2. Facts
⢠Ancestral origin developed as animals left sea
⢠Active starting from fetal age âweek 4â
⢠Secreting at fetal age âweek 18â
⢠Responsible for packaging iodide and
transporting it into the cell
⢠Also houses parafollicular cells (calcitonin)
⢠Shields the parathyroid gland (parathormone)
13. Long term Subclinical Hypo
⢠Social withdrawal
⢠Psychological labeling
⢠Withdrawal from western medicine (+)
⢠Small % go onto Hypo
14. Imbalances in a nutshell
⢠T4 (thyroxine)
⢠T3 (triiodothyronin)
⢠TSH (thyroid stimulating hormone)
15. T4
⢠The cool molecule created by land animals to
carry iodide throughout the blood and deliver
to the cell-most attached to TBG
⢠Most thyroxine is bound (but free is included
in the total)
⢠Free is âactiveâ can be calculated
(FreeThyroxineIndex)
⢠Free T4 (0.9-1.8ng/dL)
16. T3
⢠Less in amount but also attached to TBG
⢠Seems to have greater effect on the way the
body utilizes energy
⢠Better to get free T3 (240-450pg/dL)
17. Exogenous hormone
⢠Levothyroxine sodium (levothyroid, levoxyl, synthroid)
⢠Dessicated thyroid (armour/nature thyroid)
⢠Armour=corn fed/Nature=grass fed)
⢠Compounded Armour
⢠Liothyroinine sodium (cytomel)
⢠Liotrix (thyrolar)
⢠Compounded Liotrix
⢠The New England Journal of Medicine 1999;340:424-429, 469-470
18. TSH
⢠Hormone secreted by the pituitary gland
⢠Increase means brain thinks thyroid slow
⢠Decrease means brain thinks thyroid fast
⢠Supersensitive TSH (1-1.5mIU/L)
⢠THR (thyroid releasing hormone for pituitary
loop function)
19. Thyroid antibodies
⢠Thyroid peroxidase antibody
⢠Antithyroglobulin antibodies
⢠Problem: what is causing the antibodies to
attack?
⢠Further investigation (Naturopathy)
21. Iodine
⢠Supplanted by the government in salt, and in
some countries flour and cooking oil
⢠Potassium iodide created after dash diet
⢠Lack of can cause goiter or low production
thyroid
⢠Poor nutrition bringing back low iodine
⢠Chlorine, florine, bromine compete