The Cochrane Collaboration Colloquium: Evidence Based Child Health: a Cochrane review Journal - why and how?

Plenary 1
EvidenceBased Child
Health: A Cochrane Review
Journal – why and how?
Martin Offringa
and Terry Klassen
Pembroke

www.evidencebasedchildhealth.com

Why and How?
Martin Offringa, MD, PhD
CoEditorinChief

Why?
o To make child health evidence
easier to find, interpret and use
o To “add value” to current
Cochrane reviews
o To increase impact of Cochrane
evidence for children


How?
oOnline journal
oPublished quarterly by Wiley
oEditorial process coordinated
by Canadian and Dutch
editorial offices


Editorial Board
o Virginia Moyer, Texas, USA
o Leontien Kremer, Amsterdam, NL
o Joan Robinson, Edmonton, Canada
o Jonathan Craig, Sydney, Australia
o Kent Stobart, Edmonton, Canada
o Lorne Becker, New York, USA
o Michael Smith, Craigavon, Northern Ireland

o Terry Klassen, Edmonton, Canada
o Martin Offringa, Amsterdam, NL


Two who make it really happen
o Denise Thomson, Edmonton, Canada
o Elvira van Dalen, Amsterdam, NL


How? (cont…)
o Each issue:
n 46 Cochrane reviews, reprinted in full
o Expert commentary
o Table of key findings
o Summary
n Umbrella Review
n Tips and Tricks
n Editors’ Introduction


Review reprinted in full

Summary

Expert commentary

Table of key findings


Cochrane review
o Reprinted in full so that readers have
the original source to which they can
refer
n HTML and PDF version
o Selected in an editorial process
n Relevance
n Quality
n Timeliness
n Fit


Journals Participating in the CSE Global Theme Issue on Poverty
and Human Development as of September 2006

Annals of African Medicine Nature Cell Biology
ATVB (Arteriosclerosis, Thrombosis, and Vascular Biology) Nature Genetics
BMJ Nature Immunology
Brazilian Journal of Medical and Biological Research Nature Materials
Breast Diseases: A Year Book Quarterly Nature Medicine
Canadian Pharmacists Journal Nature Methods
Circulation Nature Nanotechnology
Circulation Research Nature Physics
Clinics PLoS Biology
East African Medical Journal PLoS Clinical Trials
Environmental Health Perspectives PLoS Medicine
PNAS
Evidence Based Child Health *
Reviews of Modern Physics
Ghana Medical Journal
Science
Hypertension
Stroke
JAMA
The Lancet
Journal of Public Health Policy
Mountain Research and Development
Nature

EBCH Summary
o Aimed at health professionals
and consumers who wish a quick
overview of the review’s content
o Written by a writer at the Child
Health Field
o Peer reviewed by EB member

o example

EBCH Table of Key Findings
o Presents key outcomes of the review
o Decisions on relevant outcomes
o Statement on inference
n Building on work done by the CCA&RM
Group, GRADE, etc.

o example


Challenge: What to translate?
o ‘Demographics’
n Nr of RCTs, patients, contrasts?
n Quality SR?
n Quality RCTs?
o Contrasts, Outomes, and Subgroups
n Doses, routes, duration, delivered by whom?
n Clinical relevant, ELISAs, pain indexes?
n HQLQ trials?
o ‘Statistics’
n Patients ‘randomized’, or ‘analyzed’?
n Pooling heterogeneous material?
n Non pooled results?


Expert commentary
o To provide context for the
application of the evidence
presented by the review

o example

Umbrella Review
o Prepared according to the format of
the Cochrane Umbrella Reviews
Working Group
o Written on invitation

o example

Tips and Tricks
o Help readers interpret the
evidence, and use it correctly
o Written by EB members and lead
Cochrane ‘methodologist’


Editors’ Introduction
o Highlighting new developments
n in Child Health
n in Evidence Based Practice


Libraries EBCHoptin
Total

1000

800

600

400

200

0
March April May June July August


Geo split
Where?
France
2% 2% 3%
4%
28% Sweden
5%
Canada
10%
Australia
Japan
England
12%
19% Germany
15% USA


Acute Complications and
Eventual Remedies
Terry Klassen, MD, MSc
CoEditorinChief

The birth of a new journal
oA number of challenges
n Organizational
n Editorial
n Contentrelated
n Relational


Organizational challenges
o Twosite model: Canada & The
Netherlands
o Allocation of responsibilities
o Tight time frame for the first
year


Editorial challenges
oCreating an editorial board
oWhat is the role of an editor?


Content challenges
o Expert commentaries
n Guidelines for experts
n Role of experts in a EB journal?
o Umbrella reviews and summaries
n Evolving format
n Implement and test Cochrane developments
o Tables of key findings
n Pooling of heterogenous data
n Selecting relevant outcomes


Processes Commentary
o‘Experts’ are invited to write
commentaries based on
clinical expertise and
experience in evidence
based medicine


Processes – author/CRG
o The lead author of each review,
along with the CRG, are offered
the opportunity to review and
comment on the summary,
tables and commentary prior
to publication
o Review authors’ responses will
be published in EBCH, if desired

Processes – umbrella reviews
oUmbrella reviews are peer
reviewed prior to publication by
EB members and by external
reviewers


Relational challenges
o Review authors
n Duplicate publication?
n Can authors veto inclusion of their review?
o Cochrane Review Groups
n Extra work – for what reward?
n Conflict with module submission deadlines
o The Cochrane Collaboration
n Who owns Cochrane reviews?


Resolving these issues always
comes down to…
o The purpose of the journal –
making child health evidence
o Make Cochrane reviews
accessible and comprehensible


Central question
o What value does EBCH add to
CLIB?
n Builds on work of the Collaboration
by making child health evidence
n Translational steps involved
o We will ask our readership
n Is this the helpful format?

For more information
oChild Health Field meeting
oWednesday October 25,
12:3013:15 (tomorrow)


The Cochrane Collaboration Colloquium: Evidence Based Child Health: a Cochrane review Journal - why and how?

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The Cochrane Collaboration Colloquium: Evidence Based Child Health: a Cochrane review Journal - why and how?