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Telemonitoring for Heart Failure Evidence & Practice Professor John G.F. Cleland Department of Cardiology, Hull Y o rk Medical School University of Hull Kingston-upon-Hull UK Conflict of Interest:  I have received honoraria and/or research support from Philips, Bosch, GE, Alere and St Jude
[object Object],Survival of Patients with a Primary Discharge Diagnosis of Heart Failure England & Wales 2009-2010 About 1 million people affected in the UK ~450,000 admissions per year (65,000 in first diagnostic position) N = 19,240  (about 30% of all expected cases) Median age 79 years <65 years  ~3,000  65-75 years  ~4,000 75-85 years  ~7,000 >85 years  ~5,000  Cleland et al HEART 2011
TeleHealth Why is it Likely to Become Essential? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TeleHealth Why is it Likely to Become Essential? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Opportunity of Chronic Illness ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TeleHealth - What Might it Achieve? Ultimate Intermediate
TEN-HMS The Trans-European Network–Home-Care Management System Patients about to be discharged from hospital after an exacerbation of chronic heart failure (Published JACC 2005) 54% of Patients Aged >70 years
p < 0,05 Mortality Cleland et al JACC 2005 TEN-HMS Reduction in Mortality NTS or HTM v UC Absolute 16.4% Relative  36 % No reduction in hospitalisation Shortening of hospital stay with HTM
TEN-HMS much safer safer no change more anxious much more anxious “  How do you feel about your health since receiving Telemonitoring? “ Undef.
TEN-HMS 120 Days 240 Days % *** *** *** ***  differences between HTM and other groups. No difference between UC and NTS Achieving Therapeutic Target 240 Days Patient Clinical Status
TEN-HMS: Total Patient Contacts Contacts Per 1,000 Days Alive and Out of Hospital # # under-reporting of events likely in this group P<0.01 HTM v NTS
Structured Telephone Support n = 5,563 (Cochrane Review) Mortality Inglis et al 2010  HR 0.88 (0.76-1.01); p=0.08 ,[object Object],[object Object],[object Object],All-Cause Hospitalisation HR 0.77 (0.68-0.87.01); p<0.0001
Home Telemonitoring n = 2,710   (Cochrane Review) Inglis et al 2010   Mortality HR 0.66 (0.54-0.87); p<0.0001 ,[object Object],[object Object],[object Object],[object Object],[object Object],All-Cause Hospitalisation HR 0.91 (0.84-0.99); p=0.02
Major Problems with RCTs  of Service Delivery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Percent of Days Lost To Hospitalisation or Death 8.9%  8.4% 37.0% 21.3%  22.6% TEN-HMS (15 months) TIM-HF (26 months) TEHAF (12 months) 4.5%  6.1%
What Have We Done for TeleHealth in Hull? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Hull Model for TeleHealth Non-Invasive Home Monitoring Community TeleKiosks Screening Long-Term Conditions Device Implant ,[object Object],[object Object],[object Object],MEMS-based pressure sensor
Services for Patients with Heart Failure The Kingston-upon-Hull Model Heart Failure  Discharge Nurse Heart Failure Telemonitoring Nurse Community Heart Failure Specialist Nurses Patients in Hospital Patients at Home Voluntary  Patient-Support Organisations Specialist Clinics Family Doctor (NT-proBNP)
Cost-Effectiveness of  TeleHealth (Hull)
Where Next? ,[object Object],[object Object],[object Object],[object Object],[object Object],Centre for Telehealth
The Hull Heart Failure Life-Lab 30,000 patient-years of follow-up Largest, Longest Follow-up, Epidemiologically-Representative Cohort of Heart Failure in the World Rich in phenotyping, serial biomarker and outcome data
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],HeartCycle Programme
Patient / Carer Communication  System ‘ Monitor’ Analysis Health-Care Provider Secondary  Loop Primary  Loop 70% of Care Decisions Motivation: feedback on measures and trends, what they mean and what to do about them Education: on healthy lifestyle, reasons for treatments, self management Intelligent, integrated, multi-measure (time & type) personalised analysis
Opportunities for TeleHealth ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object]
 

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Wsdanjohncleland

  • 1. Telemonitoring for Heart Failure Evidence & Practice Professor John G.F. Cleland Department of Cardiology, Hull Y o rk Medical School University of Hull Kingston-upon-Hull UK Conflict of Interest: I have received honoraria and/or research support from Philips, Bosch, GE, Alere and St Jude
  • 2.
  • 3.
  • 4.
  • 5.
  • 6. TeleHealth - What Might it Achieve? Ultimate Intermediate
  • 7. TEN-HMS The Trans-European Network–Home-Care Management System Patients about to be discharged from hospital after an exacerbation of chronic heart failure (Published JACC 2005) 54% of Patients Aged >70 years
  • 8. p < 0,05 Mortality Cleland et al JACC 2005 TEN-HMS Reduction in Mortality NTS or HTM v UC Absolute 16.4% Relative 36 % No reduction in hospitalisation Shortening of hospital stay with HTM
  • 9. TEN-HMS much safer safer no change more anxious much more anxious “ How do you feel about your health since receiving Telemonitoring? “ Undef.
  • 10. TEN-HMS 120 Days 240 Days % *** *** *** *** differences between HTM and other groups. No difference between UC and NTS Achieving Therapeutic Target 240 Days Patient Clinical Status
  • 11. TEN-HMS: Total Patient Contacts Contacts Per 1,000 Days Alive and Out of Hospital # # under-reporting of events likely in this group P<0.01 HTM v NTS
  • 12.
  • 13.
  • 14.
  • 15. Percent of Days Lost To Hospitalisation or Death 8.9% 8.4% 37.0% 21.3% 22.6% TEN-HMS (15 months) TIM-HF (26 months) TEHAF (12 months) 4.5% 6.1%
  • 16.
  • 17.
  • 18. Services for Patients with Heart Failure The Kingston-upon-Hull Model Heart Failure Discharge Nurse Heart Failure Telemonitoring Nurse Community Heart Failure Specialist Nurses Patients in Hospital Patients at Home Voluntary Patient-Support Organisations Specialist Clinics Family Doctor (NT-proBNP)
  • 19. Cost-Effectiveness of TeleHealth (Hull)
  • 20.
  • 21. The Hull Heart Failure Life-Lab 30,000 patient-years of follow-up Largest, Longest Follow-up, Epidemiologically-Representative Cohort of Heart Failure in the World Rich in phenotyping, serial biomarker and outcome data
  • 22.
  • 23. Patient / Carer Communication System ‘ Monitor’ Analysis Health-Care Provider Secondary Loop Primary Loop 70% of Care Decisions Motivation: feedback on measures and trends, what they mean and what to do about them Education: on healthy lifestyle, reasons for treatments, self management Intelligent, integrated, multi-measure (time & type) personalised analysis
  • 24.
  • 25.
  • 26.