1. Medidata & Amazon
Web Services
Glenn Watt | Corporate Information Security & Privacy
Officer
June 10 2011
Optimizing Clinical Trials:
Concept to Conclusion™
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  1

2. Company Snapshot
Leading provider of SaaS technology solutions that drive efficiencies
across the clinical research process, lowering cost of clinical development
• Founded: 1999
• Headquarters: New York City
• Locations: 9 offices across U.S., U.K.,
Japan and China
• Headcount: 710+
• Customers: 215+ customers include
22 of Top 25 bio-pharma
companies
• Addressable Bio-pharma clinical
Market Size: development trial spend =
$53B*
• Public Co: NASDAQ: MDSO
$615M+ market cap (3/11)
• Balance Sheet: $89M cash and marketable
securities
* Phases I-IV, not including pre-clinical expense, labs, or other
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  2

3. Global Business
Study design data for over
27,500 protocols
Live data infrastructure for over
2,000 studies, with over
2,000,000 subjects
Financial transactions from over
260,000 site grants and 8,000
CRO contracts
Medidata Technology Used in Over 100 Countries
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  3

4. Medidata’s Product Platform
1999 2011
EDC
Early CDMS
Lab Administration
Hybrid Studies
Full Multilingual CDMS
Open API & Developer Central
Enhanced Reporting and Data Handling
Monitor
Safety Gateway
Targeted SDV
AM 2.0
Tech Stack
Designer Gateway
Designer 3.0
GM 3.0
Contracting
Medidata spends 16% of revenue on Research & Development
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  4

5. Broad Customer Base
Institutions Biopharmaceutical
Medical Devices CROs/Service Providers
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  5

6. How Medidata Uses AWS Today
Medidata leverages Elastic Compute Cloud, Simple Storage Solution,
Relational Database service, Elastic Block Store and Elastic Load Balancing
• iMedidata
• Simplified eLearning and user administration
• Launched on AWS in July, 2010
• Balance
• Powerful dynamic allocation and supply planning
• Launched on AWS in July, 2010
• Grants Manager
• Rapid trial forecast and budget development
• Transitioned to AWS in June, 2010
• Coder
• Streamlined enterprise-grade coding
• To be launched on AWS in July, 2011
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  6

7. Selecting the Right Cloud Vendor
After more than a year of diligence, AWS was the choice for data security
AWS Vendor X Vendor Y Vendor Z
Strong Regulatory
Compliance    
SAS 70 Type II    
   
FISMA
ISO 27000 based
Security Policies    
Redundant Zones for
Business Continuity    
Privacy Compliance
(Safe Harbor)    
 
  
Information Security
Interoperability
   
Source: Medidata Solutions
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  7

8. Medidata Architecture and Deployment
• Opinionated Deployments
• Architectures deployed in
common, best practice way
• Simplifies upgrades
• Ensures strict adherence to SLA,
security, backup, and DR policies
• Common Architectures
• Limited, approved set of
technologies
• OS, database, monitoring, load
balancing, firewalls
• Fully Scripted Deployments
• Using configuration
management software
• Timely, easy releases and upgrades
• Better emergency response
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  8

9. How Medidata Plans to Use AWS
• Increase Medidata transactions on AWS
• Transition existing products to AWS
• Transition existing customers to AWS
• Introduce new products on AWS
• Leverage more AWS solutions across Medidata portfolio
• SimpleDB
• Simple Queue Service
• Simple Notification Service
• Elastic Map Reduce
Optimizing Clinical Trials: Concept to Conclusion TM © 2011 Medidata Solutions, Inc. – Proprietary and Confidential  9