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Stem Cells

Revolution in Horse Therapies
Protectas Health
Dermot Dougan           Terry Sullivan       Matti Viio
    Director                Chairman
                                                Director




                       David Crimmins
                        Managing Director




 Margaret Goggin                            Andrew Neal
  Head of Laboratory                         Chief Technical
                                                Officer
Mission
• Extract stem cells from umbilical cord blood



• Store stem cells in cryogenic freezers



• Insurance for the health of horses - “Repair Kit”



• Stud Farm own the cells
Equine Stem Cells
• Primal cells that can develop into any cell



• Provide repair kit for life time of horse



• Extracted from 3 sources, Bone Marrow, Fat & Umbilical Cord



• Significant advantages over other sources of stem cells
Cord Blood Stem Cells
• Non invasive with little interference in foaling process


• No surgical procedure required


• In rawest and least mature state, better quality, plentiful supply


• Better condition as age damage is minimised
Horse Treatments
    Tendon Injuries - 82% success v 44% traditional1 Suspensory

    Ligaments – 92% success v 15% traditional2

    Osteoarthritis, OCD’s, Sesamoid Injuries, Fractures


    In the pipeline:

             Laminitis, Heaves, Bleeders, Reproductive Problems

1 The Horse Report,Vol 26 No. 4, 2008 Centre for Equine Health, School of Veterinary Medicine, University of California, Davis
2 Herthel Proceedings of Annual Convention of American Association Equine Practioners 2001
Procedure
• No change to natural foaling process

• Use supplied equipment to collect cord blood

• No Vet needed

• Training provided by Protectas Health
Intellectual Property
• Process based on a ‘closed system’

                                                    TM
• Patents lodged for unique storage bag, proteCELL

• Further Patents on process, syringe and spinning bag

• Irish Medicines Board have deemed product medicine

• IP will cover all veterinary and human applications
Competitive Advantages
• 1st in world to take foal cord blood & extract stem cells

• Competitive cost base, fully regulated & scaleable process

• Clients incl. worlds largest stud farms, repeat business

• Based in Ireland, unique tax advantages and equine status

• Option on insurance deal w/No.1 insurer in UK & USA
Potential
• 118,000 thoroughbred foals born p.a.


• USA, Australia, Ireland dominate breeding


• Thoroughbreds only start
  • 3.5m Quarter Horses in USA

  • Sports Horses

  • Polo Horses

  • Eventing

  • Endurance Horses.......................
Thank You

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Harvesting Equine Umbilical Cord Stem Cells

  • 1. Stem Cells Revolution in Horse Therapies
  • 2. Protectas Health Dermot Dougan Terry Sullivan Matti Viio Director Chairman Director David Crimmins Managing Director Margaret Goggin Andrew Neal Head of Laboratory Chief Technical Officer
  • 3. Mission • Extract stem cells from umbilical cord blood • Store stem cells in cryogenic freezers • Insurance for the health of horses - “Repair Kit” • Stud Farm own the cells
  • 4. Equine Stem Cells • Primal cells that can develop into any cell • Provide repair kit for life time of horse • Extracted from 3 sources, Bone Marrow, Fat & Umbilical Cord • Significant advantages over other sources of stem cells
  • 5. Cord Blood Stem Cells • Non invasive with little interference in foaling process • No surgical procedure required • In rawest and least mature state, better quality, plentiful supply • Better condition as age damage is minimised
  • 6. Horse Treatments Tendon Injuries - 82% success v 44% traditional1 Suspensory Ligaments – 92% success v 15% traditional2 Osteoarthritis, OCD’s, Sesamoid Injuries, Fractures In the pipeline: Laminitis, Heaves, Bleeders, Reproductive Problems 1 The Horse Report,Vol 26 No. 4, 2008 Centre for Equine Health, School of Veterinary Medicine, University of California, Davis 2 Herthel Proceedings of Annual Convention of American Association Equine Practioners 2001
  • 7. Procedure • No change to natural foaling process • Use supplied equipment to collect cord blood • No Vet needed • Training provided by Protectas Health
  • 8. Intellectual Property • Process based on a ‘closed system’ TM • Patents lodged for unique storage bag, proteCELL • Further Patents on process, syringe and spinning bag • Irish Medicines Board have deemed product medicine • IP will cover all veterinary and human applications
  • 9. Competitive Advantages • 1st in world to take foal cord blood & extract stem cells • Competitive cost base, fully regulated & scaleable process • Clients incl. worlds largest stud farms, repeat business • Based in Ireland, unique tax advantages and equine status • Option on insurance deal w/No.1 insurer in UK & USA
  • 10. Potential • 118,000 thoroughbred foals born p.a. • USA, Australia, Ireland dominate breeding • Thoroughbreds only start • 3.5m Quarter Horses in USA • Sports Horses • Polo Horses • Eventing • Endurance Horses.......................