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OVERVIEW OF STI/RTI

      Dr. Ashwin C Patil
Epidemiologist And Public Health
            Expert
Sexually Transmitted Infections (STI) / Sexually
          Transmitted Diseases (STD)

Infections caused by germs such as
 bacteria, viruses, ,protozoa or fungi that are passed
 from one person to another through sexual contact.
Non- sexual modes of transmission?????
                   YES…..
Reproductive Tract Infections (RTI)
• Any infection of the reproductive tract.
• Include both STI and non-sexually transmitted
  infections.
• May not be sexually transmitted and can be
  caused by disturbance of the normal
  endogenous flora and by medical interventions
  that may provoke iatrogenic infection.
Routes Of Transmission Of STI/RTI

• Unsafe sex
• Procedures like unsafe abortions, unsafe delivery, etc.
• Unsafe blood transfusions.


RTI in both men and women include STI and are mainly due to
                  unsafe sexual practices

                 RTI in women also include
 Break in normal vaginal flora (candida and bacterial vaginosis)
            Postpartum and post abortion infections
                     Following procedures
Factors that increase the risk of RTI
• Poor general health
• Poor genital hygiene
• Poor menstrual hygiene
• Unhygienic practices by service providers during
  delivery, abortion , MTP and IUCD
• RTI –undiagnosed and untreated - infertility
  , ectopic pregnancy & cervical cancer.
Factors that increase the risk of STI


• Unprotected sex
• Multiple Partners
• Sex with Partner having sore on the genital
  region, urethral discharge or infected vaginal discharge
• Previous STI infection in the past year
Risk groups
•   Adolescent girls and boys
•   Women who have several partners
•   Female and male sex workers and their clients
•   Men and women are away from home for long duration
•   MSM including trans-genders.
•   Street children, prison inmates, etc.
Where STI/RTI occur in females ?
                • Vagina and cervix :
                  Lower reproductive
                  tract infections.
                • Uterus, fallopian
                  tubes, and ovaries-
                  Upper reproductive
                  tract infections.
Where STI/RTI occur in males?

• Urethra : Lower reproductive tract.
• Epididymis and testes : Upper reproductive tract.
The most common RTI but not always sexually
transmitted:

  • Bacterial Vaginosis (BV) - A RTI in women that is
    caused by an imbalance in the vagina’s normal
    environment and overgrowth of bacteria in the
    vagina.
  • Vaginal yeast infection- A RTI in women that occurs
    when the normal environment in the vagina changes
    and there is overgrowth of yeast, commonly candida
    albicans.
Over 20 STI, But the most common
STI              Organism                 Signs and symptoms

Syphilis (M&     Treponema Pallidum       Sores - Heal on their own.Untreated -
F)                                        Serious complications or death

Gonorrhea        Neisseria gonorrhoea     Infertility, ophthalmia neonatarum.
(M& F)
Chlamydia        Chlamydia trachomatis    Often asymptomatic.
(M& F)
Trichomoniasis Trichomonas vaginalis      often asymptomatic
(M& F)
Chancroid        Haemophilus ducreyi      lymph node swelling and painful ulcers
                                          .
Genital herpes   Herpes simplex virus     Painful genital ulcers

Genital and      Human papilloma virus    Cervical cancer.
cervical warts   (HPV)
HIV infection    Human immunodeficiency   Weakens the immune system and
                 virus                    causes AIDS.
STI               Organism                       Signs and symptoms

Hepatitis B &     HBV,HCV                        Liver damage, liver failure
Hepatitis C

Donovanosis       Calymmatobacterium              Ulcers at the site of infection. Ulcers
                  granulomatis or Kleibsella     can grow together - permanent scarring
                  Granulomatis                   and genital destruction.
Lymphogranulo Chlamydia trachomatis               Prevents drainage of the lymph nodes
ma venereum                                      in the genital area. Destruction and
(LGV)                                            scarring of surrounding tissue
Molluscum                                        Benign skin and secondary bacterial
contagiosum                                      infections
Genital scabies   Itch mite, sarcoptis scabiei
(M &F)
Pubic lice        Pubic lice (Phthirus
(M &F)            pubis).
Signs and Symptoms of STI/RTI
Men :
• Urethral discharge and Genital itching :
  chlamydia, gonorrhea and trichomonas infection
• Genital ulcer: T. Pallidum, H. Ducreyi.
• Swollen and/or painful testicles: chlamydia, gonorrhea
Women

• Unusual vaginal discharge:
  BV, Chlamydia, gonorrhoea, trichomonas
  infection, vaginal yeast infection
• Genital itching: BV, trichomonas infection, vaginal yeast
  infection
• Abnormal and/or heavy vaginal bleeding:
  chlamydia, gonorrhea
• Bleeding after intercourse:
  chlamydia, gonorrhoea, chancroid and genital herpes
• Lower abdominal pain : chlamydia, gonorrhoea
• Persistent vaginal candidiasis: HIV/AIDS
• Dyspareunia
Complications of STI/RTI in males


•   Phimosis, paraphimosis and urethral stricture
•   Inflammation of testes
•   Infertility
•   Carcinoma of the penis
Complications of STI/RTI in females
•   Pelvic inflammatory disease
•   Adverse outcomes of pregnancy:
•   Fetal wastage - spontaneous abortion or stillbirth.
•   Low birth weight due to premature delivery or
    intra-uterine growth retardation.
•   Congenital or perinatal infections - eye infections
    causing blindness, infant pneumonias and mental
    retardation.
•   Infertility
•   Ectopic pregnancy
•   Cervical cancer
Human Papilloma Virus
       (HPV)
• Non- sexual mode
  of transmission.
• Skin to skin contact.
• Cervical warts –
  Ca??
• Pink or flesh-colored
  warts- raised, flat, or
  cauliflower shaped.
• Often- no
  symptoms.
Crabs (Pubic Lice)

          • Crabs: Lice
          • The creatures crawl from
            one person to another
            during close contact.
          • Symptoms: Intense
            itching, tiny eggs
            attached to pubic hair, or
            crawling lice.
Scabies

   • It is not always an STD,
     as it can spread through
     any skin-to-skin contact.
   • But among young adults,
     the mites are often
     acquired during sex.
   • Symptoms: Intense
     itching especially at
     night and a pimple-like
     rash.
Gonorrhea
• Symptoms:
• Burning during urination
  and discharge, skin rashes
  or spread to the joints and
  blood.

• In Men: Discharge from
  the penis, swollen testicles
  , red and tender urethra

• In Women: purulant /
  muco-purulant Vaginal
  discharge, pelvic pain,
  spotting.
Syphilis
  • Without treatment, it can
    lead to
    paralysis, blindness, and
    death.
  • Signs and Symptoms:
  • firm, round, painless sore
    on the genitals or anus.
    Spreads through direct
    contact with this sore.
  • Rash on the
    soles, palms, or other parts
    of the body swollen
    glands, fever, hair loss, or
    fatigue.
  • Heart
Chlamydia

• May infect the rectum and
  throat.
• Symptoms in Men:
  Burning and itching at the
  tip of the
  penis, discharge, painful
  urination.
• Symptoms in Women:
  Vaginal itching, discharge
  that may have an
  odor, pain during
  sex, painful urination. Red
  cervix which bleeds.
Herpes Simplex Virus Type 1
           • Usually not an STD;
           • Spreads easily among household
             members or through kissing.
           • Spread to the genitals through oral
             or genital contact with an infected
             person.
           • No cure, drugs can shorten or
             prevent outbreaks.

           • Signs and Symptoms: Occasional
             cold sores or “fever blisters” on
             the lips. Small blister or sores on
             the genitals.
Herpes Simplex Virus
              Type 2
•   Highly contagious
•   Spread through
    intercourse or direct
    contact with a herpes
    sore.
•   No cure.
•   Symptoms: Fluid-filled
    blisters that form
    painful, crusted sores
    on the
    genitals, anus, thighs, or
    buttocks. Can spread to
    the lips through oral
    contact.
Hepatitis B
• Severe liver damage.
• Spreads through contact with
  blood and other body
  fluids, sex, needle
  sharing, and at birth, sharing
  razors and toothbrushes.
• No cure, effective vaccine
• Symptoms:
• Nausea, belly pain, dark
  urine, fatigue, and a
  yellowing of the skin or eyes
  with acute infection. liver
  cirrhosis and liver cancer.
HIV
  Spreads through
  unprotected sex, needle
  sharing, or being born to
  an infected mother.
  Early symptoms of HIV
  Infection:
  flu-like symptoms 1-2
  months after infection:
  swollen glands
  a fever, headaches, and
  fatigue.
  Canker sores in the mouth
Trichomoniasis
       • Spreads during sexual
         contact. It can be cured
         with prescription drugs.
       • Signs and Symptoms in
         Men: mild discharge or
         slight burning during
         urination.
       • Signs and Symptoms in
         Women: Frothy yellow-
         green discharge with a
         strong odor, vaginal
         itching, or pain during
         sex or urination.
Chancroid
    • Bacterial STD common in Africa
      and Asia but rare in the U.S.
    • genital sores that can spread the
      bacteria from one person to
      another.
    • Symptoms in Men: Painful
      bumps on the penis that may
      develop into pus-filled open
      sores, pain in the genitals and
      groin.
    • Symptoms in Women: Painful,
      bumps in the genital area that can
      develop into open sores, swollen
      lymph nodes in the groin.
LGV (Lymphogranuloma Venereum)

                • More common in MSM.
                  Can be cured with
                • Symptoms: Open sores
                  on the genitals or
                  anus, headache, fever, fati
                  gue, and swollen lymph
                  glands in the groin. If
                  acquired through anal
                  sex, LGV may cause
                  rectal bleeding or
                  discharge.
Pelvic Inflammatory Disease
               • Not an STD itself, PID is a
                 serious complication of
                 untreated STDs, especially
                 chlamydia and gonorrhea.
               • Signs and Symptoms:
                 Lower abdominal
                 pain, fever, unusual
                 discharge, painful
                 intercourse, painful
                 urination, and spotting.
Overview of STI
Overview of STI
Overview of STI
Overview of STI

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Overview of STI

  • 1. OVERVIEW OF STI/RTI Dr. Ashwin C Patil Epidemiologist And Public Health Expert
  • 2. Sexually Transmitted Infections (STI) / Sexually Transmitted Diseases (STD) Infections caused by germs such as bacteria, viruses, ,protozoa or fungi that are passed from one person to another through sexual contact. Non- sexual modes of transmission????? YES…..
  • 3. Reproductive Tract Infections (RTI) • Any infection of the reproductive tract. • Include both STI and non-sexually transmitted infections. • May not be sexually transmitted and can be caused by disturbance of the normal endogenous flora and by medical interventions that may provoke iatrogenic infection.
  • 4. Routes Of Transmission Of STI/RTI • Unsafe sex • Procedures like unsafe abortions, unsafe delivery, etc. • Unsafe blood transfusions. RTI in both men and women include STI and are mainly due to unsafe sexual practices RTI in women also include Break in normal vaginal flora (candida and bacterial vaginosis) Postpartum and post abortion infections Following procedures
  • 5.
  • 6. Factors that increase the risk of RTI • Poor general health • Poor genital hygiene • Poor menstrual hygiene • Unhygienic practices by service providers during delivery, abortion , MTP and IUCD • RTI –undiagnosed and untreated - infertility , ectopic pregnancy & cervical cancer.
  • 7. Factors that increase the risk of STI • Unprotected sex • Multiple Partners • Sex with Partner having sore on the genital region, urethral discharge or infected vaginal discharge • Previous STI infection in the past year
  • 8. Risk groups • Adolescent girls and boys • Women who have several partners • Female and male sex workers and their clients • Men and women are away from home for long duration • MSM including trans-genders. • Street children, prison inmates, etc.
  • 9. Where STI/RTI occur in females ? • Vagina and cervix : Lower reproductive tract infections. • Uterus, fallopian tubes, and ovaries- Upper reproductive tract infections.
  • 10. Where STI/RTI occur in males? • Urethra : Lower reproductive tract. • Epididymis and testes : Upper reproductive tract.
  • 11. The most common RTI but not always sexually transmitted: • Bacterial Vaginosis (BV) - A RTI in women that is caused by an imbalance in the vagina’s normal environment and overgrowth of bacteria in the vagina. • Vaginal yeast infection- A RTI in women that occurs when the normal environment in the vagina changes and there is overgrowth of yeast, commonly candida albicans.
  • 12. Over 20 STI, But the most common STI Organism Signs and symptoms Syphilis (M& Treponema Pallidum Sores - Heal on their own.Untreated - F) Serious complications or death Gonorrhea Neisseria gonorrhoea Infertility, ophthalmia neonatarum. (M& F) Chlamydia Chlamydia trachomatis Often asymptomatic. (M& F) Trichomoniasis Trichomonas vaginalis often asymptomatic (M& F) Chancroid Haemophilus ducreyi lymph node swelling and painful ulcers . Genital herpes Herpes simplex virus Painful genital ulcers Genital and Human papilloma virus Cervical cancer. cervical warts (HPV) HIV infection Human immunodeficiency Weakens the immune system and virus causes AIDS.
  • 13. STI Organism Signs and symptoms Hepatitis B & HBV,HCV Liver damage, liver failure Hepatitis C Donovanosis Calymmatobacterium Ulcers at the site of infection. Ulcers granulomatis or Kleibsella can grow together - permanent scarring Granulomatis and genital destruction. Lymphogranulo Chlamydia trachomatis Prevents drainage of the lymph nodes ma venereum in the genital area. Destruction and (LGV) scarring of surrounding tissue Molluscum Benign skin and secondary bacterial contagiosum infections Genital scabies Itch mite, sarcoptis scabiei (M &F) Pubic lice Pubic lice (Phthirus (M &F) pubis).
  • 14. Signs and Symptoms of STI/RTI Men : • Urethral discharge and Genital itching : chlamydia, gonorrhea and trichomonas infection • Genital ulcer: T. Pallidum, H. Ducreyi. • Swollen and/or painful testicles: chlamydia, gonorrhea
  • 15. Women • Unusual vaginal discharge: BV, Chlamydia, gonorrhoea, trichomonas infection, vaginal yeast infection • Genital itching: BV, trichomonas infection, vaginal yeast infection • Abnormal and/or heavy vaginal bleeding: chlamydia, gonorrhea • Bleeding after intercourse: chlamydia, gonorrhoea, chancroid and genital herpes • Lower abdominal pain : chlamydia, gonorrhoea • Persistent vaginal candidiasis: HIV/AIDS • Dyspareunia
  • 16. Complications of STI/RTI in males • Phimosis, paraphimosis and urethral stricture • Inflammation of testes • Infertility • Carcinoma of the penis
  • 17. Complications of STI/RTI in females • Pelvic inflammatory disease • Adverse outcomes of pregnancy: • Fetal wastage - spontaneous abortion or stillbirth. • Low birth weight due to premature delivery or intra-uterine growth retardation. • Congenital or perinatal infections - eye infections causing blindness, infant pneumonias and mental retardation. • Infertility • Ectopic pregnancy • Cervical cancer
  • 18.
  • 19. Human Papilloma Virus (HPV) • Non- sexual mode of transmission. • Skin to skin contact. • Cervical warts – Ca?? • Pink or flesh-colored warts- raised, flat, or cauliflower shaped. • Often- no symptoms.
  • 20. Crabs (Pubic Lice) • Crabs: Lice • The creatures crawl from one person to another during close contact. • Symptoms: Intense itching, tiny eggs attached to pubic hair, or crawling lice.
  • 21. Scabies • It is not always an STD, as it can spread through any skin-to-skin contact. • But among young adults, the mites are often acquired during sex. • Symptoms: Intense itching especially at night and a pimple-like rash.
  • 22. Gonorrhea • Symptoms: • Burning during urination and discharge, skin rashes or spread to the joints and blood. • In Men: Discharge from the penis, swollen testicles , red and tender urethra • In Women: purulant / muco-purulant Vaginal discharge, pelvic pain, spotting.
  • 23. Syphilis • Without treatment, it can lead to paralysis, blindness, and death. • Signs and Symptoms: • firm, round, painless sore on the genitals or anus. Spreads through direct contact with this sore. • Rash on the soles, palms, or other parts of the body swollen glands, fever, hair loss, or fatigue. • Heart
  • 24. Chlamydia • May infect the rectum and throat. • Symptoms in Men: Burning and itching at the tip of the penis, discharge, painful urination. • Symptoms in Women: Vaginal itching, discharge that may have an odor, pain during sex, painful urination. Red cervix which bleeds.
  • 25. Herpes Simplex Virus Type 1 • Usually not an STD; • Spreads easily among household members or through kissing. • Spread to the genitals through oral or genital contact with an infected person. • No cure, drugs can shorten or prevent outbreaks. • Signs and Symptoms: Occasional cold sores or “fever blisters” on the lips. Small blister or sores on the genitals.
  • 26. Herpes Simplex Virus Type 2 • Highly contagious • Spread through intercourse or direct contact with a herpes sore. • No cure. • Symptoms: Fluid-filled blisters that form painful, crusted sores on the genitals, anus, thighs, or buttocks. Can spread to the lips through oral contact.
  • 27. Hepatitis B • Severe liver damage. • Spreads through contact with blood and other body fluids, sex, needle sharing, and at birth, sharing razors and toothbrushes. • No cure, effective vaccine • Symptoms: • Nausea, belly pain, dark urine, fatigue, and a yellowing of the skin or eyes with acute infection. liver cirrhosis and liver cancer.
  • 28. HIV Spreads through unprotected sex, needle sharing, or being born to an infected mother. Early symptoms of HIV Infection: flu-like symptoms 1-2 months after infection: swollen glands a fever, headaches, and fatigue. Canker sores in the mouth
  • 29. Trichomoniasis • Spreads during sexual contact. It can be cured with prescription drugs. • Signs and Symptoms in Men: mild discharge or slight burning during urination. • Signs and Symptoms in Women: Frothy yellow- green discharge with a strong odor, vaginal itching, or pain during sex or urination.
  • 30. Chancroid • Bacterial STD common in Africa and Asia but rare in the U.S. • genital sores that can spread the bacteria from one person to another. • Symptoms in Men: Painful bumps on the penis that may develop into pus-filled open sores, pain in the genitals and groin. • Symptoms in Women: Painful, bumps in the genital area that can develop into open sores, swollen lymph nodes in the groin.
  • 31. LGV (Lymphogranuloma Venereum) • More common in MSM. Can be cured with • Symptoms: Open sores on the genitals or anus, headache, fever, fati gue, and swollen lymph glands in the groin. If acquired through anal sex, LGV may cause rectal bleeding or discharge.
  • 32. Pelvic Inflammatory Disease • Not an STD itself, PID is a serious complication of untreated STDs, especially chlamydia and gonorrhea. • Signs and Symptoms: Lower abdominal pain, fever, unusual discharge, painful intercourse, painful urination, and spotting.