Acne is the result of overactive sebaceous glands and excessive keratin production, leading to excessively oily skin that is prone to blackheads and pimples. You cannot change your skin type you cannot stop this process permanently. However, you can control this process and minimise your acne breakout reoccurrence by....

1. Managing Acne & Acne Scarring An Hands-On Approach Dr Philippa McCaffery Cosmetic Physician Sydney

6. Pathogenesis of Acne Androgens Sebocyte Keratinocyte Seborrhea Abnormal desquamation Alteration of follicular micro-environment Colonisation with P acnes Inflammation

7. Comedogenesis Microcomedo Sebocytes Follicular keratinocytes Inflammatory Lesons Closed comedo Open comedo Sebum accumulates Follicle enlarges Keratinous material builds up Sebum and fatty acids Hyperproliferation Abnormal desquamation +/- Rupture of follicle wall P acnes Immune Reactions

8. Effective treatment targets Pathophysiologic Processes Seborrhea Abnormal keratinocyte desquamation Formation of Microcomedo P acnes colonisation Pilosebaceous hyper -responsiveness excess circulating Androgens

12. Classify Acne – Mild, Moderate or Severe