In this multi-sponsor report, BioInformatics LLC will conduct an in-depth exploration of projected lab budgets and sources of funding by region, and the implications of these findings for the life science tools market in the coming year. The objective of this study is to assess sources of funding, the competitive landscape and market opportunities for life science tools companies. From the perspective of end-users, the goals of this assignment will be to: -Understand current sources of funding from government/stimulus/private foundation grants, distribution time frame and how labs initiate applications for funding. -Compare and contrast FY2013 (actual), and FY2014 (projected) average lab budgets in total by broad product category, region and market segment; providing directional information for FY2014. -Estimate scientists' budget for purchases and anticipated purchases in instrumentation and consumables, examining trends across key product categories. -Assess how optimistic scientists are regarding funding and the future of life science research. Contents, pricing and deadline ----------------------------------- BioInformatics LLC will deliver an in-depth analysis of the study's significant findings and their implications for your 2014 marketing strategy. A hard copy and an electronic version (PDF) of the final report will be provided to each sponsor. The final report will consist of the following sections: SECTION 1 - Overview and Regional Comparisons SECTION 2 - Market Analysis and Funding Situation for the United States SECTION 3 - Market Analysis for Funding Situation in Europe SECTION 4 - Market Analysis for Asia SECTION 5 - Study Methodology and Demographics SECTION 6 - Verbatim Comments from Survey Respondents Due to the high level of interest in this topic expressed by multiple life science suppliers and to defray the costs inherent in such a complex study, we are offering the report as a multi-sponsor opportunity. The fee for this study is $15,000 for each sponsor, but the report you will receive would be a $50,000-$60,000 investment for a single company to commission it individually. Please note that the deadline for inclusion in the October 2013 study is Friday, October 18, 2013.* For more information on this report, contact: Mary Follin Marketing/Sales Manager BioInformatics LLC 703.778.3080 ext. 13 m.follin@gene2drug.com www.gene2drug.com *We will require a minimum of 6 sponsors to move forward with this study, so if you could indicate your intention to participate as soon as you've made a decision, that will be helpful to us for planning purposes.

1. gene2drug.com Life Science Industry Market Research

2. Life Science Industry Market Researchgene2drug.com
Why We’re Here
• Economic landscape
• Report scope
• Being a sponsor
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Your Feedback
(Type questions in the box on the side of your screen)

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About BioInformatics LLC
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§ A full-service market research
firm since 1994:
• Published and syndicated
reports
• Consulting and strategy
development
• Expert interviews
• Focus groups
• Surveys
• RateMyProduct™

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About BioInformatics LLC
§ Conducting market
research exclusively on
scientific markets:
• Lab products
• Analytical
instrumentation
• Biotechnology research
& bioprocessing
• Drug discovery &
development
• Molecular diagnostics
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manufacturing & material science
chemical, food & beverage
environmental testing
clinical diagnostics
pharmaceutical agriculture biotech
laboratory products
life sciences

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About BioInformatics LLC
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Project team includes scientists,
statisticians and business analysts.
Instant access to a 74,000+
member expert scientific panel.
An Overview of Your Epigenetic Research
© 2009 BioInformatics, LLC www.gene2drug.com 3-17
* Totals are based on number of times an item was selected.
* Percentages are based on number of respondents.
68%
57%
55%
47%
23%
20%
14%
10%
10%
5%
0% 10% 20% 30% 40% 50% 60% 70% 80%
Gene regulation
Disease mechanisms
Biomarkers
Basic biology of epigenetics
Therapeutic targets
Stem cells
Genomic imprinting
Transgenerational epigenetic
inheritance
Tissue repair/regeneration
X chromosome inactivation
Respondents 200
Gene regulation 135
Disease mechanisms 115
Biomarkers 110
Basic biology of epigenetics 94
Therapeutic targets 46
Stem cells 41
Genomic imprinting 27
Transgenerational epigenetic
inheritance 21
X chromosome inactivation 10
Question 9*
(check all that apply)
Conduct market research for major
suppliers in the industry.

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Introduction
Robin Rothrock, Ph.D.
Director of Publications
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Overview of the
Economic Landscape

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United States
§ Sequester
§ Uncertainty regarding
healthcare reform
§ Changes in molecular
diagnostic tests coding and
reimbursement
§ Flat to declining
pharmaceutical R&D
budgets
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Europe
§ Continued fiscal austerity
§ Changes in healthcare
institutions and funding
§ Funding of research is
complex and multilayered
§ Cross-border collaboration is
increasing
§ Leading institutions are taking
action to be competitive with
the U.S. in recruiting postdocs
from India and China
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China
§ Government and
commercial investment:
>$260 billion over the next 5
years
• 500 universities
• More than 150,000 life science
graduates per year
• Four innovation clusters
• 7,500 life science companies
• 200 life science incubators
• 100 life science parks
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§ “Sea turtles” return
§ Growth in pharmaceutical
market

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A New Normal for Life Science Research
§ Slow global recovery
§ Unfavorable research funding
§ ñ pricing pressure
§ Growth in Asian markets may be slowing
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Report Scope

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Objectives
§ Understand current sources of funding
§ Compare and contrast FY2013 (actual), and FY2014
(projected) average lab budgets
§ Estimate scientists’ budget for purchases and anticipated
purchases in instrumentation and consumables
§ Take the pulse of the life science community regarding
funding and the future of life science research
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Framework
Secondary research
§ An extensive review of
relevant research councils,
funding agencies and private
funding sources
§ United States and Europe
Primary research
§ Quantitative survey
administered to life scientists
in the United States, Europe
and Asia
§ Have budget authority
§ Sample size ≅ 1,000
§ 75% academic/gov’t and
25% life science industry
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Questionnaire
§ Funding & Budgets
• Current sources of funding
• Average lab budgets (2013 and
2014)
• Average lab budgets for
instrumentation
• Average lab budgets for
consumables
• Percent budget allocation for
overhead and salaries
• Laboratory headcount
§ Techniques
• Current usage
• Explore adoption of new
products/techniques in the next
12 months
• Purchase of instrumentation
(actual in 2013 and expected in
2014)
• Identify new and emerging
technologies
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Customer Sentiment
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Will my project
be funded
next year?

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Product Categories
§ Instrumentation for…
• Cell-based analysis (flow cytometers,
high content analyzers, all
microscopes, high throughput
screening and analysis systems, etc.)
• Genome analysis (thermal cyclers,
real-time PCR instrumentation,
microarray instrumentation, NGS,
capillary electrophoresis, etc.)
• Protein analysis (chromatography,
electrophoresis, mass spectrometry,
label-free detection, calorimetry,
NMR, CD, etc.)
§ Consumables
• Cell-based analysis kits and reagents
(cell culture media and reagents,
antibodies, cell biology kits, etc.)
• Genome analysis kits and reagents
(enzymes, kits, ladders, nucleic acid
purification and separation products,
oligonucleotides [primers, RNAi], etc.)
• Protein purification and separation
kits and reagents (chromatography
media, electrophoresis matrices,
protein ladders, etc.)
• General laboratory chemicals,
plasticware, glassware and
disposables
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Cell-Based Techniques
§ Bacteria Culture
§ Cell-Based Assays
§ Confocal Microscopy
§ Eukaryotic Cell/Tissue Culture
§ Flow Cytometry
§ Fluorescence Microscopy
§ Gene Expression Analysis
§ High Content Screening
§ High-Throughput Screening
(HTS)
§ Immunohistochemistry
§ Light Microscopy
§ Stem Cell Culture/Analysis
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Genomics Techniques
§ Classical End-Point PCR
§ Cloning/Molecular biology
Techniques
§ DNA/RNA Microarrays
§ Genotyping
§ Next Generation Sequencing
§ Real-Time PCR
§ RNAi (including siRNA, miRNA)
§ Sanger DNA Sequencing
§ Single Nucleotide Polymorphism
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Protein Techniques
§ 2-D Gel Electrophoresis
§ Calorimetry (including ITC, DSC)
§ Enzyme-linked Immunosorbent
Assay (ELISA)
§ Label-Free Detection/Analysis
(Including Biosensors, SPR, etc.)
§ Light Scattering (MALS, DLS)
§ Mass Spectrometry
§ Multiplex Bead Assays
§ Protein Purification & Separation
§ Protein Structural Analysis (NMR,
CD, etc.)
§ Western Blotting
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23. Life Science Industry Market Researchgene2drug.com
Deliverable
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UK, France,
Germany,
Spain, Italy,
Switzerland &
Scandinavia
China, India,
South Korea,
Singapore &
Japan

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Why this report?

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Share Gain/Share Protect Strategies
§ Where is the growth?
§ Funding trends?
§ Are researchers pitching their
grants to follow the money?
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26. Life Science Industry Market Researchgene2drug.com
How You Can Use It
§ Check assumptions
§ Make decisions
§ Forecast revenues
§ Identify potential growth
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Benefits of Being a Sponsor
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Cost Control
Start-up Time
Expertise
Objectivity
Efficiency

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Fees
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$80,000-$100,00
Cost of sponsorship is $15,000

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Questions?

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Contact
Mary Follin
Marketing/Sales Manager
703.778.3080 x13
m.follin@gene2drug.com
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Lab Budgets and
Sources of Funding in
2014
Multi-Sponsor Research
December 2013
CALL TODAY to BECOME
A SPONSOR!