1. 10-12
10-9
10-6
10-3
100
103
106
Sec
N
NH2
ON
O
OHO
HH
HH
PO
O-
HO
O-
Bond
liberation
Base
Wobbling Catalysis
Ligand Binding Translation
Transcription
Life of mRNA in vivo
RNA folding
Helical motions
Virus
replication
Spin Relaxation
Residual Dipolar Coupling Time resolved NMR
R1ρ H exchange H-D exchange
CPMG
2-6 kcal/mol
9-12 kcal/mol
13-16 kcal/mol
>17 kcal/mol
Free
Energy
NMR
Experiments
RNA
Dynamics