The Cochrane Collaboration Colloquium: Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews

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Claire Glenton speaking at the XIV Cochrane Colloquium in Dublin, Ireland

Gesundheit & Medizin Technologie

Plenary 1 Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews Claire Glenton Pembroke

Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews Claire Glenton, Nordic Cochrane Centre, Norwegian branch/ Norwegian Knowledge Centre for the Health Services

Past achievements, future challenges ,[object Object],[object Object],[object Object]

Improving access by summarising results ,[object Object],[object Object],[object Object],[object Object],[object Object]

The Cochrane Collaboration can improve understanding and avoid the possibility of misrepresentation.. ,[object Object],[object Object],[object Object],[object Object]

Experiences when summarising Cochrane reviews ,[object Object],[object Object],[object Object],[object Object],[object Object]

We have tried to extract and consistently present what the reviews say about: ,[object Object],[object Object],[object Object]

Challenges we faced when trying to answer these questions ,[object Object],[object Object],[object Object]

Challenges 1. Missing information about important outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object],1 Vist 2003

Challenges 2. Continuous outcomes often difficult to interpret ,[object Object],[object Object],[object Object],1 Kho, Glenton, Pennick, Koy, Underland, Vist, Oxman, 2003

Challenges 3. Effect presented in different ways Risk difference Odds ratio Numbers Needed to Treat Qualitative presentations Relative risk reduction Relative risk improvement Weighted Mean Difference Percentages Standard mean difference Risk ratio

Challenges 3 . Quality of evidence evaluated in different ways ,[object Object],[object Object],[object Object],1 Vist 2003 2 Kho, Glenton, Pennick, Koy, Underland, Vist, Oxman, 2003

[object Object],[object Object],[object Object],How can we give a precise, consistent and understandable presentation of: ?

Solution: Summary of Findings Tables (SoF)

SoF Tables Focus on important outcomes only ,[object Object],[object Object],[object Object]

SoF Tables Present effect consistently ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

SoF Tables Continuous outcomes still a challenge ,[object Object],[object Object],[object Object],[object Object],[object Object]

SoF Tables Present quality consistently ,[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],Improving accessibility to lay people

While statistics may be precise ,[object Object],[object Object],1 Moxey, O’Connell, McGettigan, Henry, 2003

Qualitative presentations not the solution ,[object Object],[object Object],[object Object],1 Allen, Smith, Thornton 2001 2 Wills, Holmes-Rovner, 2003

Event rates (“10 people out of 100”) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],1 Schünemann, Herrin, Vist, Oxman, Akl, 2003

Lay version of SoF Tables Event rates Standardised comments when data not statistically significant

Continuous outcomes: problems still remain ,[object Object]

Tables as a basis for Plain Language Summaries ,[object Object],[object Object],[object Object]

Future plans ,[object Object],[object Object]

Conclusion: All summaries involve judgement and can lead to loss of precision, but... ,[object Object]

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The Cochrane Collaboration Colloquium: Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews

1. Plenary 1 Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews Claire Glenton Pembroke

2. Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews Claire Glenton, Nordic Cochrane Centre, Norwegian branch/ Norwegian Knowledge Centre for the Health Services

10.

11. Challenges 3. Effect presented in different ways Risk difference Odds ratio Numbers Needed to Treat Qualitative presentations Relative risk reduction Relative risk improvement Weighted Mean Difference Percentages Standard mean difference Risk ratio

12.

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14. Solution: Summary of Findings Tables (SoF)

15.

16.

17.

18.

19.

20.

21.

22.

23. Lay version of SoF Tables Event rates Standardised comments when data not statistically significant

24.

25.

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The Cochrane Collaboration Colloquium: Summing up: challenges and possible solutions when summarising the findings of Cochrane reviews

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