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Concept 19.4: Eukaryotic Genomes can
have many noncoding DNA sequences in
           addition to genes

    WILL S., MICHELLE K., REX L., MAYA H.
Remember Transposable Elements?

 Chapter 18: nucleic acid
  segments,
                                PROKARYOTES
  recombination
  (movement) within
  genome
 Chapter 19:
  EUKARYOTES
 1940s – 1950s Barbara
  McClintock
    Bred corn
    Different kernel colors
What are Transposons and Retrotransposons?

 Eukaryote Transposons 2 types:


    Transposons: transposable elements
     move using DNA intermediate




    Retrotransposons: transposable
     elements move using RNA intermediate
     (transcript of the retrotransposon DNA)
How do these Transposons Move?

 Cut & Paste
 Copy & Paste
 RNA = ALWAYS
 Copy & Paste
    RNA intermediate
     made
    Reverse
     transcriptase 
     transposon copy
    Insertion new place
 Evolutionary
 Advantage
Sequences Related to Transposable Elements

 Many copies
 Some similar some not
 Some move some can’t
    Move through enzymes
 Make up large part of
  genome
 Alu elements – 10%
  human genome
    Codes for RNA molecules
 Most transposable
 elements = “noncoding”
 DNA
Is there an animation to simplify all of these
                  words?



               Yes!
               (that may have been overenthusiastic)

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Eukaryotic Genomes Contain Noncoding DNA Like Transposable Elements

  • 1. Concept 19.4: Eukaryotic Genomes can have many noncoding DNA sequences in addition to genes WILL S., MICHELLE K., REX L., MAYA H.
  • 2. Remember Transposable Elements?  Chapter 18: nucleic acid segments,  PROKARYOTES recombination (movement) within genome  Chapter 19: EUKARYOTES  1940s – 1950s Barbara McClintock  Bred corn  Different kernel colors
  • 3. What are Transposons and Retrotransposons?  Eukaryote Transposons 2 types:  Transposons: transposable elements move using DNA intermediate  Retrotransposons: transposable elements move using RNA intermediate (transcript of the retrotransposon DNA)
  • 4. How do these Transposons Move?  Cut & Paste  Copy & Paste  RNA = ALWAYS Copy & Paste  RNA intermediate made  Reverse transcriptase  transposon copy  Insertion new place  Evolutionary Advantage
  • 5. Sequences Related to Transposable Elements  Many copies  Some similar some not  Some move some can’t  Move through enzymes  Make up large part of genome  Alu elements – 10% human genome  Codes for RNA molecules  Most transposable elements = “noncoding” DNA
  • 6. Is there an animation to simplify all of these words? Yes! (that may have been overenthusiastic)