Cell Signaling

Cell Signaling at the Cell Surface

Hydrophilic Signals ,[object Object],[object Object],[object Object],[object Object],[object Object]

Types of Signals ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

How do signaling molecules work? ,[object Object],[object Object],[object Object]

Classes of Receptors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Common Properties of Cell-Surface Receptors - I ,[object Object],[object Object],[object Object],[object Object]

Common Properties of Cell-Surface Receptors - II ,[object Object],[object Object],[object Object],[object Object]

Common Properties of Cell-Surface Receptors - III ,[object Object]

Second Messengers ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Role of Ca +2 ,[object Object],[object Object],[object Object],[object Object]

Other Proteins Involved in Signal-Transduction - I ,[object Object],[object Object],[object Object],[object Object],[object Object]

Classes of GTPase Switch Proteins ,[object Object],[object Object]

Other Proteins Involved in Signal-Transduction - II ,[object Object],[object Object],[object Object],[object Object]

Receptors and Associated Signal-Transduction Proteins may be Localized. ,[object Object],[object Object],[object Object]

Protein clustering in lipid rafts. Recall that lipid rafts are non-random association of lipids (typically cholesterol and sphingolipids) in the plasma membrane. Many signaling receptors and associated proteins are found in lipid rafts associated with caveolin protein. These rafts are called caveolae.

G-Protein Coupled Receptors that Activate/Inhibit Adenylyl Cyclase ,[object Object]

Structure of Trimeric G Protein ,[object Object],[object Object],[object Object]

Signal Amplification ,[object Object]

Activation of Adenylyl Cyclase ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

What does adenylyl cyclase do? ,[object Object],[object Object],[object Object]

Two general types of G-protein coupled receptors ,[object Object],[object Object],[object Object],[object Object]

Glycogen Metabolism ,[object Object],[object Object],[object Object],[object Object]

The Role of PKA in Glycogen Metabolism ,[object Object]

Muscarinic Acetylcholine Receptors in Heart Muscle ,[object Object],[object Object],[object Object],[object Object],[object Object]

G-Protein Associated Receptors that Activate Phospholipase C ,[object Object],[object Object],[object Object],[object Object],[object Object]

Ca +2 /Calmodulin Complex ,[object Object],[object Object]

Cell Signaling

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Cell Signaling