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E-DES: 
Eindhoven Diabetes Education Simulator 
Anne Maas (anne.maas@mmc.nl) 
Carola van Pul1, Ward Cottaar2, Peter Hilbers2, Natal van Riel2, Harm Haak1. 
1 MĂĄxima Medical Center, Eindhoven. 
2 Eindhoven University of Technology, Eindhoven.
Diabetes 
Norris 2002 Diabetes Care 25:1159–1171, 2002
Current diabetes self-management education 
??? 
food 
insulin 
– 
stress 
+ 
physical activity 
– 
+ 
blood glucose level
Improve efficacy through eHealth solutions 
•More patients can benefit 
•Reduced costs 
•Opportunity to practice
883 diabetes apps for the iPhone alone… so why another one? 
•Most apps donot differentiatebetween T1DM and T2DM. 
•Focus on simple logging of blood glucoseinstead of self-management. 
•Only 20% give individualized feedback. 
•Consumer apps don’t giveevidence- based guidance. 
www.sugarpal.nl
Objective 
•Individualized simulator (game) 
•Predict glucose & insulin values over time 
•Type 1 and type 2 patients 
•Input: food, medication, exercise, stress, illness
Physiological model
Models for healthy people eating different 
meals 
0 60 120 180 240 300 360 
4 
5 
6 
7 
8 
time [min] 
G 
pl 
[mmol/L] 
0 60 120 180 240 300 360 
time [min] 
tuna sandwich and muffin 
D = 96g; GL = 59 
wholemeal wheat bread 
D = 50g; GL = 32 
basmati rice 
D = 50g; GL = 29 
corn pasta 
D = 50g; GL = 37 
cereal with milk and fruit 
D = 50g; GL = 33
Current work: validating the diabetes model 
•Currently gathering type 1 and type 2 data 
•84 patients, 47 timepoints, 180 mL blood 
•Type 2 divided in 6 classes
Next phase: user interface
Take home messages 
We are developing E-DES: 
•a scientifically validated educational simulator for patients with diabetes type 1 and 2 
•it models different meals and can be individualized 
•it distinguishes different groups of diabetes type 2 patients, rather than treating them as 1 
•it will become freely available 
We are still looking for partners to further develop the user interface!
•N van Riel 
•P Hilbers 
•W Cottaar 
•C van Pul 
•H Haak 
Sponsored by Novo Nordisk 
The team 
www.diabetessimulator.wordpress.com

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Games for Health - Anne Maas - E-DES: the Eindhoven Diabetes Education Simulator

  • 1. E-DES: Eindhoven Diabetes Education Simulator Anne Maas (anne.maas@mmc.nl) Carola van Pul1, Ward Cottaar2, Peter Hilbers2, Natal van Riel2, Harm Haak1. 1 MĂĄxima Medical Center, Eindhoven. 2 Eindhoven University of Technology, Eindhoven.
  • 2. Diabetes Norris 2002 Diabetes Care 25:1159–1171, 2002
  • 3. Current diabetes self-management education ??? food insulin – stress + physical activity – + blood glucose level
  • 4. Improve efficacy through eHealth solutions •More patients can benefit •Reduced costs •Opportunity to practice
  • 5. 883 diabetes apps for the iPhone alone… so why another one? •Most apps donot differentiatebetween T1DM and T2DM. •Focus on simple logging of blood glucoseinstead of self-management. •Only 20% give individualized feedback. •Consumer apps don’t giveevidence- based guidance. www.sugarpal.nl
  • 6. Objective •Individualized simulator (game) •Predict glucose & insulin values over time •Type 1 and type 2 patients •Input: food, medication, exercise, stress, illness
  • 8. Models for healthy people eating different meals 0 60 120 180 240 300 360 4 5 6 7 8 time [min] G pl [mmol/L] 0 60 120 180 240 300 360 time [min] tuna sandwich and muffin D = 96g; GL = 59 wholemeal wheat bread D = 50g; GL = 32 basmati rice D = 50g; GL = 29 corn pasta D = 50g; GL = 37 cereal with milk and fruit D = 50g; GL = 33
  • 9. Current work: validating the diabetes model •Currently gathering type 1 and type 2 data •84 patients, 47 timepoints, 180 mL blood •Type 2 divided in 6 classes
  • 10. Next phase: user interface
  • 11. Take home messages We are developing E-DES: •a scientifically validated educational simulator for patients with diabetes type 1 and 2 •it models different meals and can be individualized •it distinguishes different groups of diabetes type 2 patients, rather than treating them as 1 •it will become freely available We are still looking for partners to further develop the user interface!
  • 12. •N van Riel •P Hilbers •W Cottaar •C van Pul •H Haak Sponsored by Novo Nordisk The team www.diabetessimulator.wordpress.com