CH2       CH    CH3
    Leu
    L
                                 _
                           COO        CH3
                       +
    Isoleucine   H3N       CH         CH    CH2       CH3
    Ile
    I
                                 _
                           COO
                                      CH2
    Proline                      CH
                                          CH2
    Pro
                                HN
    P                                 CH2

                                 _
                           COO
                       +
                                                                  Groups with S
    Cysteine     H3N       CH         CH2       SH
    Cys
    C
                                 _
                           COO
                       +
    Methionine   H3N       CH         CH2       CH2   S     CH3
    Met
    M
                                 _
                           COO
                       +
                                                                  Polar OH groups
    Serine       H3N       CH         CH2       OH
    Ser
    S

                                 _
                           COO        OH
                       +
    Threonine    H3N       CH         CH    CH3
    Thr
    T



By Israel Hanukoglu, Ph.D. http://www.science.co.il/Biomedical/Molecules/Amino-Acids/
_
                               COO                 O
                          +
                                                                                                Polar amide groups
    Asparagine      H3N        CH            CH2   C       NH2
    Asn
    N

                                        _
                               COO                             O
                          +
    Glutamine       H3N        CH            CH2   CH2         C       NH2
    Gln
    Q

                                        _
                               COO                 O
                                                                                                Charged (−), acidic
                          +                                          +
    Aspartic acid   H3N        CH            CH2   C       O       H
    Asp
    D

                                        _
                               COO                             O
                          +                                                   +
    Glutamic acid   H3N        CH            CH2   CH2         C       O H
    Glu
    E
                                        _
                               COO
                                                           NH
                                                                                                Charged (+), basic
                          +
    Histidine       H3N        CH            CH2
    His                                                N
    H
                                        _
                               COO
                          +                                                           +
    Lysine          H3N        CH            CH2   CH2         CH2       CH2      NH3
    Lys
    K
                                        _                                             +
                               COO                                                NH2
                          +
    Arginine        H3N        CH            CH2   CH2         CH2       NH       C       NH2
    Arg
    R

                                    _
                              COO
                     +                                                                          Aromatic groups
    Phenylalanine H3N         CH            CH2
    Phe
    F

                                        _
                               COO
                          +
    Tyrosine        H3N        CH            CH2                         OH
    Tyr
    Y

                                        _
                               COO
                          +
    Tryptophan      H3N        CH            CH2
    Trp                                                    NH
    W




By Israel Hanukoglu, Ph.D. http://www.science.co.il/Biomedical/Molecules/Amino-Acids/

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Amino acid-formulas

  • 1. Structural formulas of 20 amino acids common in proteins _ COO + Non-polar groups Glycine H3N CH H Gly G _ COO + Alanine H3N CH CH3 Ala A _ COO CH3 + Valine H3N CH CH CH3 Val V _ COO CH3 + Leucine H3N CH CH2 CH CH3 Leu L _ COO CH3 + Isoleucine H3N CH CH CH2 CH3 Ile I _ COO CH2 Proline CH CH2 Pro HN P CH2 _ COO + Groups with S Cysteine H3N CH CH2 SH Cys C _ COO + Methionine H3N CH CH2 CH2 S CH3 Met M _ COO + Polar OH groups Serine H3N CH CH2 OH Ser S _ COO OH + Threonine H3N CH CH CH3 Thr T By Israel Hanukoglu, Ph.D. http://www.science.co.il/Biomedical/Molecules/Amino-Acids/
  • 2. _ COO O + Polar amide groups Asparagine H3N CH CH2 C NH2 Asn N _ COO O + Glutamine H3N CH CH2 CH2 C NH2 Gln Q _ COO O Charged (−), acidic + + Aspartic acid H3N CH CH2 C O H Asp D _ COO O + + Glutamic acid H3N CH CH2 CH2 C O H Glu E _ COO NH Charged (+), basic + Histidine H3N CH CH2 His N H _ COO + + Lysine H3N CH CH2 CH2 CH2 CH2 NH3 Lys K _ + COO NH2 + Arginine H3N CH CH2 CH2 CH2 NH C NH2 Arg R _ COO + Aromatic groups Phenylalanine H3N CH CH2 Phe F _ COO + Tyrosine H3N CH CH2 OH Tyr Y _ COO + Tryptophan H3N CH CH2 Trp NH W By Israel Hanukoglu, Ph.D. http://www.science.co.il/Biomedical/Molecules/Amino-Acids/