8. “A global response to a
global problem: the epidemic
of overnutrition.” WHO
It is estimated that by 2020 2/3rds of the global
burden of disease will be attributable to chronic
non-communicable diseases, most of them
strongly associated with diet. The nutrition
transition towards refined foods, foods of animal
origin, and increased fats plays a major role in
the current global epidemics of obesity, diabetes
and cardiovascular diseases, among other non-
communicable conditions. Sedentary lifestyles and the
use of tobacco are also significant risk factors. …….. A
concerted multi-sectoral approach, involving the use of
policy, education and trade mechanisms, is necessary
to address these matters.
13. “A global response to a
global problem: the epidemic
of overnutrition.” WHO
It is estimated that by 2020 2/3rds of the global
Diabetes Heart Disease
burden of disease will be attributable to chronic
non-communicable diseases, most of them
strongly associated with diet. The nutrition
transition towards refined foods, foods of animal
Obesity High Blood Pressure
origin, and increased fats plays a major role in
the current global epidemics of obesity, diabetes
and cardiovascular diseases, among other non-
communicable conditions. Sedentary lifestyles and the
High Cholesterol
use of tobacco are also significant risk factors. …….. A
concerted multi-sectoral approach, involving the use of
policy, education and trade mechanisms, is necessary
to address these matters.
29. Perspective
• We eat more
– Sugar, Salt, Fat, Meat, Dairy
– 1970-2006:
• ↑ 24.5 % C/day ≈
617K/day
• We get less then ideal Physical Activity
– 18.8% of adults achieved CDC reccs on
Exercise
– 10% of adults >65 y/o
44. “A global response to a global
problem: the epidemic of
overnutrition.” WHO
It is estimated that by 2020 2/3rds of the global burden
of disease will be attributable to chronic
……if…….Lifestyle is the
noncommunicable diseases, most of them strongly
Problem
associated with diet. The nutrition transition towards
refined foods, foods of animal origin, and increased fats
plays a major role in the current global epidemics of
obesity, diabetes and cardiovascular diseases, among
other noncommunicable conditions. Sedentary
What of tobacco are also significant
lifestyles and the use
is the answer……..?
risk factors. …….. A concerted multi-sectoral approach,
involving the use of policy, education and trade
mechanisms, is necessary to address these matters.
45. Surgery
Pharmaceuticals
Physical Modalities
Lifestyle Medicine
48. 50% ↓ in all-cause
and cause specific
mortality
12 year Cohort Study
1507 men 832 Women
Ages 70-90 years
Outcomes: 10 yr all cause mortality
4 Factors: Med. diet, Moderate EtOH, physical exercise
and non-smoking were ass. w ↓ in ACM
49. “Not only do persons with better health habits
survive longer, but in such persons, disability is
postponed and compressed into fewer years
at the end of life.”
Vita, AJ et al. NEJM 1998; 338:1035-1041
50. Finnish Diabetes Prevention Trial
Total 522: 172M 350W
Av. age 55
Risk of
Av. BMI 31
Randomized to standard of care or
individualized lifestyle counseling
Diabetes ↓ 58 %
Av. f/u 3.2 yrs
(P<0.001)
“The reduction in the incidence of diabetes was
directly associated with changesN in lifestyle”
Engl J Med 2001;344:1343-50
51. Healthy living is the best revenge: findings from
the European Prospective Investigation Into
Cancer and Nutrition-Potsdam study 2009
• 23,153 participants (35 to 65yr) for about 8 years
• Rates of type 2 diabetes mellitus, myocardial
Sign Me Up!
infarction,all 4 factors at baseline you had
If you had stroke, and cancer
• • 4 Variables: of developing a chronic disease
78% lower risk
– Never smoking •
– BMI<30 lower risk of diabetes
• 93%
– •3.5 h/wk orrisk of myocardial infarction
81% lower more of physical activity
•50% lower risk of stroke, and
– healthy dietary principles (high intake of fruits,
•36% lower risk of cancer
vegetables, and whole-grain bread and low meat
consumption).
52. Motorola
• Cost ≈ $6 mil/yr on wellness and work/life programs
• Offerings: Health Screenings, Education, gym access
etc
• Cost-effectiveness:
– $1 invested in wellness benefits, $3.93 saved
– 2.4% increase in annual health care costs for
participating employees vs 18% increase for non-
participants
– $6.5 million annual savings in medical expenses for
lifestyle-related diagnoses (e.g., obesity,
hypertension, stress) compared with non-participants
53. Northeast Utilities
• 17% healthcare costs = LR
• WellAware program: financial incentives for participation, employees
and spouses eligible, a health risk assessment, secondary coronary
artery disease management program, phone contact and Internet site
allows access at work and home, and a toll free hotline for materials
and questions.
• 1st 2 years: 1.6 return on investment, including a $1,400,000 reduction
in lifestyle and behavioral claims and flat per capita costs for health
care.
• Participants demonstrated: 31% decrease in smoking, a 29% decrease
in lack of exercise, a 16% decrease in mental health risk, a 11%
decrease in cholesterol risk, an 10% improvement in eating habits, and
a 5% decrease in stress.
58. Exercise and Physical Health
• Reduces risk of
– Heart Disease ≈ 40%
– Obesity: ≈ 30-100%
– Stroke ≈ 50%
– Type 2 Diabetes ≈ 50%
– Hypertension ≈ 50%
– Disability delayed ≈15 years
– Colon Cancer ≈ 25-40%
– Breast Cancer ≈ 20%-44%
– Osteoporosis ≈ 20+%
• As many as 250,000 deaths per year in the United States
are attributable to a lack of regular physical activity
59. Exercise and Mental Health
• Regular Exercise:
– Reduces risk/severity of:
• Depression
• Anxiety
• ADD/ADHD
• Alzheimers Dementia
– Improves:
• Mental Clarity, test scores, focus
60. Exercise and Emotional Health
• Regular Exercise:
– Increases Self Confidence
– Teaches skills to manage adversity
– Enhances Self Esteem
– Develops Discipline
– Encourages Goal setting and self awareness
61. Exercise means pink spandex, going to a
gym, sweating with a bunch of people I
don’t even know or like!
62.
63. Categories
• Leisure time Exercise: organized sports,
running, gym activities, rehabilitation etc.
• Lifestyle Exercise: activity incorporated into our
daily pattern of life
– eg: parking in the distant portion of the parking lot rather then the first
bumper, taking the stairs instead of the elevator etc.
64. Present Recommendations
• Cardiovascular:
– 150 minutes of moderate-intensity exercise per
week.
– 30-60 minutes of moderate-intensity exercise (five
days per week) or 20-60 minutes of vigorous-
intensity exercise (three days per week).
65. Present Recommendations
• Resistance Training:
– 2-3 days per week
– All major muscle groups
– 2-4 sets of each exercise
– 48 hours in between sessions
http://www.acsm.org/about-acsm/media-room/news-releases/2011/08/01/acsm-issues-new-
recommendations-on-quantity-and-quality-of-exercise
67. All Kinds
• People
• Programs
• Locations
• Products: Pedometers, Accelerometers etc
68. Intensity of Exercise
Talk Test:
-Easy: Can Talk and Sing
-Moderate: Can Talk but not sing
Maximal Heart Rate:
-Intense: Can’t age) or sing
220-Age or 206.9-(0.67x talk
Heart Rate Reserve (HRR):
Max. HR- Resting HR = HRR
Target HR=HRR x % intensity + HR @ rest
69. Nutrition
DIEt
• Up to 50% of Americans are on a Diet
Lifestyle
70. Nutrition
• Health Promoting Nutrition:
• Majority of Calories derived from Plant-Based
Sources
• Limited Calories from Refined Foods and
Foods of Animal Origins
74. Toxins
• Get em’ out
• Get help if you need it
• You can do it
• You deserve it
75. Basics
• Physical Activity:
– Achieve 150 min of aerobic exercise and 2
sessions of strength training per week
• Nutrition:
– Eat a high nutrient density program
– Limit/moderate lean meats, limit refined foods,
fat, sodium and cholesterol
• Eliminate Smoking and Limit Alcohol
Consumption
80. Break Out: 4 minutes
• Set YOURSELF a SMART Goal for 1 Lifestyle
Measure and share it with your neighbor!
• Specific Exercise
• Measureable Nutrition
Toxins
• Achievable Sleep
• Realistic Emotional
Poise(Stress)
• Timely
81. Conclusion
• Personal Choices are powerful Medicine
• Assess YOUR Health Today
• Identify your health goals
• Develop a support team
• Take charge of your health today!
82. Conclusion
You are the most powerful influence
in your health today, tomorrow and
for years to come!
-- Bull World Health Organ. 2002;80(12):952-8. Epub 2003 Jan 23. Chopra M et al
Approx. 1,300,000 new cases per year www.cdc.gov/.../mmwrhtml/ figures/m846qsf.gif www.ncbi.nlm.nih.gov/ bookshelf/picrender.fcgi.. http://www.ctahr.hawaii.edu/CS/blogs/sustainable_agriculture/cdc_logo(2).jpg
Modifiable behavioral risk factors are leading causes of mortality in the United States. (JAMA, 2000 Mokdad et al. CDC) www.cdc.gov/cancer/ breast/statistics/ http://www.cdc.gov/cancer/Prostate/publications/decisionguide/
Fox, Caroline. Et al. Trends in the Incidence of Type 2 Diabetes Mellitus: Circulation 2006:113;2914-2918.
http://health.ucsd.edu/news/images/DPP1.jpg
In 2005-2008 11% of adults 20 years of age or older had diabetes. In 2005-2008 the percentage of adults with dm increased with age from 4% of persons 20-44 to 27% of adults 65 years of age or older http://meps.ahrq.gov/mepsweb/ Medical Expenditure Panel survey
http://www.heart.org/idc/groups/heart-public/@wcm/@sop/@smd/documents/downloadable/ucm_319587.pdf The prevalence of hypertension (defined as high blood pressure or taking antihypertensive medication) increases with age. In 2005–2008, 33%–34% of men and women 45–54 years of age had hypertension, compared with 67% of men and 80% of women 75 years of age and over (Table 67).
http://care.diabetesjournals.org/content/early/2010/09/30/dc10-0879.full.pdf+html 2010 --AHA 2004 --States if you have 2 of characteristics =‘s 2 times risk of death from coronary heart dz, if you have 4 of these =‘s you have 3.5 times the risk? http://www.reuters.com/article/2010/10/15/us-metabolic-syndrome-idUSTRE69E5FL20101015
http://sas-origin.onstreammedia.com/origin/gallupinc/GallupSpaces/Production/Cms/POLL/yxirhsg6pe-ttjvtlo_uuq.gif These findings are based on 24 months of Gallup-Healthways Well-Being Index daily tracking data from 2009 through 2010, encompassing surveys with more than 650,000 U.S. adults, aged 18 and older. The resulting sample sizes for every age from 18 through 90 -- ranging from roughly 1,500 to 18,000 cases -- allow for age-specific analysis of the data.
Rates of obesity tripled in last 20 yrs in adolescents
Agouti = defect in alpha melanocyte stimulating hormone a secondary molecule increased by increasing leptin levels. Early nutrition can influence DNA methylation because mammalian one-carbon metabolism, which ultimately provides the methyl groups for all biological methylation reactions, is highly dependent on dietary methyl donors and cofactors.[ 21 ] For example, dietary methionine and choline are major sources of one-carbon units, and folic acid, vitamin B 12 , and pyridoxal phosphate are critical cofactors in methyl metabolism. The genome of the preimplantation mammalian embryo undergoes extensive demethylation, and appropriate patterns of cytosine methylation are re-established after implantation.[ 4 ] These DNA methylation patterns must then be maintained over many rounds of rapid cellular proliferation during fetal and early postnatal development. Availability of dietary methyl donors and cofactors during critical ontogenic periods therefore might influence DNA methylation patterns. [ 10 and 16 ] Hence, early methyl donor malnutrition (i.e., overnutrition or undernutrition) could effectively lead to premature “epigenetic aging,” [ 22 ] thereby contributing to an enhanced susceptibility to chronic disease in later life. Vitamin B12, choline, Vitamin B6
Gila Reservation Arizona Maycoba, Mexico
Nauru World’s smallest island country just 8.s sq miles 95% are overweight/obese and 50% have diabetes
Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project.
-- compression-of-morbidity hypothesis predicts that the age at the time of initial disability will increase more than the gain in longevity, resulting in fewer years of disability and a lower level of cumulative lifetime disability.
--FDDP (N Engl J Med 2001;344:1343-50.)
http://aspe.hhs.gov/health/prevention/
( Journal of the American Medical Association JAMA: 2000, Vol. 283. No. 22, pp. 2961-2967) http://www.news.harvard.edu/gazette/1999/10.21/diabetes.html http://www.reuters.com/article/healthNews/idUSTRE53E71N20090415?feedType=RSS&feedName=healthNews http://www.nature.com/bjc/index.html http://www.ncbi.nlm.nih.gov/pubmed/18599492?ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
In fact in studies regular exercise has been proven as effective as antidepressants and anxiolytics in controlling mild-moderate depression
Must be high enough to actually see gains Studies demonstrate must at least be at 40% of max to see increases in cardiovascular endurance….. Moderate intensity is 64-76% of HR max http://www.mehn.org.au/images/stories/mehn/Ex_RPE_Scale.jpg http://lh4.ggpht.com/_hbZ_aIisSu8/Sj4dT9_2kPI/AAAAAAAAAbo/r-Hmqox_oJs/Table_thumb.jpg http://www.cvtoolbox.com/cvtoolbox1/exercise/supports/Exercise_METS.gif
-- http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm -- Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ . 297 : 319–328. --The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT, 2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives. -- -- http://www.nhlbi.nih.gov/new/press/nov30a99.htm -- Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
-- http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm -- Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ . 297 : 319–328. --The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT, 2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives. -- -- http://www.nhlbi.nih.gov/new/press/nov30a99.htm -- Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
-- http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm -- Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ . 297 : 319–328. --The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT, 2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives. -- -- http://www.nhlbi.nih.gov/new/press/nov30a99.htm -- Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
-- http://www.cdc.gov/nccdphp/publications/factsheets/Prevention/obesity.htm --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.nhlbi.nih.gov/health/prof/heart/hbp/salt_upd.pdf --http://www.usatoday.com/news/health/2008-02-10-salt-dangers_N.htm -- Intersalt Cooperative Research Group (1988). Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ . 297 : 319–328. --The contradictory nature of these findings accords with the unreliability of the methods used in NHANES III and IV (ie, 24-h dietary recall). Twenty-four-hour urinary sodium from complete urine samples is the only accurate way to estimate dietary salt intake, and this was not measured in NHANES III and IV. The large international study—INTERSALT, 2 which had 24-h urinary sodium and BP measured, showed that salt intake is directly associated with BP and the increase in BP with age in more than 10,000 individuals including both hypertensives and normotensives. -- -- http://www.nhlbi.nih.gov/new/press/nov30a99.htm -- Healthy adults living in a temperate climate can maintain a normal sodium balance with as little as 115 mg of dietary sodium per day. In consideration of the wide variation in Americans’ physical activity and climatic exposure, a safe minimum of 500 mg of sodium per day has been recommended.
SpecificWell definedClear to anyone that has a basic knowledge of the project MeasurableKnow if the goal is obtainable and how far away completion is Know when it has been achievedAgreed UponAgreement with all the stakeholders what the goals should be RealisticWithin the availability of resources, knowledge and time Time BasedEnough time to achieve the goalNot too much time, which can affect project performance