The study examined the effectiveness of treating dermal burn wounds under wound covers to maintain a moist environment. Patients with 5-30% total body surface area burns were divided into a study group that used hydrogel coatings and film dressings (n=60), and a control group that used dry bandages (n=35). The moist environment promoted removal of necrotic tissue, reduced bacterial contamination from 104 to 102-103 CFU/g, and shifted the wound healing process from degenerative to regenerative phases more quickly compared to the control group. Maintaining a moist wound environment through closed dressings is an effective way to positively influence wound healing without increasing endogenous intoxication.

1. WOUND COVERAGE IN PATIENTS
WITH DERMAL BURNS
Kovalenko O.M., Kovalenko A.O., Osadcha O.I.
Aim: to study effectiveness of treatment dermal burn wounds
under the covers.
Methods: 95 patients with superficial dermal burn 5-30% TBSA
aged 5-55 years were examined during 2009-2013. 60 patients
were selected for study group. Their wounds were treated
under wound covers in humid environment (hydrogel coating,
spongy polyurethane, film coating). The control group consisted
of 35 patients. Treatment of them wounds was conducted with
wet antiseptic solution bandages or hyperosmolar antibacterial
ointments.
Were used the clinical, immunological, cytological and
bacteriological methods of research.
National Medical University by O.O.Bogomolets,
Ukraine, Kyiv
EP386Acute Wounds
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2. Hydrocolloid, sponge dressings allows removing dermal
necrosis in a large area due to the active sorption wound
allocation. Bacteriological control showed high antibacterial
activity in the study group to pathogenic bacteria. Level
bacterial contamination of wounds patients study group
decreased from 104
CFU/g to 102
-103
CFU/g.
National Medical University by O.O.Bogomolets,
Ukraine, Kyiv
2

3. Indicators cytolytic activity of serum and
its fractions in patients with burn wounds
in a wet environment on 8-10 days after injury
Most of the surface of the necrotic tissue was removed and
melted with hydrogel coating after 7 days of dressing. Autolizys
superficial necrosis occurred in wounds in a wet environment.
National Medical University by O.O.Bogomolets,
Ukraine, Kyiv
3
Cytolytic activity of blood serum decreased by 15%, and performance
albumin fraction by 18%. It reduces the level of endogenous intoxication.

4. Changes of inflammatory response wounds
in a wet environment
Type of
inflammatory
reaction
Time after injury
3-5 day 7-9 day 13-15 day 17-21 day
main
group
compar.
group
main
group
compar.
group
main
group
compar.
group
main
group
compar.
group
Degenerative-
inflammatory
11,11% 58,82% – 17,64% – 11,76% – –
Inflammatory 38,89% 41,18% 11,11% 58,84% – 29,42% _ 5,88%
Inflammatory-
regenerative
44,44% – 22,22% 11,76% 11,11% 41,17% 5,56% 41,18%
Regenerative 5,56% – 66,66% 11,76% 88,89% 17,65% 94,44% 52,94%
66,66
44,44
Cytological studies has shown quick changing phases of wound
healing in patients of basic group took place. Degenerative and
degenerative-inflammatory types of wound healing have changed
rapidly in the most favourable inflammatory and regenerative-
inflammatory type.
88,89
National Medical University by O.O.Bogomolets,
Ukraine, Kyiv
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5. Conclusion:
1. Wound cover that keep the wound moist is
an effective way to influence the wound
process, which may be adjusted.
2. Maintain a moist wound in a closed chamber
changes the qualitative and quantitative
composition of microflora of wounds, reduces
microbial contamination of burn wounds,
prevents re-infection, replaces strains
pathogenic to opportunistic.
3. Moist environment for wound does not
enhances the level of endogenous intoxication,
but rather improves the course of burn disease.
National Medical University by O.O.Bogomolets,
Ukraine, Kyiv
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