The annual Christmas Quiz for aspergillosis patients & carers held to win the David Macintyre Memorial Trophy

1. Support Meeting for
Aspergillosis Patients
LED BY GRAHAM ATHERTON
SUPPORTED BY
GEORGINA POWELL, DEBBIE KENNEDY & DEBORAH HAWKER
NAC CENTRE MANAGER CHRIS HARRIS
CHRISTMAS QUIZ
NATIONAL ASPERGILLOSIS CENTRE
UHSM
MANCHESTER
Fungal Research Trust

2. Christmas Quiz - People
1. What has Chris Hoy, Kylie and Centre Manager
Chris Harris got in common?
• They are on similar salaries?
• They all like ‘Spinning Around’?
• None of them can sing

3. Christmas Quiz - People
2. We all know who is the most senior, but who lives
the highest above sea level?
• Graham
• Prof Denning
• Georgina
• Debbie

4. Christmas Quiz - People
3. What is thought to be the derivation of the surname
‘Hawker’
• It is an occupational name for someone who breeds & trains
hawks (appropriately birds who commonly get aspergillosis)
• It is an occupational name for someone who sell goods in
street markets(peddler, costermonger)
• It is an occupational name for someone who plays American
football for the Altanta Hawks

5. Christmas Quiz - People
4. Debbie Kennedy is a distant relative of the famous
Kennedy family in the US?
• True
• False
• Maybe

6. Christmas Quiz - People
5. Graham’s family name is Clare (not Atherton).
Where is this name thought to originate from?
• County Clare, Ireland
• Richard fitz Gilbert ((de Clare) colleague of William the
Conquerer)
• Clare village, Suffolk

7. Christmas Quiz - History
6. Where was the first recorded description of an
invasive aspergillosis in an immunocompromised
patient made?
• California, USA
• Gloucester, UK
• Pasteur Institute, France

8. Christmas Quiz - History
7. When did the first recorded description of an
aspergilloma (fungal ball) take place?
• 1862
• 1905
• 1938

9. Christmas Quiz - History
8. In which year was the first patient treated with
voriconazole for aspergillosis and where?
• 1995, Manchester
• 1996, London
• 1997, Brussels

10. Christmas Quiz - History
9. When and to whom was the first known successful
operation on an aspergillosis patient?
• WWII, Downed fighter pilot
• 1898, Soldier in the Boer War
• 1790, Soldier of the French Revolution

11. Christmas Quiz - History
10. Prior to around 1900 fungi were thought to be
• Plants
• Animals
• Algae

12. Christmas Quiz - Talks
11. Creative writing. The group all contributed to a
poem that was written by Caroline Hawkridge and
distributed in the clinic, What was the poem about?
• Hospital
• Car park
• Contrasting experiences of doctors and patients

13. Christmas Quiz - Talks
12. Ann Haylett gave us a talk on photosensitivity.
What makes aspergillosis patients sensitive to the sun
• Aspergillus increases sensitivity to the sun
• Long term steroid treatment thins the skin
• Voriconazole can make us sensitive to sunshine

14. Christmas Quiz - Talks
13. Marie Kirwan gave us a talk on refining diagnostic
techniques for aspergillosis. She found that the RT-
PCR technique might have benefits – what were these?
• Non-invasive sampling
• Quick to get result
• Result seemed as accurate as more invasive
techniques
• All of the above

15. Christmas Quiz - Talks
14. William Kidd gave us a talk on the importance of
keeping damp from our homes by using adequate
ventilation. What did he say was the main contributor
to excess moisture in the air in the home?
• Cooking
• Bathing & showering
• Drying laundry on radiators
• Breathing

16. Christmas Quiz - Talks
15. Cheryl Pearse talked about strategies to stop
smoking. How many chemical were known to be in
cigarette smoke & how many were cancer causing?
• 100/1
• 1000/20
• 4000/70
• 9000/100

17. Christmas Quiz - Talks
16. Livingstone Chishimba held a Question & Answer
session in May. When considering whether or not to
give a patients a certain medication what did
Livingstone say was one of the most important
considerations?
• Risk/Benefit ratio must be weighed
• Age of the patient
• Quality of Life score

18. Christmas Quiz - Talks
17. Graham Atherton gave a talk on the latest advances
in research that might help aspergillosis patients. This
photo was shown, what is it?
 A biopsy showing Aspergillus growing
 Rat lung being regenerated using stem cells
 Human lungs being cleaned prior to transplant

19. Christmas Quiz - Talks
18. Dr Paul Bowyer (Senior lab scientist) told us about
the latest advances in research we are carrying out at
the National Aspergillosis Centre. He gave some great
news that we have a strong suggestion that all CPA and
ABPA patients do not express a particular gene. Was it
 a-lectin
 b-lectin
 c-lectin
 d-lectin

20. Christmas Quiz - Talks
19. Dr Libby Ratcliffe talked about aches & pains. Did
she have a survival manual to give us?
 Yes of course
 No it is a very complicated subject

21. Christmas Quiz - Talks
20. Malcolm Richardson talked about ‘Everyday
Moulds’. He mentioned an outbreak of fungal
meningitis in the US which is currently ongoing. Was
this caused by:
 Mouldy washing machine seals
 Construction work outside of hospitals
 Contaminated injectable steroid solution
 Compost heaps

22. Christmas Quiz - Aspergillosis
21. What is thought to be a major source of aspergillus
spores in the home at Christmas?
 Christmas tree
 Christmas pudding
 Christmas crackers

23. Christmas Quiz - Aspergillosis
22. What is thought to possibly be a major source of
antifungal resistant aspergillus spores in our
environment?
We give out too many antifungals to patients
Damp homes produce resistant spores
Large scale use of azoles as pesticides by farmers

24. Christmas Quiz - Aspergillosis
23. Why is it important to look out for interactions
between medications?
We might be able to save money
Side effects could be worsened by interactions
Some drugs won’t dissolve properly if mixed
together

25. Christmas Quiz - Aspergillosis
24. Why do we have to regularly check your antifungal
levels using blood tests
It is the only way to know you are getting the right
dose
We get paid for doing them – the more the better
Our nurses need regular practice at taking blood

26. Christmas Quiz - Aspergillosis
25. What should you be doing over Christmas for your
health?
Eat plenty of turkey, sprouts & exercise
Afterwards put your feet up and watch TV
Keep warm and sleep well
All of these – its Christmas!
Celebrate the end of the world not happening today!

27. Answers

28. Christmas Quiz - People
1. What has Chris Hoy, Kylie and Centre Manager
Chris Harris got in common?
• They are on similar salaries?
• They all like ‘Spinning Around’?
• None of them can sing

29. Christmas Quiz - People
2. We all know who is the most senior, but who lives
the highest above sea level?
• Graham
• Prof Denning
• Georgina
• Debbie

30. Christmas Quiz - People
3. What is thought to be the derivation of the surname
‘Hawker’
• It is an occupational name for someone who breeds & trains
hawks (appropriately birds who commonly get aspergillosis)
• It is an occupational name for someone who sell goods in
street markets(peddler, costermonger)
• It is an occupational name for someone who plays American
football for the Altanta Hawks

31. Christmas Quiz - People
4. Debbie Kennedy is a distant relative of the famous
Kennedy family in the US?
• True
• False
• Maybe

32. Christmas Quiz - People
5. Graham’s family name is Clare (not Atherton).
Where is this name thought to originate from?
• County Clare, Ireland
• Richard fitz Gilbert ((de Clare) colleague of William the
Conquerer)
• Clare village, Suffolk

33. Christmas Quiz - History
6. Where was the first recorded description of an
invasive aspergillosis in an immunocompromised
patient made?
• California, USA
• Gloucester, UK (NE Rankin)
• Pasteur Institute, France

34. Christmas Quiz - History
7. When did the first recorded description of an
aspergilloma (fungal ball) take place?
• 1862
• 1905
• 1938

35. Christmas Quiz - History
8. In which year was the first patient treated with
voriconazole for aspergillosis and where?
• 1995, Manchester
• 1996, London
• 1997, Brussels

36. Christmas Quiz - History
9. When and to whom was the first known successful
operation on an aspergillosis patient?
• WWII, Downed fighter pilot
• 1898, Soldier in the Boer War
• 1790, Soldier of the French Revolution

37. Christmas Quiz - History
10. Prior to around 1900 fungi were thought to be
• Plants
• Animals
• Algae

38. Christmas Quiz - Talks
11. Creative writing. The group all contributed to a
poem that was written by Caroline Hawkridge and
distributed in the clinic, What was the poem about?
• Hospital
• Car park
• Contrasting experiences of doctors and patients

39. Christmas Quiz - Talks
12. Ann Haylett gave us a talk on photosensitivity.
What makes aspergillosis patients sensitive to the sun
• Aspergillus increases sensitivity to the sun
• Long term steroid treatment thins the skin
• Voriconazole can make us sensitive to sunshine

40. Christmas Quiz - Talks
13. Marie Kirwan gave us a talk on refining diagnostic
techniques for aspergillosis. She found that the RT-
PCR technique might have benefits – what were these?
• Non-invasive sampling
• Quick to get result
• Result seemed as accurate as more invasive
techniques
• All of the above

41. Christmas Quiz - Talks
14. William Kidd gave us a talk on the importance of
keeping damp from our homes by using adequate
ventilation. What did he say was the main contributor
to excess moisture in the air in the home?
• Cooking
• Bathing & showering
• Drying laundry on radiators
• Breathing

42. Christmas Quiz - Talks
15. Cheryl Pearse talked about strategies to stop
smoking. How many chemical were known to be in
cigarette smoke & how many were cancer causing?
• 100/1
• 1000/20
• 4000/70
• 9000/100

43. Christmas Quiz - Talks
16. Livingstone Chishimba held a Question & Answer
session in May. When considering whether or not to
give a patients a certain medication what did
Livingstone say was one of the most important
considerations?
• Risk/Benefit ratio must be weighed
• Age of the patient
• Quality of Life score

44. Christmas Quiz - Talks
17. Graham Atherton gave a talk on the latest advances
in research that might help aspergillosis patients. This
photo was shown, what is it?
1. A biopsy showing Aspergillus growing
2. Rat lung being regenerated using stem cells
3. Human lungs being cleaned prior to transplant

45. Christmas Quiz - Talks
18. Dr Paul Bowyer (Senior lab scientist) told us about
the latest advances in research we are carrying out at
the National Aspergillosis Centre. He gave some great
news that we have a strong suggestion that all CPA and
ABPA patients do not express a particular gene. Was it
 a-lectin
 b-lectin
 c-lectin
 d-lectin

46. Christmas Quiz - Talks
19. Dr Libby Ratcliffe talked about aches & pains. Did
she have a survival manual to give us?
 Yes of course
 No it is a very complicated subject

47. Christmas Quiz - Talks
20. Malcolm Richardson talked about ‘Everyday
Moulds’. He mentioned an outbreak of fungal
meningitis in the US which is currently ongoing. Was
this caused by:
 Mouldy washing machine seals
 Construction work outside of hospitals
 Contaminated injectable steroid solution
 Compost heaps

48. Christmas Quiz - Aspergillosis
21. What is thought to be a major source of aspergillus
spores in the home at Christmas?
 Christmas tree
 Christmas pudding
 Christmas crackers

49. Christmas Quiz - Aspergillosis
22. What is thought to possibly be a major source of
antifungal resistant aspergillus spores in our
environment?
We give out too many antifungals to patients
Damp homes produce resistant spores
Large scale use of azoles as pesticides by farmers

50. Christmas Quiz - Aspergillosis
23. Why is it important to look out for interactions
between medications?
We might be able to save money
Side effects could be worsened by interactions
Some drugs won’t dissolve properly if mixed
together

51. Christmas Quiz - Aspergillosis
24. Why do we have to regularly check your antifungal
levels using blood tests
It is the only way to know you are getting the right
dose
We get paid for doing them
Our nurses need regular practice at taking blood

52. Christmas Quiz - Aspergillosis
25. What should you be doing over Christmas for your
health?
Eat plenty of turkey, sprouts & exercise
Put your feet up and watch TV all day
Keep warm
All of these – its Christmas!

53. The Staff
Aspergi
you a
Christ

54. Thank You
“The best chance we have of beating this illness is to
work together”
Living with it, Working with it, Treating it
Fungal Infection Trust